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Psychiatric Quarterly
Published in: Psychiatric Quarterly 3/2016

Open Access 01-09-2016 | Original Paper

Can Psychological, Social and Demographical Factors Predict Clinical Characteristics Symptomatology of Bipolar Affective Disorder and Schizophrenia?

Authors: Malgorzata Maciukiewicz, PhD, Joanna Pawlak, PhD, MD, Pawel Kapelski, PhD, MD, Magdalena Łabędzka, MD, Maria Skibinska, PhD, Dorota Zaremba, Anna Leszczynska-Rodziewicz, PhD, MD, Monika Dmitrzak-Weglarz, PhD, Joanna Hauser, PhD, MD

Published in: Psychiatric Quarterly | Issue 3/2016

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Abstract

Schizophrenia (SCH) is a complex, psychiatric disorder affecting 1 % of population. Its clinical phenotype is heterogeneous with delusions, hallucinations, depression, disorganized behaviour and negative symptoms. Bipolar affective disorder (BD) refers to periodic changes in mood and activity from depression to mania. It affects 0.5–1.5 % of population. Two types of disorder (type I and type II) are distinguished by severity of mania episodes. In our analysis, we aimed to check if clinical and demographical characteristics of the sample are predictors of symptom dimensions occurrence in BD and SCH cases. We included total sample of 443 bipolar and 439 schizophrenia patients. Diagnosis was based on DSM-IV criteria using Structured Clinical Interview for DSM-IV. We applied regression models to analyse associations between clinical and demographical traits from OPCRIT and symptom dimensions. We used previously computed dimensions of schizophrenia and bipolar affective disorder as quantitative traits for regression models. Male gender seemed protective factor for depression dimension in schizophrenia and bipolar disorder sample. Presence of definite psychosocial stressor prior disease seemed risk factor for depressive and suicidal domain in BD and SCH. OPCRIT items describing premorbid functioning seemed related with depression, positive and disorganised dimensions in schizophrenia and psychotic in BD. We proved clinical and demographical characteristics of the sample are predictors of symptom dimensions of schizophrenia and bipolar disorder. We also saw relation between clinical dimensions and course of disorder and impairment during disorder.
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Metadata
Title
Can Psychological, Social and Demographical Factors Predict Clinical Characteristics Symptomatology of Bipolar Affective Disorder and Schizophrenia?
Authors
Malgorzata Maciukiewicz, PhD
Joanna Pawlak, PhD, MD
Pawel Kapelski, PhD, MD
Magdalena Łabędzka, MD
Maria Skibinska, PhD
Dorota Zaremba
Anna Leszczynska-Rodziewicz, PhD, MD
Monika Dmitrzak-Weglarz, PhD
Joanna Hauser, PhD, MD
Publication date
01-09-2016
Publisher
Springer US
Published in
Psychiatric Quarterly / Issue 3/2016
Print ISSN: 0033-2720
Electronic ISSN: 1573-6709
DOI
https://doi.org/10.1007/s11126-015-9405-z

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