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At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
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Quality of Life Research
Published in: Quality of Life Research 8/2008

01-10-2008

The baseline characteristics did not differ significantly

Authors: Peter Fayers, Madeleine King

Published in: Quality of Life Research | Issue 8/2008

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Excerpt

Last week one of us (P.F.) received a message from a colleague: “Thank you for the analyses, but you forgot the P-values on Table 1”. Well, they had not been “forgotten”. While the first note in this series referred to the misleading use of P-values when reporting correlation coefficients during the evaluation of instruments [1], P-values can also be inappropriate or misleading in other situations. Herein we describe an example that is frequently encountered when reviewing manuscripts about randomised clinical trials with health-related quality of life (HRQoL) outcomes. …
Literature
1.
Fayers, P. M. (2008). The scales were highly correlated: P = 0.0001. Quality of Life Research, 17, 651–652.PubMedCrossRef
2.
Roberts, C., & Torgerson, D. J. (1999). Baseline imbalance in randomised controlled trials. BMJ (Clinical Research Ed.), 319, 185.
3.
4.
Senn, S. (2007). Statistical issues in drug development. Chichester: Wiley, ISBN 0-471-97488-9.
Metadata
Title
The baseline characteristics did not differ significantly
Authors
Peter Fayers
Madeleine King
Publication date
01-10-2008
Publisher
Springer Netherlands
Published in
Quality of Life Research / Issue 8/2008
Print ISSN: 0962-9343
Electronic ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-008-9382-x

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