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Published in: Journal of Neuro-Oncology 1/2009

01-01-2009 | Clinical study - patient study

Long-lasting successful cerebral response with sorafenib in advanced renal cell carcinoma

Authors: Francesca Valcamonico, Vittorio Ferrari, Vito Amoroso, Giovanni Rangoni, Edda Simoncini, Patrizia Marpicati, Lucia Vassalli, Salvatore Grisanti, Giovanni Marini

Published in: Journal of Neuro-Oncology | Issue 1/2009

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Abstract

We report the case of a 75-year old woman who received sorafenib (Nexavar®, Bayer Pharmaceuticals Corporation, West Haven, CT) for a CNS relapse of clear cell renal cell carcinoma. After four months of sorafenib treatment, a brain magnetic resonance imaging showed 95%-volumetric regression of cerebral metastasis. To the best of our knowledge, this is the first almost complete resolution of brain metastases in renal cell carcinoma treated with sorafenib that has been described.
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Metadata
Title
Long-lasting successful cerebral response with sorafenib in advanced renal cell carcinoma
Authors
Francesca Valcamonico
Vittorio Ferrari
Vito Amoroso
Giovanni Rangoni
Edda Simoncini
Patrizia Marpicati
Lucia Vassalli
Salvatore Grisanti
Giovanni Marini
Publication date
01-01-2009
Publisher
Springer US
Published in
Journal of Neuro-Oncology / Issue 1/2009
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI
https://doi.org/10.1007/s11060-008-9676-4

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