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Published in: Neuropsychology Review 1/2012

01-03-2012 | Review

Neuropsychological Sequelae of PTSD and TBI Following War Deployment among OEF/OIF Veterans

Authors: Sara Dolan, Sarah Martindale, Jennifer Robinson, Nathan A. Kimbrel, Eric C. Meyer, Marc I. Kruse, Sandra B. Morissette, Keith A. Young, Suzy Bird Gulliver

Published in: Neuropsychology Review | Issue 1/2012

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Abstract

Posttraumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) are highly prevalent among Veterans of the conflicts in Iraq and Afghanistan. These conditions are associated with common and unique neuropsychological and neuroanatomical changes. This review synthesizes neuropsychological and neuroimaging studies for both of these disorders and studies examining their co-occurrence. Recommendations for future research, including use of combined neuropsychological and advanced neuroimaging techniques to study these disorders alone and in concert, are presented. It is clear from the dearth of literature that addiitonal studies are required to examine and understand the impact of specific factors on neurocognitive outcome. Of particular relevance are temporal relationships between PTSD and mTBI, risk and resilience factors associated with both disorders and their co-occurrence, and mTBI-specific factors such as time since injury and severity of injury, utilizing comprehensive, yet targeted cognitive tasks.
Footnotes
1
Hemosiderin deposits are iron deposits thought to be left behind after a bleed in the brain. Because this iron is magnetic, it can be detected via MRI. Suceptibility Weighted Imaging (SWI) or other field-dependent relaxivity imaging also potentially could be used to detect microbleeds (TBIlaw.com).
 
Literature
go back to reference Abutalebi, J., Doering, L. B., Della Rosa, P. A., & Mariën, P. (2008). Structural and functional neuroimaging in neuropsychology: A concise overview. In P. Mariën & J. Abutalebi (Eds.), Neuropsychological research: A review (pp. 51–72). New York, NY US: Psychology Press. Abutalebi, J., Doering, L. B., Della Rosa, P. A., & Mariën, P. (2008). Structural and functional neuroimaging in neuropsychology: A concise overview. In P. Mariën & J. Abutalebi (Eds.), Neuropsychological research: A review (pp. 51–72). New York, NY US: Psychology Press.
go back to reference American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders, 4th Edition Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association.CrossRef American Psychiatric Association. (2000). Diagnostic and Statistical Manual of Mental Disorders, 4th Edition Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association.CrossRef
go back to reference Armistead-Jehle, P. (2010). Symptom validity test performance in U.S. veterans referred for evaluation of mild TBI. Applied Neurpsychology, 17, 52–59.CrossRef Armistead-Jehle, P. (2010). Symptom validity test performance in U.S. veterans referred for evaluation of mild TBI. Applied Neurpsychology, 17, 52–59.CrossRef
go back to reference Bar-Haim, Y., Lamy, D., Pergamin, L., Bakermans-Kranenburg, M. J., & van IJzendoom, M. H. (2007). Thereat related attention bias in anxious and nonanxious individuals: A meta-analytic study. Psychological Bulletin, 133, 1–12.PubMedCrossRef Bar-Haim, Y., Lamy, D., Pergamin, L., Bakermans-Kranenburg, M. J., & van IJzendoom, M. H. (2007). Thereat related attention bias in anxious and nonanxious individuals: A meta-analytic study. Psychological Bulletin, 133, 1–12.PubMedCrossRef
go back to reference Barrett, D. H., Green, M. L., Morris, R., Giles, W. H., & Croft, J. B. (1996). Cognitive functioning and posttraumatic stress disorder. The American Journal of Psychiatry, 259, 2701–2707. Barrett, D. H., Green, M. L., Morris, R., Giles, W. H., & Croft, J. B. (1996). Cognitive functioning and posttraumatic stress disorder. The American Journal of Psychiatry, 259, 2701–2707.
go back to reference Beckham, J. C., Crawford, A. L., & Feldman, M. E. (1998). Trail Making Test performance in Vietnam combat veterans with and without posttraumatic stress disorder. Journal of Traumatic Stress, 11, 811–819.PubMedCrossRef Beckham, J. C., Crawford, A. L., & Feldman, M. E. (1998). Trail Making Test performance in Vietnam combat veterans with and without posttraumatic stress disorder. Journal of Traumatic Stress, 11, 811–819.PubMedCrossRef
go back to reference Belanger, H. G., Curtiss, G., Demery, J. A., Lebowitz, B. K., & Vanderploeg, R. D. (2005). Factors moderating neuropsychological outcomes following mild traumatic brain injury: A meta-analysis. Journal of the International Neuropsychological Society, 11, 215–227.PubMedCrossRef Belanger, H. G., Curtiss, G., Demery, J. A., Lebowitz, B. K., & Vanderploeg, R. D. (2005). Factors moderating neuropsychological outcomes following mild traumatic brain injury: A meta-analysis. Journal of the International Neuropsychological Society, 11, 215–227.PubMedCrossRef
go back to reference Belanger, H. G., Uomoto, J. M., & Vanderploeg, R. D. (2009). The Veterans Health Administration’s (VHA’s) Polytrauma System of Care for mild traumatic brain injury: Costs, benefits, and controversies. The Journal of Head Trauma Rehabilitation, 24(1), 4–13.PubMedCrossRef Belanger, H. G., Uomoto, J. M., & Vanderploeg, R. D. (2009). The Veterans Health Administration’s (VHA’s) Polytrauma System of Care for mild traumatic brain injury: Costs, benefits, and controversies. The Journal of Head Trauma Rehabilitation, 24(1), 4–13.PubMedCrossRef
go back to reference Binder, L. M., Rohling, M. L., & Larrabee, G. J. (1997). A review of mild head trauma, Part I: Meta-analytic review of neuropsychological studies. Journal of Clinical and Experimental Neuropsychology, 19, 421–431.PubMedCrossRef Binder, L. M., Rohling, M. L., & Larrabee, G. J. (1997). A review of mild head trauma, Part I: Meta-analytic review of neuropsychological studies. Journal of Clinical and Experimental Neuropsychology, 19, 421–431.PubMedCrossRef
go back to reference Bremner, J. D., Randall, P. R., Scott, T. M., Bronen, R. A., Delaney, R. C., Seibyl, J. P., et al. (1995). MRI-based measurement of hippocampal volume in posttraumatic stress disorder. American Journal of Psychiatry, 152, 973–981. Bremner, J. D., Randall, P. R., Scott, T. M., Bronen, R. A., Delaney, R. C., Seibyl, J. P., et al. (1995). MRI-based measurement of hippocampal volume in posttraumatic stress disorder. American Journal of Psychiatry, 152, 973–981.
go back to reference Brenner, L. A., Ladley-O’Brian, S. E., Harwood, J. E. F., Filley, C. M., Kelly, J. P., Homaifar, B. Y., et al. (2009). An Exploratory Study of Neuroimaging, Neurologic, and Neuropsychological findings in Veterans with Traumatic Brain Injury and/or Posttraumatic Stress Disorder. Military Medicine, 174(4), 347–352.PubMed Brenner, L. A., Ladley-O’Brian, S. E., Harwood, J. E. F., Filley, C. M., Kelly, J. P., Homaifar, B. Y., et al. (2009). An Exploratory Study of Neuroimaging, Neurologic, and Neuropsychological findings in Veterans with Traumatic Brain Injury and/or Posttraumatic Stress Disorder. Military Medicine, 174(4), 347–352.PubMed
go back to reference Brenner, L. A., Terrio, H., Homaifar, B. Y., Gutierrez, P. M., Staves, P. J., Harwood, J. E. F., . . . Warden, D. (2010). Neuropsychological test performance in soldiers with blast-related mild TBI. Neuropsychology, 24(2), 160–167. doi:10.1037/a0017966 Brenner, L. A., Terrio, H., Homaifar, B. Y., Gutierrez, P. M., Staves, P. J., Harwood, J. E. F., . . . Warden, D. (2010). Neuropsychological test performance in soldiers with blast-related mild TBI. Neuropsychology, 24(2), 160–167. doi:10.​1037/​a0017966
go back to reference Brewin, C., Andrews, B., & Valentine, J. (2000). Meta-analysis of risk factors for PTSD in trauma-exposed adults. Journal of Consulting and Clinical Psychology, 68, 748–766.PubMedCrossRef Brewin, C., Andrews, B., & Valentine, J. (2000). Meta-analysis of risk factors for PTSD in trauma-exposed adults. Journal of Consulting and Clinical Psychology, 68, 748–766.PubMedCrossRef
go back to reference Brewin, C. R., Kleiner, J. S., Vasterling, J. J., & Field, A. P. (2007). Memory for emotionally neutral information in posttraumatic stress disorder: A meta—analytic investigation. Journal of Abnormal Psychology, 116(3), 448–463.PubMedCrossRef Brewin, C. R., Kleiner, J. S., Vasterling, J. J., & Field, A. P. (2007). Memory for emotionally neutral information in posttraumatic stress disorder: A meta—analytic investigation. Journal of Abnormal Psychology, 116(3), 448–463.PubMedCrossRef
go back to reference Buckley, T. C., Blanchard, E. B., & Neill, W. T. (2000). Information processing and PTSD: A review of the empirical literature. Clinical Psychology Review, 28, 1041–1065.CrossRef Buckley, T. C., Blanchard, E. B., & Neill, W. T. (2000). Information processing and PTSD: A review of the empirical literature. Clinical Psychology Review, 28, 1041–1065.CrossRef
go back to reference Buzsáki, G., Chen, L. S., & Gage, F. H. (1990). Spatial organization of physiological activity in the hippocampal region: relevance to memory formation. Progress in Brain Research, 83, 257–268.PubMedCrossRef Buzsáki, G., Chen, L. S., & Gage, F. H. (1990). Spatial organization of physiological activity in the hippocampal region: relevance to memory formation. Progress in Brain Research, 83, 257–268.PubMedCrossRef
go back to reference Cameron, O. G. (2001). Interoception: The inside story—A model for psychosomatic processes. Psychosomatic Medicine, 63, 697–710.PubMed Cameron, O. G. (2001). Interoception: The inside story—A model for psychosomatic processes. Psychosomatic Medicine, 63, 697–710.PubMed
go back to reference Campbell, T. A., Nelson, L. A., Lumpkin, R., Yoash-Gantz, R. E., Pickett, T. C., & McCornick, C. L. (2009). Neuropsychological measures of processing speed and executive functioning in combat Veterans with PTSD, TBI, and comorbid TBI/PTSD. Psychiatric Annals, 39(8), 796–803.CrossRef Campbell, T. A., Nelson, L. A., Lumpkin, R., Yoash-Gantz, R. E., Pickett, T. C., & McCornick, C. L. (2009). Neuropsychological measures of processing speed and executive functioning in combat Veterans with PTSD, TBI, and comorbid TBI/PTSD. Psychiatric Annals, 39(8), 796–803.CrossRef
go back to reference Carlson, K. F., Kehle, S. M., Meis, L., Greer, N., MacDonald, R., Rutks, I., Sayer, N. A., Dobscha, S. K., & Wilt, T. J. (2011). Prevalence, assessment, and treatment of mild traumatic brain injury and posttraumatic stress disorder: A systematic review of the evidence. The Journal of Head Trauma Rehabilitation, 26, 103–115.PubMedCrossRef Carlson, K. F., Kehle, S. M., Meis, L., Greer, N., MacDonald, R., Rutks, I., Sayer, N. A., Dobscha, S. K., & Wilt, T. J. (2011). Prevalence, assessment, and treatment of mild traumatic brain injury and posttraumatic stress disorder: A systematic review of the evidence. The Journal of Head Trauma Rehabilitation, 26, 103–115.PubMedCrossRef
go back to reference Cassidy, J. D., Carroll, L. J., Peloso, P. M., Borg, J., von Holst, H., Holm, L., et al. (2004). Incidence, risk factors and prevention of mild traumatic brain injury: Results of the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. Journal of Rehabilitative Medicine, 36(43), 28–60.CrossRef Cassidy, J. D., Carroll, L. J., Peloso, P. M., Borg, J., von Holst, H., Holm, L., et al. (2004). Incidence, risk factors and prevention of mild traumatic brain injury: Results of the WHO Collaborating Centre Task Force on Mild Traumatic Brain Injury. Journal of Rehabilitative Medicine, 36(43), 28–60.CrossRef
go back to reference Constans, J. I. (2005). Information-processing biases in PTSD. In J. J. Vasterling & C. R. Brewin (Eds.), Neuropsychology of PTSD: Biological, cognitive, and clinical perspectives (pp. 105–130). New York: Guilford Press. Constans, J. I. (2005). Information-processing biases in PTSD. In J. J. Vasterling & C. R. Brewin (Eds.), Neuropsychology of PTSD: Biological, cognitive, and clinical perspectives (pp. 105–130). New York: Guilford Press.
go back to reference Crowell, T. A., Kieffer, K. M., Siders, C. A., & Vanderploeg, R. D. (2002). Neuropsychological findings in combat-related posttraumatic stress disorder. Clinical Neuropsychologist, 16(3), 310. Crowell, T. A., Kieffer, K. M., Siders, C. A., & Vanderploeg, R. D. (2002). Neuropsychological findings in combat-related posttraumatic stress disorder. Clinical Neuropsychologist, 16(3), 310.
go back to reference Danckwerts, A., & Leathem, J. (2003). Questioning the link between PTSD and cognitive dysfunction. Neuropsychology Review, 13, 221–235.PubMedCrossRef Danckwerts, A., & Leathem, J. (2003). Questioning the link between PTSD and cognitive dysfunction. Neuropsychology Review, 13, 221–235.PubMedCrossRef
go back to reference Demery, J. A., Larson, M. J., Dixit, N. K., Bauer, R. M., & Perlstein, W. M. (2010). Operational characteristics of executive functioning following traumatic brain injury. The Clinical Neuropsychologist, 24, 1292–1308.PubMedCrossRef Demery, J. A., Larson, M. J., Dixit, N. K., Bauer, R. M., & Perlstein, W. M. (2010). Operational characteristics of executive functioning following traumatic brain injury. The Clinical Neuropsychologist, 24, 1292–1308.PubMedCrossRef
go back to reference Dikmen, S., Machamer, J., Fann, J. R., & Temkin, N. R. (2010). Rates of symptom reporting following traumatic brain injury. Journal of the International Neuropsychological Society, 16, 401–411.PubMedCrossRef Dikmen, S., Machamer, J., Fann, J. R., & Temkin, N. R. (2010). Rates of symptom reporting following traumatic brain injury. Journal of the International Neuropsychological Society, 16, 401–411.PubMedCrossRef
go back to reference Fox, P. T., & Lancaster, J. L. (2002). Opinion: Mapping context and content: the BrainMap model. Nature Reviews Neuroscience, 3(4), 319–321.PubMedCrossRef Fox, P. T., & Lancaster, J. L. (2002). Opinion: Mapping context and content: the BrainMap model. Nature Reviews Neuroscience, 3(4), 319–321.PubMedCrossRef
go back to reference French, L. M. (2010). Military traumatic brain injury: An examination of important differences. Annals of the New York Academy of Sciences, 1208, 38–45.PubMedCrossRef French, L. M. (2010). Military traumatic brain injury: An examination of important differences. Annals of the New York Academy of Sciences, 1208, 38–45.PubMedCrossRef
go back to reference Frenchman, K. A., Fox, A. M., & Mayberry, M. T. (2005). Neuropsychological studies of mild traumatic brain injury: A meta-analytic review of research since 1995. Journal of Clinical and Experimental Neuropsychology, 27, 334–351.CrossRef Frenchman, K. A., Fox, A. M., & Mayberry, M. T. (2005). Neuropsychological studies of mild traumatic brain injury: A meta-analytic review of research since 1995. Journal of Clinical and Experimental Neuropsychology, 27, 334–351.CrossRef
go back to reference Gale, C. R., Deary, I. J., Boyle, S. H., Barefott, J., Mortensen, L. H., & Batty, G. D. (2008). Cognitive ability in early adulthood and risk of five specific disorders in middle age: The Vietnam experience study. Archives of General Psychiatry, 65, 1410–1418.PubMedCrossRef Gale, C. R., Deary, I. J., Boyle, S. H., Barefott, J., Mortensen, L. H., & Batty, G. D. (2008). Cognitive ability in early adulthood and risk of five specific disorders in middle age: The Vietnam experience study. Archives of General Psychiatry, 65, 1410–1418.PubMedCrossRef
go back to reference Gil, T., Calev, A., Greenberg, D., Kugelmass, S., & Lerer, B. (1990). Cognitive functioning in post-traumatic stress disorder. Journal of Traumatic Stress, 3, 29–45.CrossRef Gil, T., Calev, A., Greenberg, D., Kugelmass, S., & Lerer, B. (1990). Cognitive functioning in post-traumatic stress disorder. Journal of Traumatic Stress, 3, 29–45.CrossRef
go back to reference Gilbertson, M. W., Gurvits, T. V., Lasko, N. B., Orr, S. P., & Pitman, R. K. (2001). Multivariate assessment of explicit memory functioning in combat veterans with posttraumatic stress disorder. Journal of Traumatic Stress, 14, 413–432.PubMedCrossRef Gilbertson, M. W., Gurvits, T. V., Lasko, N. B., Orr, S. P., & Pitman, R. K. (2001). Multivariate assessment of explicit memory functioning in combat veterans with posttraumatic stress disorder. Journal of Traumatic Stress, 14, 413–432.PubMedCrossRef
go back to reference Gilbertson, M., Paulus, L., Williston, S., Gurvits, T., Lasko, N., Pitman, R., et al. (2006). Neurocognitive function in monozygotic twins discordant for combat exposure: Relationship to posttraumatic stress disorder. Journal of Abnormal Psychology, 115, 484–495.PubMedCrossRef Gilbertson, M., Paulus, L., Williston, S., Gurvits, T., Lasko, N., Pitman, R., et al. (2006). Neurocognitive function in monozygotic twins discordant for combat exposure: Relationship to posttraumatic stress disorder. Journal of Abnormal Psychology, 115, 484–495.PubMedCrossRef
go back to reference Gurvits, T. V., Lasko, N. B., Schacter, S. C., Kuhne, A. A., Orr, S. P., & Pitman, R. K. (1993). Neurological status of Vietnam veterans with chronic posttraumatic stress disorder. The Journal of Neuropsychiatry and Clinical Neurosciences, 5, 183–188.PubMed Gurvits, T. V., Lasko, N. B., Schacter, S. C., Kuhne, A. A., Orr, S. P., & Pitman, R. K. (1993). Neurological status of Vietnam veterans with chronic posttraumatic stress disorder. The Journal of Neuropsychiatry and Clinical Neurosciences, 5, 183–188.PubMed
go back to reference Hartlage, L. C., Durant-Wilson, D., & Patch, P. C. (2001). Persistent neurobehavioral problems following mild traumatic brain injury. Archives of Clinical Neuropsychology, 16, 561–570.PubMed Hartlage, L. C., Durant-Wilson, D., & Patch, P. C. (2001). Persistent neurobehavioral problems following mild traumatic brain injury. Archives of Clinical Neuropsychology, 16, 561–570.PubMed
go back to reference Hayes, J. P., LaBar, K. S., McCarthy, G., Selgrade, E., Nasser, J., Dolcos, F., & Morey, R. A. (2011). Reduced hippocampal and amygdala activity predicts memory distortions for trauma reminders in combat-related PTSD. Journal of Psychiatric Research, 45(5), 660–669. Hayes, J. P., LaBar, K. S., McCarthy, G., Selgrade, E., Nasser, J., Dolcos, F., & Morey, R. A. (2011). Reduced hippocampal and amygdala activity predicts memory distortions for trauma reminders in combat-related PTSD. Journal of Psychiatric Research, 45(5), 660–669.
go back to reference Hedges, D. W., & Woon, F. L. (2010). Premordid brain volume estimates and reduced total brain volume in adults exposed to truama with or without posttraumatic stress disorder: a meta-analysis. Cognitive Behavioral Neurology, 23(2), 124–129. Hedges, D. W., & Woon, F. L. (2010). Premordid brain volume estimates and reduced total brain volume in adults exposed to truama with or without posttraumatic stress disorder: a meta-analysis. Cognitive Behavioral Neurology, 23(2), 124–129.
go back to reference Heilbronner, R. L., Sweet, J. J., Morgan, J. E., Larrabee, G. J., Millis, S. R., & Participants, C. (2009). American Academy of Clinical Neuropsychology consensus conference statement on the neuropsychological assessment of effort, response bias, and malingering. The Clinical Neuropsychologist, 23, 1093–1129.PubMedCrossRef Heilbronner, R. L., Sweet, J. J., Morgan, J. E., Larrabee, G. J., Millis, S. R., & Participants, C. (2009). American Academy of Clinical Neuropsychology consensus conference statement on the neuropsychological assessment of effort, response bias, and malingering. The Clinical Neuropsychologist, 23, 1093–1129.PubMedCrossRef
go back to reference Hoge, C., Castro, C., Messer, S., McGurk, D., Cotting, D., & Koffman, R. (2004). Combat duty in Iraq and Afghanistan, mental health care problems, and barriers to care. New England J of Medicine., 351, 13–22.CrossRef Hoge, C., Castro, C., Messer, S., McGurk, D., Cotting, D., & Koffman, R. (2004). Combat duty in Iraq and Afghanistan, mental health care problems, and barriers to care. New England J of Medicine., 351, 13–22.CrossRef
go back to reference Hoge, C. W., McGurk, D., Thomas, J., Cox, A. L., Engel, C. C., & Castro, C. A. (2008). Mild traumatic brain injury in U.S. soldiers returning from Iraq. The New England Journal of Medicine, 358(5), 453–463. doi:10.1056/NEJMoa072972.PubMedCrossRef Hoge, C. W., McGurk, D., Thomas, J., Cox, A. L., Engel, C. C., & Castro, C. A. (2008). Mild traumatic brain injury in U.S. soldiers returning from Iraq. The New England Journal of Medicine, 358(5), 453–463. doi:10.​1056/​NEJMoa072972.PubMedCrossRef
go back to reference Horner, M. D., & Hamner, M. B. (2002). Neurocognitive Functioning in Posttraumatic Stress Disorder. [Article]. Neuropsychology Review, 12(1), 15–30.PubMedCrossRef Horner, M. D., & Hamner, M. B. (2002). Neurocognitive Functioning in Posttraumatic Stress Disorder. [Article]. Neuropsychology Review, 12(1), 15–30.PubMedCrossRef
go back to reference Iverson, G. L. (2005). Outcome from mild traumatic brain injury. Current Opinion in Psychiatry, 18, 301–317.PubMedCrossRef Iverson, G. L. (2005). Outcome from mild traumatic brain injury. Current Opinion in Psychiatry, 18, 301–317.PubMedCrossRef
go back to reference Johnsen, G. E., & Asbjørnsen, A. E. (2008). Consistent impaired verbal memory in PTSD: a meta-analysis. Journal of Affective Disorders, 111, 74–82.PubMedCrossRef Johnsen, G. E., & Asbjørnsen, A. E. (2008). Consistent impaired verbal memory in PTSD: a meta-analysis. Journal of Affective Disorders, 111, 74–82.PubMedCrossRef
go back to reference Kandel, E.R., Schwartz, J.H., & Jessell, T.M. (1991). Principles of Neural Science. McGraw Hill. Kandel, E.R., Schwartz, J.H., & Jessell, T.M. (1991). Principles of Neural Science. McGraw Hill.
go back to reference Karl, A., Schaefer, M., Malta, L. S., Dörfel, D., Rohleder, N., & Werner, A. (2006). A meta-analysis of structural brain abnormalities in PTSD. Neuroscience & Biobehavioral Reviews, 30(7), 1004–1031. doi:10.1016/j.neubiorev.2006.03.004. Karl, A., Schaefer, M., Malta, L. S., Dörfel, D., Rohleder, N., & Werner, A. (2006). A meta-analysis of structural brain abnormalities in PTSD. Neuroscience & Biobehavioral Reviews, 30(7), 1004–1031. doi:10.​1016/​j.​neubiorev.​2006.​03.​004.
go back to reference Kimble, M. (2008). Neurobiological models in posttraumatic stress disorder: effects on public perception and patient care. Journal of Psychological Trauma, 6(4), 57–78. Kimble, M. (2008). Neurobiological models in posttraumatic stress disorder: effects on public perception and patient care. Journal of Psychological Trauma, 6(4), 57–78.
go back to reference Kitayama, N., Vaccarino, V., Kutner, M., Weiss, P., & Bremner, J. D. (2005). Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis. Journal of Affective Disorder, 88, 79–86. Kitayama, N., Vaccarino, V., Kutner, M., Weiss, P., & Bremner, J. D. (2005). Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis. Journal of Affective Disorder, 88, 79–86.
go back to reference Koenen, K.C., Driver, K.L., Oscar-Berman, M., Wolfe, J., Folsm, S, …& Schlesinger, L. (2001). Measures of prefrontal system dysfunction in post-traumatic stress disorder. Brain and Cognition, 45, 64–78. Koenen, K.C., Driver, K.L., Oscar-Berman, M., Wolfe, J., Folsm, S, …& Schlesinger, L. (2001). Measures of prefrontal system dysfunction in post-traumatic stress disorder. Brain and Cognition, 45, 64–78.
go back to reference Knutson, B., Westdorp, A., Kaiser, E., & Hommer, D. (2000). FMRI visualization of brain activity during a monetary incentive delay task. NeuroImage, 12, 20–27.PubMedCrossRef Knutson, B., Westdorp, A., Kaiser, E., & Hommer, D. (2000). FMRI visualization of brain activity during a monetary incentive delay task. NeuroImage, 12, 20–27.PubMedCrossRef
go back to reference Kraus, M. F., Susmaras, T., Caughlin, B. P., Walker, C. J., Sweeney, J. A., & Little, D. M. (2007). White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. Brain, 130(Pt 10), 2508–2519.PubMedCrossRef Kraus, M. F., Susmaras, T., Caughlin, B. P., Walker, C. J., Sweeney, J. A., & Little, D. M. (2007). White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study. Brain, 130(Pt 10), 2508–2519.PubMedCrossRef
go back to reference Kremen, W., Koenen, K.C., Boake, C., Purcell, S., Eisen, S.A., Franz, C. E., … & Lyons, M.J. (2007). Pretrauma cognitive ability and risk for posttraumatic stress disorder. Archives of General Psychiatry, 64, 361–368. Kremen, W., Koenen, K.C., Boake, C., Purcell, S., Eisen, S.A., Franz, C. E., … & Lyons, M.J. (2007). Pretrauma cognitive ability and risk for posttraumatic stress disorder. Archives of General Psychiatry, 64, 361–368.
go back to reference Laird, A. R., Eickhoff, S. B., Kurth, F., Fox, P. M., Uecker, A. M., Turner, J. A., et al. (2009). ALE meta-analysis workflows via the BrainMap database: Progress towards a probabilistic functional brain atlas. Frontiers in Neuroinformatics, 3, 1–11.CrossRef Laird, A. R., Eickhoff, S. B., Kurth, F., Fox, P. M., Uecker, A. M., Turner, J. A., et al. (2009). ALE meta-analysis workflows via the BrainMap database: Progress towards a probabilistic functional brain atlas. Frontiers in Neuroinformatics, 3, 1–11.CrossRef
go back to reference Laird, A. R., Lancaster, J. L., & Fox, P. T. (2005). BrainMap: the social evolution of a human brain mapping database. Neuroinformatics, 3(1), 65–78.PubMedCrossRef Laird, A. R., Lancaster, J. L., & Fox, P. T. (2005). BrainMap: the social evolution of a human brain mapping database. Neuroinformatics, 3(1), 65–78.PubMedCrossRef
go back to reference Levin, H. S., Wilde, E., Troyanskaya, M., Petersen, N. J., Scheibel, R., Newsome, M., et al. (2010). Diffusion tensor imaging of mild to moderate blast-related traumatic brain injury and its sequelae. Journal of Neurotrauma, 27, 683–694.PubMedCrossRef Levin, H. S., Wilde, E., Troyanskaya, M., Petersen, N. J., Scheibel, R., Newsome, M., et al. (2010). Diffusion tensor imaging of mild to moderate blast-related traumatic brain injury and its sequelae. Journal of Neurotrauma, 27, 683–694.PubMedCrossRef
go back to reference Lezak, M. (1995). Neuropsychological assessment (3rd ed.). New York: Oxford University Press. Lezak, M. (1995). Neuropsychological assessment (3rd ed.). New York: Oxford University Press.
go back to reference Litz, B.T., Weathers, F.W., Monaco, V., Herman, D.S., Wulfsohn, M., … Keane, T.M. (1996). Attention, arousal, and memory in posttraumatic stress disorder. Journal of Traumatic Stress, 9, 497–520. Litz, B.T., Weathers, F.W., Monaco, V., Herman, D.S., Wulfsohn, M., … Keane, T.M. (1996). Attention, arousal, and memory in posttraumatic stress disorder. Journal of Traumatic Stress, 9, 497–520.
go back to reference Mac Donald, C. L., Johnson, A. M., Cooper, D., Nelson, E. C., Werner, N. J., Shimony, J. S., et al. (2011). Detection of blast-related traumatic brain injury in U. S. military personnel. The New England Journal of Medicine, 364(22), 2091–2100.PubMedCrossRef Mac Donald, C. L., Johnson, A. M., Cooper, D., Nelson, E. C., Werner, N. J., Shimony, J. S., et al. (2011). Detection of blast-related traumatic brain injury in U. S. military personnel. The New England Journal of Medicine, 364(22), 2091–2100.PubMedCrossRef
go back to reference Macklin, M. L., Metzger, L. P., Litz, B. T., McNally, R. J., Lasko, N. B., Orr, S. P., & Pitman, R. K. (1998). Lower Precombat Intelligence Is a Risk Factor for Posttraumatic Stress Disorder. Journal of Consulting and Clinical Psychology, 66, 323–326.PubMedCrossRef Macklin, M. L., Metzger, L. P., Litz, B. T., McNally, R. J., Lasko, N. B., Orr, S. P., & Pitman, R. K. (1998). Lower Precombat Intelligence Is a Risk Factor for Posttraumatic Stress Disorder. Journal of Consulting and Clinical Psychology, 66, 323–326.PubMedCrossRef
go back to reference Marx, B., Brailey, K., Proctor, S., MacDonald, H., Graefe, A., Amorso, P., & Vasterling, J. (2009). Association of time since deployment, combat intensity, and posttraumatic stress symptoms with neuropsychological outcomes following Iraq war deployment. Archives of General Psychiatry, 66, 996–1004.PubMedCrossRef Marx, B., Brailey, K., Proctor, S., MacDonald, H., Graefe, A., Amorso, P., & Vasterling, J. (2009). Association of time since deployment, combat intensity, and posttraumatic stress symptoms with neuropsychological outcomes following Iraq war deployment. Archives of General Psychiatry, 66, 996–1004.PubMedCrossRef
go back to reference Marx, B. P., Doron-Lamarca, S., Proctor, S. P., & Vasterling, P. P. (2009). The influence of pre-deployment neurocgnitive functioning on post-deployment PTSD symptom outcomes among Iraq-deployed Army Soldiers. Journal of the International Neuropsychological Society, 15, 840–852.PubMedCrossRef Marx, B. P., Doron-Lamarca, S., Proctor, S. P., & Vasterling, P. P. (2009). The influence of pre-deployment neurocgnitive functioning on post-deployment PTSD symptom outcomes among Iraq-deployed Army Soldiers. Journal of the International Neuropsychological Society, 15, 840–852.PubMedCrossRef
go back to reference Mayer, A. R., Teshiba, T. M., Franco, A. R., Ling, J., Shane, M. S., Stephen, J. M., & Jung, R. E. (2011). Modeling conflict and error in the medial frontal cortex. Human Brain Mapping. Mayer, A. R., Teshiba, T. M., Franco, A. R., Ling, J., Shane, M. S., Stephen, J. M., & Jung, R. E. (2011). Modeling conflict and error in the medial frontal cortex. Human Brain Mapping.
go back to reference McFarlane, A. C., Weber, D. L., & Clark, C. R. (1993). Abnormal stimulus processing in post-traumatic stress disorder. Biological Psychiatry, 5, 817–826. McFarlane, A. C., Weber, D. L., & Clark, C. R. (1993). Abnormal stimulus processing in post-traumatic stress disorder. Biological Psychiatry, 5, 817–826.
go back to reference McKittrick, C. R., Magariños, A. M., Blanchard, D. C., Blanchard, R. J., McEwen, B. S., & Sakai, R. R. (200). Chronic social stress reduces dendritic arbors in CA3 of hippocampus and decreases binding to serotonin transporter sites. Synapse, 36(2), 85–94. McKittrick, C. R., Magariños, A. M., Blanchard, D. C., Blanchard, R. J., McEwen, B. S., & Sakai, R. R. (200). Chronic social stress reduces dendritic arbors in CA3 of hippocampus and decreases binding to serotonin transporter sites. Synapse, 36(2), 85–94.
go back to reference McNally, R. J., & Shin, L. M. (1995). Association of intelligence with severity of posttraumatic stress disorder symptoms in Vietnam combat veterans. The American Journal of Psychiatry, 152, 936–938.PubMed McNally, R. J., & Shin, L. M. (1995). Association of intelligence with severity of posttraumatic stress disorder symptoms in Vietnam combat veterans. The American Journal of Psychiatry, 152, 936–938.PubMed
go back to reference Milad, M. R., & Rauch, S. L. (2007). The role of the orbitofrontal cortex in anxiety disorders. Annals of the New York Academy of Sciences, 1121, 546–561. doi:10.1196/annals.1401.006. Milad, M. R., & Rauch, S. L. (2007). The role of the orbitofrontal cortex in anxiety disorders. Annals of the New York Academy of Sciences, 1121, 546–561. doi:10.​1196/​annals.​1401.​006.
go back to reference Mirsky, A. F., Anthony, B. J., Duncan, C. C., Ahearn, M. B., & Kellam, S. G. (1991). Analysis of the elements of attention: A neuropsychological approach. Neuropsychology Review, 2, 109–145.PubMedCrossRef Mirsky, A. F., Anthony, B. J., Duncan, C. C., Ahearn, M. B., & Kellam, S. G. (1991). Analysis of the elements of attention: A neuropsychological approach. Neuropsychology Review, 2, 109–145.PubMedCrossRef
go back to reference Morey, R. A., Petty, C. M., Cooper, D. A., LaBar, K. S., & McCarthy, G. (2008). Neural systems for executive and emotional processing are modulated by symptoms of posttraumatic stress disorder in Iraq War Veterans. Psychiatry Research: Neuroimaging, 162(1), 59–72.PubMedCrossRef Morey, R. A., Petty, C. M., Cooper, D. A., LaBar, K. S., & McCarthy, G. (2008). Neural systems for executive and emotional processing are modulated by symptoms of posttraumatic stress disorder in Iraq War Veterans. Psychiatry Research: Neuroimaging, 162(1), 59–72.PubMedCrossRef
go back to reference National Center for Injury Prevention and Control. (2003). Report to Congress on Mild Traumatic Brain Injury in the United States: Steps to Prevent a Serious Public Health Problem. Atlanta, GA: Centers for Disease Control and Prevention. National Center for Injury Prevention and Control. (2003). Report to Congress on Mild Traumatic Brain Injury in the United States: Steps to Prevent a Serious Public Health Problem. Atlanta, GA: Centers for Disease Control and Prevention.
go back to reference Nelson, N. W., Hoelzle, J. B., McGuire, K. A., Gerrier-Auerbach, A. G., Charlesworth, M. J., & Sponheim, S. R. (2010). Evaluation context impacts neuropsychological performance in OEF/OIF Veterans with reported combat-related concussion. Archives of Clinical Neuropsychology, 25, 713–723.PubMedCrossRef Nelson, N. W., Hoelzle, J. B., McGuire, K. A., Gerrier-Auerbach, A. G., Charlesworth, M. J., & Sponheim, S. R. (2010). Evaluation context impacts neuropsychological performance in OEF/OIF Veterans with reported combat-related concussion. Archives of Clinical Neuropsychology, 25, 713–723.PubMedCrossRef
go back to reference Noggle, C. A., Davis, A. S., & Barisa, M. (2008). Neuropsychology and neuroimaging: Integrating and understanding structure and function in clinical practice. In R. C. D’Amato & L. C. Hartlage (Eds.), Essentials of neuropsychological assessment: Treatment planning for rehabilitation (2nd ed., pp. 79–102). New York, NY US: Springer Publishing Co. Noggle, C. A., Davis, A. S., & Barisa, M. (2008). Neuropsychology and neuroimaging: Integrating and understanding structure and function in clinical practice. In R. C. D’Amato & L. C. Hartlage (Eds.), Essentials of neuropsychological assessment: Treatment planning for rehabilitation (2nd ed., pp. 79–102). New York, NY US: Springer Publishing Co.
go back to reference Parslow, R. A., & Jorm, A. F. (2007). Pretrauma and posttrauma neurocognitive functioning and PTSD symptoms in a community sample of young adults. The American Journal of Psychiatry, 164, 509–515.PubMedCrossRef Parslow, R. A., & Jorm, A. F. (2007). Pretrauma and posttrauma neurocognitive functioning and PTSD symptoms in a community sample of young adults. The American Journal of Psychiatry, 164, 509–515.PubMedCrossRef
go back to reference Peskind, E. R., Petrie, E. C., Cross, D. J., Pagulayan, K., McCraw, K., Hoff, D., et al. (2011). Cerebrocerebellar hypometabolism associated with repetitive blast exposure mild traumatic brain injury in 12 Iraq war Veterans with persistent post-concussive symptoms. NeuroImage, 54(1), S76–S82.PubMedCrossRef Peskind, E. R., Petrie, E. C., Cross, D. J., Pagulayan, K., McCraw, K., Hoff, D., et al. (2011). Cerebrocerebellar hypometabolism associated with repetitive blast exposure mild traumatic brain injury in 12 Iraq war Veterans with persistent post-concussive symptoms. NeuroImage, 54(1), S76–S82.PubMedCrossRef
go back to reference Pham, K., Nacher, J., Hof, P. R., & McEwen, B. S. (2003). Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. European Journal of Neuroscience, 17(4), 879–886. Pham, K., Nacher, J., Hof, P. R., & McEwen, B. S. (2003). Repeated restraint stress suppresses neurogenesis and induces biphasic PSA-NCAM expression in the adult rat dentate gyrus. European Journal of Neuroscience, 17(4), 879–886.
go back to reference Rauch, S. L., Shin, L. M., Segal, E., Pitman, R. K., Carson, M. A., McMullin, K., et al. (2003). Selectively reduced regional cortical volumes in post-traumatic stress disorder. Neuroreport, 14, 913–916. Rauch, S. L., Shin, L. M., Segal, E., Pitman, R. K., Carson, M. A., McMullin, K., et al. (2003). Selectively reduced regional cortical volumes in post-traumatic stress disorder. Neuroreport, 14, 913–916.
go back to reference Ricker, J. H., & Arenth, P. M. (2008). Functional neuroimaging in clinical neuropsychology. In J. E. Morgan & J. H. Ricker (Eds.), Textbook of clinical neuropsychology (pp. 840–847). New York, NY US: Psychology Press. Ricker, J. H., & Arenth, P. M. (2008). Functional neuroimaging in clinical neuropsychology. In J. E. Morgan & J. H. Ricker (Eds.), Textbook of clinical neuropsychology (pp. 840–847). New York, NY US: Psychology Press.
go back to reference Rimel, R. W., Giordani, B., Barth, J. T., Boll, T. J., & Jane, J. A. (1981). Disability caused by minor head injury. Neurosurgery, 9, 221–228.PubMedCrossRef Rimel, R. W., Giordani, B., Barth, J. T., Boll, T. J., & Jane, J. A. (1981). Disability caused by minor head injury. Neurosurgery, 9, 221–228.PubMedCrossRef
go back to reference Roozendaal, B., McReynolds, J. R., Van der Zee, E. A., Lee, S., McGaugh, J. L., & McIntyre, C. K. (2009). Glucocorticoid effects on memory consolidation depend on functional interactions between the medial prefrontal cortex and basolateral amygdale. Journal of Neuroscience, 29(45), 14299–14308.PubMedCrossRef Roozendaal, B., McReynolds, J. R., Van der Zee, E. A., Lee, S., McGaugh, J. L., & McIntyre, C. K. (2009). Glucocorticoid effects on memory consolidation depend on functional interactions between the medial prefrontal cortex and basolateral amygdale. Journal of Neuroscience, 29(45), 14299–14308.PubMedCrossRef
go back to reference Roy, M. J., Francis, J., Friedlander, J., Banks-Williams, L., Lande, R. G., Taylor, P., et al. (2010). Improvement in cerebral function with treatment of posttraumatic stress disorder. Annals of the New York Academy of Sciences, 1208, 142–149.PubMedCrossRef Roy, M. J., Francis, J., Friedlander, J., Banks-Williams, L., Lande, R. G., Taylor, P., et al. (2010). Improvement in cerebral function with treatment of posttraumatic stress disorder. Annals of the New York Academy of Sciences, 1208, 142–149.PubMedCrossRef
go back to reference Rubin, D. C., Bernsten, D., & Johansen, M. K. (2008). A memory based model of posttraumatic stress disorder: Evaluating basic assumptions underlying the PTSD diagnosis. Psychological Review, 115, 985–1011.PubMedCrossRef Rubin, D. C., Bernsten, D., & Johansen, M. K. (2008). A memory based model of posttraumatic stress disorder: Evaluating basic assumptions underlying the PTSD diagnosis. Psychological Review, 115, 985–1011.PubMedCrossRef
go back to reference Schmahmann, J. D. (2004). Disorders of the cerebellum: Ataxia, dysmetria of thought, and the cerebellar cognitive affective syndrome. J. Neuropsychiatr. Clin. Neurosci., 16, 367–378.CrossRef Schmahmann, J. D. (2004). Disorders of the cerebellum: Ataxia, dysmetria of thought, and the cerebellar cognitive affective syndrome. J. Neuropsychiatr. Clin. Neurosci., 16, 367–378.CrossRef
go back to reference Schneiderman, A.I., Braver, E.R., & Kang, H.K. (2008). Understanding Sequelae of Injury Mechanisms and Mild Traumatic Brain Injury Incurred during the Conflicts in Iraq and Afghanistan: Persistent Postconcussive Symptoms and Posttraumatic Stress Disorder. Schneiderman, A.I., Braver, E.R., & Kang, H.K. (2008). Understanding Sequelae of Injury Mechanisms and Mild Traumatic Brain Injury Incurred during the Conflicts in Iraq and Afghanistan: Persistent Postconcussive Symptoms and Posttraumatic Stress Disorder.
go back to reference Schretlen, D. J., & Shapiro, A. M. (2003). A quantitative review of the effects of traumatic brain injury on cognitive functioning. International Review of Psychiatry, 15, 545–561.CrossRef Schretlen, D. J., & Shapiro, A. M. (2003). A quantitative review of the effects of traumatic brain injury on cognitive functioning. International Review of Psychiatry, 15, 545–561.CrossRef
go back to reference Schuff, N., Zhang, Y., Zhan, W., Lenoci, M., Ching, C., Boreta, L., et al. (2011). Patterns of altered cortical perfusion and diminished subcortical integrity in posttraumatic stress disorder: An MRI study. NeuroImage, 54(1), S62–S68.PubMedCrossRef Schuff, N., Zhang, Y., Zhan, W., Lenoci, M., Ching, C., Boreta, L., et al. (2011). Patterns of altered cortical perfusion and diminished subcortical integrity in posttraumatic stress disorder: An MRI study. NeuroImage, 54(1), S62–S68.PubMedCrossRef
go back to reference Segev, A., Ramot, A., & Akirav, I. (2012). Stress hormones receptors in the amygdale mediate the effects of stress on the consolidation, but not the retrieval, of a non aversive spatial task. PLoS One, 7(1), e29988.PubMedCrossRef Segev, A., Ramot, A., & Akirav, I. (2012). Stress hormones receptors in the amygdale mediate the effects of stress on the consolidation, but not the retrieval, of a non aversive spatial task. PLoS One, 7(1), e29988.PubMedCrossRef
go back to reference Semple, W.E., Goyer, P.F., McCormick, R., Compton-Toth, B., Morris, E., Donovan, B, … & Schulz, S.C. (1996). Attention and regional cerebral blood flow in posttraumatic stress disorder patients with substance abuse histories. Psychiatry Research: Neuroimaging, 67, 17–28. Semple, W.E., Goyer, P.F., McCormick, R., Compton-Toth, B., Morris, E., Donovan, B, … & Schulz, S.C. (1996). Attention and regional cerebral blood flow in posttraumatic stress disorder patients with substance abuse histories. Psychiatry Research: Neuroimaging, 67, 17–28.
go back to reference Sheppard, S. C., Malatras, J. W., & Israel, A. C. (2010). The impact of deployment on U.S. military families. American Psychologist, 65, 599–609.PubMedCrossRef Sheppard, S. C., Malatras, J. W., & Israel, A. C. (2010). The impact of deployment on U.S. military families. American Psychologist, 65, 599–609.PubMedCrossRef
go back to reference Shin, L. M., Wright, C. I., Cannistraro, P., Wedig, M., McMullin, K., Martis, B., et al. (2005). A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder. Archives of General Psychiatry, 62, 273–281. Shin, L. M., Wright, C. I., Cannistraro, P., Wedig, M., McMullin, K., Martis, B., et al. (2005). A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder. Archives of General Psychiatry, 62, 273–281.
go back to reference Simmons, A. N., & Matthews, S. C. (2011). Neural circuitry of PTSD with or without mild traumatic brain injury: A meta-analysis. Neuropharmacology, In Press, Corrected Proof. Simmons, A. N., & Matthews, S. C. (2011). Neural circuitry of PTSD with or without mild traumatic brain injury: A meta-analysis. Neuropharmacology, In Press, Corrected Proof.
go back to reference Smith, M. E. (2005). Bilateral hippocampal volume reduction in adults with post-traumatic stress disorder: a meta-analysis of structural MRI studies. Hippocampus, 15(6), 798–807. doi:10.1002/hipo.20102. Smith, M. E. (2005). Bilateral hippocampal volume reduction in adults with post-traumatic stress disorder: a meta-analysis of structural MRI studies. Hippocampus, 15(6), 798–807. doi:10.​1002/​hipo.​20102.
go back to reference Spencer, R. J., Drag, L. L., Walker, S. J., & Beiliauskas, L. A. (2010). Self-reported cognitive symptoms following mild traumatic brain injury are poorly associated with neuropsychological performance in OEF/OIF veterans. Journal of Rehabilitation Research and Development, 47(6), 521–530.PubMedCrossRef Spencer, R. J., Drag, L. L., Walker, S. J., & Beiliauskas, L. A. (2010). Self-reported cognitive symptoms following mild traumatic brain injury are poorly associated with neuropsychological performance in OEF/OIF veterans. Journal of Rehabilitation Research and Development, 47(6), 521–530.PubMedCrossRef
go back to reference Sponheim, S. R., McGuire, K. A., Kang, S. S., Davenport, N. D., Aviyente, S., Bernat, E. M., et al. (2011). Evidence of disrupted functional connectivity in the brain after combat-related blast injury. NeuroImage, 54(1), S21–S29.PubMedCrossRef Sponheim, S. R., McGuire, K. A., Kang, S. S., Davenport, N. D., Aviyente, S., Bernat, E. M., et al. (2011). Evidence of disrupted functional connectivity in the brain after combat-related blast injury. NeuroImage, 54(1), S21–S29.PubMedCrossRef
go back to reference Squire, L. R. (1992). Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psych. Rev., 99(2), 195–231.CrossRef Squire, L. R. (1992). Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans. Psych. Rev., 99(2), 195–231.CrossRef
go back to reference Stein, M. B., Koverola, C., Hanna, C., Torchia, M. G., & McClarty, B. (1997). Hippocampal volume in women victimized by childhood sexual abuse. Psychological Medicine, 27(04), 951–959. Stein, M. B., Koverola, C., Hanna, C., Torchia, M. G., & McClarty, B. (1997). Hippocampal volume in women victimized by childhood sexual abuse. Psychological Medicine, 27(04), 951–959.
go back to reference Sullivan, K., Krengel, M., Proctor, S. P., Devine, S., Heeren, T., & White, R. F. (2003). Cognitive functioning in treatment-seeking Gulf War veterans: Pyridostigmine bromide use and PTSD. Journal of Psychopathology and Behavioral Assessment, 25, 95–103.CrossRef Sullivan, K., Krengel, M., Proctor, S. P., Devine, S., Heeren, T., & White, R. F. (2003). Cognitive functioning in treatment-seeking Gulf War veterans: Pyridostigmine bromide use and PTSD. Journal of Psychopathology and Behavioral Assessment, 25, 95–103.CrossRef
go back to reference Tanielian, T., & Jaycox, L. H. (Eds.). (2008). Invisible wounds of war: Psychological and cognitive injuries, their consequences, and services to assist recovery. CA: RAND Corporation. Tanielian, T., & Jaycox, L. H. (Eds.). (2008). Invisible wounds of war: Psychological and cognitive injuries, their consequences, and services to assist recovery. CA: RAND Corporation.
go back to reference Taylor, P. A., & Ford, C. C. (2009). Simulation of blast-induced early time intracranial wave physics leading to traumatic brain injury. Journal of Biomechanical Engineering, 131, 061007.PubMedCrossRef Taylor, P. A., & Ford, C. C. (2009). Simulation of blast-induced early time intracranial wave physics leading to traumatic brain injury. Journal of Biomechanical Engineering, 131, 061007.PubMedCrossRef
go back to reference Terrio, H., Brenner, L. A., Ivins, B. J., Cho, J. M., Helmick, K., Schwab, K., et al. (2009). Traumatic brain injury screening: preliminary findings in a US Army Brigade Combat Team. The Journal of Head Trauma Rehabilitation, 24(1), 14–23.PubMedCrossRef Terrio, H., Brenner, L. A., Ivins, B. J., Cho, J. M., Helmick, K., Schwab, K., et al. (2009). Traumatic brain injury screening: preliminary findings in a US Army Brigade Combat Team. The Journal of Head Trauma Rehabilitation, 24(1), 14–23.PubMedCrossRef
go back to reference Uddo, M., Vasterling, J. J., Brailey, K., & Sutker, P. B. (1993). Memory and attention in combat-related post-traumatic stress disorder (PTSD). Journal of Psychopathology and Behavioral Assessment, 15, 43–52.CrossRef Uddo, M., Vasterling, J. J., Brailey, K., & Sutker, P. B. (1993). Memory and attention in combat-related post-traumatic stress disorder (PTSD). Journal of Psychopathology and Behavioral Assessment, 15, 43–52.CrossRef
go back to reference Van Boven, R. W., Harrington, G. S., Hackney, D. B., Ebel, A., Gauger, G., Bremner, J. D., et al. (2009). Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder. Journal of Rehabilitation Research and Development, 46, 717–756.PubMedCrossRef Van Boven, R. W., Harrington, G. S., Hackney, D. B., Ebel, A., Gauger, G., Bremner, J. D., et al. (2009). Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder. Journal of Rehabilitation Research and Development, 46, 717–756.PubMedCrossRef
go back to reference Vanderploeg, R. D., Belanger, H. G., & Curtiss, G. (2009). Mild traumatic brain injury and posttraumatic stress disorder and their associations with health symptoms. Archives of Physical Medicine and Rehabilitation, 90(7), 1084–1093.PubMedCrossRef Vanderploeg, R. D., Belanger, H. G., & Curtiss, G. (2009). Mild traumatic brain injury and posttraumatic stress disorder and their associations with health symptoms. Archives of Physical Medicine and Rehabilitation, 90(7), 1084–1093.PubMedCrossRef
go back to reference Vasterling, J. J., Brailey, K., Constans, J. I., Borges, A., & Sutker, P. B. (1997). Assessment of intellectual resources in Gulf War veterans: Relationship to PTSD. Assessment, 4, 51–59.CrossRef Vasterling, J. J., Brailey, K., Constans, J. I., Borges, A., & Sutker, P. B. (1997). Assessment of intellectual resources in Gulf War veterans: Relationship to PTSD. Assessment, 4, 51–59.CrossRef
go back to reference Vasterling, J. J., Brailey, K., Constans, J. I., & Sutker, P. B. (1998). Attention and memory dysfunction in posttraumatic stress disorder. Neuropsychology, 12, 125–133.PubMedCrossRef Vasterling, J. J., Brailey, K., Constans, J. I., & Sutker, P. B. (1998). Attention and memory dysfunction in posttraumatic stress disorder. Neuropsychology, 12, 125–133.PubMedCrossRef
go back to reference Vasterling Brailey, K., & Sutker, P. B. (2000). Olfactory identification in combat-related posttraumatic stress disorder. Jounral of Traumatic Stress, 13, 241–253.CrossRef Vasterling Brailey, K., & Sutker, P. B. (2000). Olfactory identification in combat-related posttraumatic stress disorder. Jounral of Traumatic Stress, 13, 241–253.CrossRef
go back to reference Vasterling, J. J., Duke, L. M., Brailey, K., Constans, J. I., Allain, A. N., Jr., & Sutker, P. B. (2002). Attention, learning, and memory performances and intellectual resources in Vietnam veterans: PTSD and no disorder comparisons. Neuropsychology, 16, 5–14.PubMedCrossRef Vasterling, J. J., Duke, L. M., Brailey, K., Constans, J. I., Allain, A. N., Jr., & Sutker, P. B. (2002). Attention, learning, and memory performances and intellectual resources in Vietnam veterans: PTSD and no disorder comparisons. Neuropsychology, 16, 5–14.PubMedCrossRef
go back to reference Vasterling, J. J., & Brailey, K. (2005). Neuropsychological findings in adults with PTSD. In J. J. Vasterling & C. R. Brewin (Eds.), Neuropsychology of PTSD: Biological, cognitive, and clinical perspectives (pp. 178–207). New York: Guilford Press. Vasterling, J. J., & Brailey, K. (2005). Neuropsychological findings in adults with PTSD. In J. J. Vasterling & C. R. Brewin (Eds.), Neuropsychology of PTSD: Biological, cognitive, and clinical perspectives (pp. 178–207). New York: Guilford Press.
go back to reference Vasterling, J. J., Proctor, S. P., Amoroso, P., Kane, R., Heeren, T., & White, R. F. (2006). Neuropsychological Outcomes of Army Personnel Following Deployment to the Iraq War. JAMA: The Journal of the American Medical Association, 296(5), 519–529.CrossRef Vasterling, J. J., Proctor, S. P., Amoroso, P., Kane, R., Heeren, T., & White, R. F. (2006). Neuropsychological Outcomes of Army Personnel Following Deployment to the Iraq War. JAMA: The Journal of the American Medical Association, 296(5), 519–529.CrossRef
go back to reference Vasterling, J. J., & Verfaellie, M. (2009). Posttraumatic stress disorder: A neurocognitive perspective. Journal of the International Neuropsychological Society, 15, 826–829.PubMedCrossRef Vasterling, J. J., & Verfaellie, M. (2009). Posttraumatic stress disorder: A neurocognitive perspective. Journal of the International Neuropsychological Society, 15, 826–829.PubMedCrossRef
go back to reference Vasterling, J. J., Verfaellie, M., & Sullivan, K. D. (2009). Mild traumatic brain injury and posttraumatic stress disorder in returning veterans: Perspectives from cognitive neuroscience. Clinical Psychology Review, 29, 674–684.PubMedCrossRef Vasterling, J. J., Verfaellie, M., & Sullivan, K. D. (2009). Mild traumatic brain injury and posttraumatic stress disorder in returning veterans: Perspectives from cognitive neuroscience. Clinical Psychology Review, 29, 674–684.PubMedCrossRef
go back to reference Vythilingam, M., Nelson, E. E., Scaramozza, M., Waldeck, T., Hazlett, G., Southwick, S. M., et al. (2009). Reward circuitry in resilience to severe trauma: An fMRI investigation of resilient special forces soldiers. Psychiatry Research: Neuroimaging, 172(1), 75–77.PubMedCrossRef Vythilingam, M., Nelson, E. E., Scaramozza, M., Waldeck, T., Hazlett, G., Southwick, S. M., et al. (2009). Reward circuitry in resilience to severe trauma: An fMRI investigation of resilient special forces soldiers. Psychiatry Research: Neuroimaging, 172(1), 75–77.PubMedCrossRef
go back to reference Whitney, K. A., Shepard, P. H., Williams, A. L., Davis, J. J., & Adams, K. M. (2009). The Medical Symptom Validity Test in the evaluation of Operation Iraqi Freedom/Enduring Freedom soldiers: A preliminary study. Archives of Clinical Neuropsychology, 24, 145–152.PubMedCrossRef Whitney, K. A., Shepard, P. H., Williams, A. L., Davis, J. J., & Adams, K. M. (2009). The Medical Symptom Validity Test in the evaluation of Operation Iraqi Freedom/Enduring Freedom soldiers: A preliminary study. Archives of Clinical Neuropsychology, 24, 145–152.PubMedCrossRef
go back to reference Williams, L. M., Liddell, B. J., Kemp, A. H., Bryant, R. A., Meares, R. A., Peduto, A. S., & Gordon, E. (2006). Amygdala-prefrontal dissociation of subliminal and supraliminal fear. Human Brain Mapping, 27(8), 652–661.PubMedCrossRef Williams, L. M., Liddell, B. J., Kemp, A. H., Bryant, R. A., Meares, R. A., Peduto, A. S., & Gordon, E. (2006). Amygdala-prefrontal dissociation of subliminal and supraliminal fear. Human Brain Mapping, 27(8), 652–661.PubMedCrossRef
go back to reference Woodward, S. H., Kaloupek, D. G., Streeter, C. C., Kimble, M. O., Reiss, A. L., Eliez, S., et al. (2006a). Hippocampal volume, PTSD, and alcoholism in combat veterans. American Journal of Psychiatry, 163(4), 674–681. Woodward, S. H., Kaloupek, D. G., Streeter, C. C., Kimble, M. O., Reiss, A. L., Eliez, S., et al. (2006a). Hippocampal volume, PTSD, and alcoholism in combat veterans. American Journal of Psychiatry, 163(4), 674–681.
go back to reference Woodward, S. H., Kaloupek, D. G., Streeter, C. C., Martinez, C., Schaer, M., & Eliez, S. (2006b). Decreased anterior congulate volume in combat-related PTSD. Biological Psychiatry, 59, 582–587.PubMedCrossRef Woodward, S. H., Kaloupek, D. G., Streeter, C. C., Martinez, C., Schaer, M., & Eliez, S. (2006b). Decreased anterior congulate volume in combat-related PTSD. Biological Psychiatry, 59, 582–587.PubMedCrossRef
go back to reference Woodward, S. H., Schaer, M., Kaloupek, D. G., Cediel, L., & Eliez, S. (2009). Smaller global and regional cortical volume in combat-related posttraumatic stress disorder. Archives of General Psychiatry, 66(12), 1373–1382. doi:10.1001/archgenpsychiatry.2009.160. Woodward, S. H., Schaer, M., Kaloupek, D. G., Cediel, L., & Eliez, S. (2009). Smaller global and regional cortical volume in combat-related posttraumatic stress disorder. Archives of General Psychiatry, 66(12), 1373–1382. doi:10.​1001/​archgenpsychiatr​y.​2009.​160.
go back to reference Yamasue, H., Kasai, K., Iwanami, A., Ohtani, T., Yamada, H., Abe, O., et al. (2003). Voxel-based analysis of MRI reveals anterior cingulate gray-matter volume reduction in posttraumatic stress disorder due to terrorism. Proceedings of the National Academy of Sciences of the United States of America, 100, 9039–9043. Yamasue, H., Kasai, K., Iwanami, A., Ohtani, T., Yamada, H., Abe, O., et al. (2003). Voxel-based analysis of MRI reveals anterior cingulate gray-matter volume reduction in posttraumatic stress disorder due to terrorism. Proceedings of the National Academy of Sciences of the United States of America, 100, 9039–9043.
Metadata
Title
Neuropsychological Sequelae of PTSD and TBI Following War Deployment among OEF/OIF Veterans
Authors
Sara Dolan
Sarah Martindale
Jennifer Robinson
Nathan A. Kimbrel
Eric C. Meyer
Marc I. Kruse
Sandra B. Morissette
Keith A. Young
Suzy Bird Gulliver
Publication date
01-03-2012
Publisher
Springer US
Published in
Neuropsychology Review / Issue 1/2012
Print ISSN: 1040-7308
Electronic ISSN: 1573-6660
DOI
https://doi.org/10.1007/s11065-012-9190-5

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