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Psychiatric Quarterly
Published in: Psychiatric Quarterly 1/2020

01-03-2020 | Suicide | Original Paper

The Relationship Between Anxiety, Depression, Suicidal Ideation and Quality of Life in Patients with Rheumatoid Arthritis

Authors: Aslı Beşirli, Jülide Öncü Alptekin, Derya Kaymak, Ömer Akil Özer

Published in: Psychiatric Quarterly | Issue 1/2020

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Abstract

Rheumatoid arthritis (RA) is a chronic disease and many patients with RA experience lifelong anxiety and depression. The aim of this study is to provide an assessment of anxiety, depression, suicidal ideation, disease activity and quality of life in patients with RA. Fifty patients were included in the study. Hospital Anxiety and Depression Scale (HADS), Short Form Health Survey (SF-36), Beck Scale for Suicide Ideation (BSSI) and Disease Activity Score (DAS-28) were applied. A statistically negative correlation was found between HADS-A and HADS-D scores and all subscales of SF-36. There was a statistically negative correlation between the DAS-28 score and the subscales of the SF-36 except mental health and bodily pain. Suicidal ideation was associated with anxiety and depression and BSSI scores of patients suffering from anxiety and depression are higher than the patients not suffering from anxiety and depression. There was a statistically negative correlation between BSSI and the subscales of SF-36 excepting physical role. This study indicated that anxiety, depression, quality of life, disease activity and suicidal ideation are related to each other in patients with RA. The presence of concomitant anxiety and depression may lead to suicide and poor quality of life and may worsen the prognosis of the RA.
Literature
1.
Watad A, Bragazzi NL, Adawi M, et al. Anxiety disorder among rheumatoid arthritis patients: insights from real-life data. J Affect Disord. 2017;213:30–4.PubMed
2.
Suzuki A, Yamamoto K. From genetics to functional insights into rheumatoid arthritis. Clin Exp Rheumatol. 2015;33(4 Suppl 92):S40–3.PubMed
3.
Walsh NC, Crotti TN, Goldring SR, Gravallese EM. Rheumatic diseases: the effects of inflammation on bone. Immunol Rev. 2005;208:228–51.PubMed
4.
Nas K, Sarac AJ, Gur A, Cevik R, Altay Z, Erdal A, et al. Psychological status is associated with health related quality of life in patients with rheumatoid arthritis. J Back Musculoskelet Rehabil. 2011;24:95–100.PubMed
5.
Soósová MS, Macejová Ž, Zamboriová M, Dimunová L. Anxiety and depression in Slovak patients with rheumatoid arthritis. J Ment Health. 2017;26:21–7.PubMed
6.
Eberhardt K, Larsson BM, Nived K. Psychological reactions in patients with early rheumatoid arthritis. Patient Educ Couns. 1993;20(2–3):93–100.PubMed
7.
McWilliams LA, Clara IP, Murphy PDJ, Cox BJ, Sareen J. Associations between arthritis and a broad range of psychiatric disorders: findings from a nationally representative sample. J Pain. 2008;9:37–44.PubMed
8.
Pinho de Oliveira Ribeiro N, Rafael de Mello Schier A, Ornelas AC, Pinho de Oliveira CM, Nardi AE, Silva AC. Anxiety, depression and suicidal ideation in patients with rheumatoid arthritis in use of methotrexate, hydroxychloroquine, leflunomide and biological drugs. Compr Psychiatry. 2013;54:1185–9.PubMed
9.
Isik A, Koca SS, Ozturk A, Mermi O. Anxiety and depression in patients with rheumatoid arthritis. Clin Rheumatol. 2007;26:872–8.PubMed
10.
VanDyke MM, Parker JC, Smarr KL, Hewett JE, Johnson GE, Slaughter JR, et al. Anxiety in rheumatoid arthritis. Arthritis Rheum. 2004;51:408–12.PubMed
11.
Wittchen HU, Kessler RC, Pfister H, Lieb M. Why do people with anxiety disorders become depressed? A prospective-longitudinal community study. Acta Psychiatr Scand Suppl. 2000;406:14–23.
12.
Fiest KM, Hitchon CA, Bernstein CN, Peschken CA, Walker JR, Graff LA, et al. CIHR team “defining the burden and managing the effects of psychiatric comorbidity in chronic Immunoinflammatory disease”. Systematic review and meta-analysis of interventions for depression and anxiety in persons with rheumatoid arthritis. J Clin Rheumatol. 2017;23:425–34.PubMedPubMedCentral
13.
Matcham F, Norton S, Scott DL, Steer S, Hotopf M. Symptoms of depression and anxiety predict treatment response and long-term physical health outcomes in rheumatoid arthritis: secondary analysis of a randomized controlled trial. Rheumatology (Oxford). 2016;55:268–78.
14.
Sturgeon JA, Finan PH, Zautra AJ. Affective disturbance in rheumatoid arthritis: psychological and disease-related pathways. Nat Rev Rheumatol. 2016;12:532–42.PubMedPubMedCentral
15.
Fuller-Thomson E, Shaked Y. Factors associated with depression and suicidal ideation among individuals with arthritis or rheumatism: findings from a representative community survey. Arthritis Rheum. 2009;61:944–50.PubMed
16.
Calandre EP, Rico-Villademoros F, Slim M. Suicidal behaviors in patients with rheumatic diseases: a narrative review. Rheumatol Int. 2018;38:537–48.PubMed
17.
Treharne GJ, Lyons AC, Kitas GD. Suicidal ideation in patients with rheumatoid arthritis. Research may help identify patients at high risk. BMJ. 2000;321:1290.PubMedPubMedCentral
18.
Ang DC, Choi H, Kroenke K, Wolfe F. Comorbid depression is an independent risk factor for mortality in patients with rheumatoid arthritis. J Rheumatol. 2005;32:1013–9.PubMed
19.
Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361–70.PubMed
20.
Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30:473–83.PubMed
21.
Beck AT, Kovacs M, Weissman A. Assesment of suicide suicide intention: the scale for suicide ideation. J Consult Clin Psychology. 1979;47:343–52.
22.
van der Heijde DM, van’t Hof MA, van Riel PL, et al. Judging disease activity in clinical practice in rheumatoid arthritis: first step in the development of a disease activity score. Ann Rheum Dis. 1990;49:916–20.PubMedPubMedCentral
23.
Zhang L, Xia Y, Zhang Q, et al. The correlations of socioeconomic status, disease activity, quality of life, and depression/anxiety in Chinese patients with rheumatoid arthritis. Psychol Health Med. 2017;22:28–36.PubMed
24.
Löwe B, Willand L, Eich W, Zipfel S, Ho AD, Herzog W, et al. Psychiatric comorbidity and work disability in patients with inflammatory rheumatic diseases. Psychosom Med. 2004;66:395–402.PubMed
25.
Ho RC, Fu EH, Chua AN, Cheak AA, Mak A. Clinical and psychosocial factors associated with depression and anxiety in Singaporean patients with rheumatoid arthritis. Int J Rheum Dis. 2011;14:37–47.PubMed
26.
Abdel-Nasser AM, Abd El-Azim S, Taal E, El-Badawy SA, Rasker JJ, Valkenburg HA. Depression and depressive symptoms in rheumatoid arthritis patients: an analysis of their occurrence and determinants. Br J Rheumatol. 1998;37:391–7.PubMed
27.
Berkanovic E, Oster P, Wong WK, Bulpitt K, Clements P, Sterz M, et al. The relationship between socioeconomic status and recently diagnosed rheumatoid arthritis. Arthritis Care Res. 1996;9:257–62.PubMed
28.
Reese JB, Somers TJ, Keefe FJ, Mosley-Williams A, Lumley MA. Pain and functioning of rheumatoid arthritis patients based on marital status: is a distressed marriage preferable to no marriage? J Pain. 2010;11:958–64.PubMedPubMedCentral
29.
Wan SW, He HG, Mak A, Lahiri M, Luo N, Cheung PP, et al. Health-related quality of life and its predictors among patients with rheumatoid arthritis. Appl Nurs Res. 2016;30:176–83.PubMed
30.
Barlow JH, Cullen LA, Rowe IF. Educational preferences, psychological well-being and self-efficacy among people with rheumatoid arthritis. Patient Educ Couns. 2002;46:11–9.PubMed
31.
Margaretten M, Yelin E, Imboden J, Graf J, Barton J, Katz P, et al. Predictors of depression in a multiethnic cohort of patients with rheumatoid arthritis. Arthritis Rheum. 2009;61:1586–91.PubMedPubMedCentral
32.
Gettings L. Psychological well-being in rheumatoid arthritis: a review of the literature. Musculoskeletal Care. 2010;8:99–106.PubMed
33.
Dickens C, Jackson J, Tomenson B, Hay E, Creed F. Association of depression and rheumatoid arthritis. Psychosomatics. 2003;44:209–15.PubMed
34.
Elenkov IJ. Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being. Neurochem Int. 2008;52:40–51.PubMed
35.
Kojima M, Furukawa TA, Takahashi H, Kawai M, Nagaya T, Tokudome S. Cross-cultural validation of the Beck Depression Inventory-II in Japan. Psychiatry Res. 2002;110:291–9.PubMed
36.
Smith BW, Zautra AJ. The effects of anxiety and depression on weekly pain in women with arthritis. Pain. 2008;138:354–61.PubMedPubMedCentral
37.
Katz PP, Yelin EH. Activity loss and the onset of depressive symptoms: do some activities matter more than others? Arthritis Rheum. 2001;44:1194–202.PubMed
38.
Krol B, Sanderman R, Suurmeijer T, Doeglas D, van Rijswijk M, van Leeuwen M. Disease characteristics, level of self-esteem and psychological well-being in rheumatoid arthritis patients. Scand J Rheumatol. 1994;23:8–12.PubMed
39.
Cho SK, Kim D, Jun JB, Bae SC, Sung YK. Factors influencing quality of life (QOL) for Korean patients with rheumatoid arthritis (RA). Rheumatol Int. 2013;33:93–102.PubMed
40.
Timonen M, Viilo K, Hakko H, Särkioja T, Ylikulju M, Meyer-Rochow VB, et al. Suicides in persons suffering from rheumatoid arthritis. Rheumatology (Oxford). 2003;42:287–91.
41.
Fuller-Thomson E, Ramzan N, Baird SL. Arthritis and suicide attempts: findings from a large nationally representative Canadian survey. Rheumatol Int. 2016;36:1237–48.PubMed
42.
Shim E, Song YW, Park SH, Lee KM, Go DJ, Hahm BJ. Examining the relationship between pain catastrophizing and suicide risk in patients with rheumatic disease: the mediating role of depression, perceived social support, and perceived burdensomeness. Int J Behav Med. 2017;24:501–12.
43.
Tektonidou MG, Dasgupta A, Ward MM. Suicidal ideation among adults with arthritis: prevalence and subgroups at highest risk. Data from the 2007-2008 National Health and Nutrition Examination Survey. Arthritis Care Res (Hoboken). 2011;63:1322–33.
Metadata
Title
The Relationship Between Anxiety, Depression, Suicidal Ideation and Quality of Life in Patients with Rheumatoid Arthritis
Authors
Aslı Beşirli
Jülide Öncü Alptekin
Derya Kaymak
Ömer Akil Özer
Publication date
01-03-2020
Publisher
Springer US
Published in
Psychiatric Quarterly / Issue 1/2020
Print ISSN: 0033-2720
Electronic ISSN: 1573-6709
DOI
https://doi.org/10.1007/s11126-019-09680-x

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