Published in:
01-09-2010 | Case Report
Multiple paraneoplastic diseases occurring in the same patient after thymomectomy
Authors:
C. Briani, A. Cagnin, S. Blandamura, G. Altavilla
Published in:
Journal of Neuro-Oncology
|
Issue 2/2010
Login to get access
Abstract
Thymoma-associated paraneoplastic diseases include myasthenia gravis (MG), neuromyotonia (NMT), Morvan’s syndrome, and several non-neurological paraneoplastic manifestations, including glomerulonephritis. Paraneoplastic syndromes often precede the occurrence of thymoma, but cases occurring after thymomectomy, which sometimes herald the recurrence of thymoma, have also been described. We report on a patient who developed MG after thymomectomy for a malignant thymoma. After MG remission, NMT and Morvan’s syndrome occurred, which heralded a mediastinic recurrence, as demonstrated only by autopsy findings.