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Journal of Mammary Gland Biology and Neoplasia
Published in: Journal of Mammary Gland Biology and Neoplasia 3-4/2006

01-10-2006

Mammary Gland Macrophages: Pleiotropic Functions in Mammary Development

Authors: Kathryn L. Schwertfeger, Jeffrey M. Rosen, Donald A. Cohen

Published in: Journal of Mammary Gland Biology and Neoplasia | Issue 3-4/2006

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Abstract

Mammary gland development is a complex process involving epithelial cells and supporting stromal cells. Macrophages (M∅s) are an important component of the mammary gland stroma and are critical for normal mammary gland development; however, the mechanisms by which macrophages regulate these processes are not well understood. M∅s are known to interact with numerous cell types, including epithelial cells, fibroblasts, adipocytes, and endothelial cells, all of which are significant components of mammary gland development. Therefore, the purpose of this review is to describe the interactions between M∅s and these various cell types and use this knowledge to identify potential functions of M∅s in the mammary gland.
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Metadata
Title
Mammary Gland Macrophages: Pleiotropic Functions in Mammary Development
Authors
Kathryn L. Schwertfeger
Jeffrey M. Rosen
Donald A. Cohen
Publication date
01-10-2006
Published in
Journal of Mammary Gland Biology and Neoplasia / Issue 3-4/2006
Print ISSN: 1083-3021
Electronic ISSN: 1573-7039
DOI
https://doi.org/10.1007/s10911-006-9028-y

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