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Quality of Life Research
Published in: Quality of Life Research 8/2016

Open Access 01-08-2016

The validity and responsiveness of the ICECAP-A capability-well-being measure in women with irritative lower urinary tract symptoms

Authors: Ilias Goranitis, Joanna Coast, Hareth Al-Janabi, Pallavi Latthe, Tracy E. Roberts

Published in: Quality of Life Research | Issue 8/2016

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Abstract

Purpose

A desire to incorporate broader aspects of well-being in health economic evaluations has led to the development of the ICEpop CAPability measure for Adults (ICECAP-A). The ICECAP-A draws upon Amartya Sen’s capability approach and conceptualises well-being as the capability to achieve Stability, Attachment, Autonomy, Achievement, and Enjoyment. The aim of this study was to assess the psychometric performance of the ICECAP-A in a context where patient outcomes can extend beyond health-related quality of life.

Methods

Longitudinal data were collected for 478 women with symptoms of urinary frequency and urgency, with or without incontinence. Women were recruited across 22 hospitals in the UK and had a mean age of 55 (SD 14). The psychometric performance of the measure was evaluated in relation to the EuroQol Five-Dimension Questionnaire (EQ-5D-3L) and the International Consultation on Incontinence Questionnaire for Overactive Bladder (ICIQ-OAB) and involved an assessment of acceptability, construct validity, and responsiveness using parametric and nonparametric methods.

Results

ICECAP-A showed good convergence with the ICIQ-OAB with 20 out of 22 expected patterns of relationship confirmed. Findings suggested that the ICECAP-A has better discriminative properties than EQ-5D-3L and as good as those of the ICIQ-OAB, confirming expected associations with clinical and demographic factors. The ICECAP-A was more responsive than EQ-5D-3L and ICIQ-OAB to deteriorations of clinical symptoms. Improvements in symptoms were not valued as highly as deteriorations by either ICECAP-A or EQ-5D-3L.

Conclusions

The ICECAP-A is a valid and responsive measure capturing broad emotional and practical impacts of urinary symptoms on women’s well-being and could be considered for use in economic evaluations in this context.
Appendix
Available only for authorised users
Footnotes
1
ICEPOP was a UK MRC-funded Health Services Research Collaboration programme on Investigating Choice Experiments for Preferences of Older People; it was the research programme in which the first ICECAP measure was developed.
 
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Metadata
Title
The validity and responsiveness of the ICECAP-A capability-well-being measure in women with irritative lower urinary tract symptoms
Authors
Ilias Goranitis
Joanna Coast
Hareth Al-Janabi
Pallavi Latthe
Tracy E. Roberts
Publication date
01-08-2016
Publisher
Springer International Publishing
Published in
Quality of Life Research / Issue 8/2016
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-015-1225-y

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