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01-03-2018 | Original Paper

Elevated Plasma S100B, Psychotic Symptoms, and Cognition in Schizophrenia

Authors: Huiqiong Deng, Ramandeep S. Kahlon, Satyajit Mohite, Pooja A. Amin, Giovana Zunta-Soares, Gabriela D. Colpo, Laura Stertz, Gabriel R. Fries, Consuelo Walss-Bass, Jair C. Soares, Olaoluwa O. Okusaga

Published in: Psychiatric Quarterly | Issue 1/2018

Abstract

S100B is a calcium binding protein mainly produced by glial cells. Previous studies have shown elevated levels of S100B in patients with schizophrenia. We measured S100B levels in fasting plasma of 39 patients with schizophrenia and 19 adult healthy controls. We used linear regression to compare S100B between patients and controls. In patients only, we also investigated the relationship between S100B levels and psychotic symptoms (assessed by the Positive and Negative Syndrome Scale), and cognitive function (assessed by the NIH Toolbox Cognition Battery), respectively by calculating Pearson’s correlation coefficients. Mean plasma S100B was significantly higher in the patient group than in the control group. There were no significant correlations between plasma S100B and psychotic symptoms or cognition.

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Title: Elevated Plasma S100B, Psychotic Symptoms, and Cognition in Schizophrenia
Authors: Huiqiong Deng
Ramandeep S. Kahlon
Satyajit Mohite
Pooja A. Amin
Giovana Zunta-Soares
Gabriela D. Colpo
Laura Stertz
Gabriel R. Fries
Consuelo Walss-Bass
Jair C. Soares
Olaoluwa O. Okusaga
Publication date: 01-03-2018
Publisher: Springer US
Published in: Psychiatric Quarterly / Issue 1/2018
Print ISSN: 0033-2720
Electronic ISSN: 1573-6709
DOI: https://doi.org/10.1007/s11126-017-9514-y

ACC 2024 Congress

Springer Medicine

Elevated Plasma S100B, Psychotic Symptoms, and Cognition in Schizophrenia

Abstract

ACC 2024 Congress

Springer Medicine

Abstract

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