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Neuropsychology Review
Published in: Neuropsychology Review 2/2010

01-06-2010 | Review

MR Diffusion Tensor Imaging: A Window into White Matter Integrity of the Working Brain

Authors: Sandra Chanraud, Natalie Zahr, Edith V. Sullivan, Adolf Pfefferbaum

Published in: Neuropsychology Review | Issue 2/2010

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Abstract

As Norman Geschwind asserted in 1965, syndromes resulting from white matter lesions could produce deficits in higher-order functions and “disconnexion” or the interruption of connection between gray matter regions could be as disruptive as trauma to those regions per se. The advent of in vivo diffusion tensor imaging, which allows quantitative characterization of white matter fiber integrity in health and disease, has served to strengthen Geschwind’s proposal. Here we present an overview of the principles of diffusion tensor imaging (DTI) and its contribution to progress in our current understanding of normal and pathological brain function.
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Metadata
Title
MR Diffusion Tensor Imaging: A Window into White Matter Integrity of the Working Brain
Authors
Sandra Chanraud
Natalie Zahr
Edith V. Sullivan
Adolf Pfefferbaum
Publication date
01-06-2010
Publisher
Springer US
Published in
Neuropsychology Review / Issue 2/2010
Print ISSN: 1040-7308
Electronic ISSN: 1573-6660
DOI
https://doi.org/10.1007/s11065-010-9129-7

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