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Journal of Mammary Gland Biology and Neoplasia
Published in: Journal of Mammary Gland Biology and Neoplasia 2/2019

01-06-2019

A Comparative Review of Mixed Mammary Tumors in Mammals

Authors: Eman S. A. Saad, Jacqueline S. Y. Lam, Awf A. Al-Khan, Mourad Tayebi, Michael J. Day, Samantha J. Richardson, Janine A. Danks

Published in: Journal of Mammary Gland Biology and Neoplasia | Issue 2/2019

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Abstract

Mixed tumors are characterized by the histological identification of two or more cell types. Commonly, a mixture of epithelial and myoepithelial cells is included in abundant stroma, which can consist of myxoid, chondroid or bony matrices. Spontaneously arising mixed tumors are rare lesions in the human breast but are common in human salivary glands and canine mammary glands. Subtle histopathological characteristics and overlapping attributes of malignant lesions with other benign lesions can lead to a diagnostic challenge. Mixed tumors can present as benign or malignant. While malignant mixed tumors are quite rare in the human breast they have a poor prognosis. Benign mixed mammary tumors occur more frequently in female dogs than in humans and are usually associated with a good prognosis. This review will provide a comprehensive overview of mixed mammary tumors, across various mammalian species.
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Metadata
Title
A Comparative Review of Mixed Mammary Tumors in Mammals
Authors
Eman S. A. Saad
Jacqueline S. Y. Lam
Awf A. Al-Khan
Mourad Tayebi
Michael J. Day
Samantha J. Richardson
Janine A. Danks
Publication date
01-06-2019
Publisher
Springer US
Published in
Journal of Mammary Gland Biology and Neoplasia / Issue 2/2019
Print ISSN: 1083-3021
Electronic ISSN: 1573-7039
DOI
https://doi.org/10.1007/s10911-018-9422-2

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