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Published in: Journal of Immigrant and Minority Health 2/2018

01-04-2018 | Original Paper

Seroprevalence of Histoplasmosis in Somali, Burmese, and Hmong Refugees Residing in Thailand and Kenya

Authors: Nathan C. Bahr, Deborah Lee, William M. Stauffer, Michelle Durkin, Martin S. Cetron, L. Joseph Wheat, David R. Boulware

Published in: Journal of Immigrant and Minority Health | Issue 2/2018

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Abstract

Histoplasmosis is known to be endemic to the Midwestern United States, but cases have been reported throughout much of the world. Somali, Hmong, and Burmese (ethnically Karen) persons make up some of the largest refugee populations coming the United States in recent years. Yet, information about risk of Histoplasma capsulatum infection amongst these populations is limited. This study used the CDC Migrant Serum Bank to test ~100 samples from each of Somali, Burmese, and Hmong U.S.-bound refugees. Samples were tested by enzyme immunoassay for Histoplasma capsulatum IgG. Overall 1% (2/299) of refugee serum samples were positive for H. capsulatum IgG. One of 99 samples obtained from Hmong refugees was positive, and the other positive sample came from among 100 Burmese refugee samples. H capsulatum IgG positivity was detected at low levels in Hmong and Burmese refugees. No IgG positivity was detected among 100 Somali refugees.
Literature
1.
go back to reference Wheat LJ, Azar MM, Bahr NC, Spec A, Relich RF, Hage C. Histoplasmosis. Infect Dis Clin North Am. 2016;30(1):207–27.CrossRefPubMed Wheat LJ, Azar MM, Bahr NC, Spec A, Relich RF, Hage C. Histoplasmosis. Infect Dis Clin North Am. 2016;30(1):207–27.CrossRefPubMed
2.
3.
go back to reference Christie A. Histoplasmosis and pulmonary calcification—geographic distribution. Am J Trop Med Hyg. 1951;31(6):742–52.CrossRefPubMed Christie A. Histoplasmosis and pulmonary calcification—geographic distribution. Am J Trop Med Hyg. 1951;31(6):742–52.CrossRefPubMed
4.
go back to reference Edwards LB, Acquaviva FA, Livesay VT, Cross FW, Palmer CE. An atlas of sensitivity to tuberculin, PPD-B, and histoplasmin in the United States. Am Rev Respir Dis. 1969;99(4):Suppl:1–132. Edwards LB, Acquaviva FA, Livesay VT, Cross FW, Palmer CE. An atlas of sensitivity to tuberculin, PPD-B, and histoplasmin in the United States. Am Rev Respir Dis. 1969;99(4):Suppl:1–132.
5.
go back to reference Bahr NC, Antinori S, Wheat LJ, Sarosi GA. Histoplasmosis infections worldwide: thinking outside of the Ohio River valley. Curr Trop Med Rep. 2015;2(2):70–80.CrossRefPubMedPubMedCentral Bahr NC, Antinori S, Wheat LJ, Sarosi GA. Histoplasmosis infections worldwide: thinking outside of the Ohio River valley. Curr Trop Med Rep. 2015;2(2):70–80.CrossRefPubMedPubMedCentral
6.
go back to reference Wheat LJ, Freifeld AG, Kleiman MB, Baddley JW, McKinsey DS, Loyd JE, et al. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect. 2007;45(7):807–25.CrossRef Wheat LJ, Freifeld AG, Kleiman MB, Baddley JW, McKinsey DS, Loyd JE, et al. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect. 2007;45(7):807–25.CrossRef
7.
go back to reference Hage CA, Azar MM, Bahr N, Loyd J, Wheat LJ. Histoplasmosis: up-to-date evidence-based approach to diagnosis and management. Semin Respir Crit Care Med. 2015;36(5):729–45.CrossRefPubMed Hage CA, Azar MM, Bahr N, Loyd J, Wheat LJ. Histoplasmosis: up-to-date evidence-based approach to diagnosis and management. Semin Respir Crit Care Med. 2015;36(5):729–45.CrossRefPubMed
8.
go back to reference Neglected Histoplasmosis in Latin America Group. Disseminated histoplasmosis in Central and South America, the invisible elephant: the lethal blind spot of international health organizations. AIDS. 2016;30(2):167–70.CrossRef Neglected Histoplasmosis in Latin America Group. Disseminated histoplasmosis in Central and South America, the invisible elephant: the lethal blind spot of international health organizations. AIDS. 2016;30(2):167–70.CrossRef
12.
go back to reference Lee D. Personal communication to authors. 2016. Lee D. Personal communication to authors. 2016.
14.
go back to reference Hung MN, Sun HY, Hsueh PR, Hung CC, Chang SC. Meningitis due to Histoplasma capsulatum and Mycobacterium tuberculosis in a returned traveler with acquired immunodeficiency syndrome. J Formos Med Assoc. 2005;104(11):860–3.PubMed Hung MN, Sun HY, Hsueh PR, Hung CC, Chang SC. Meningitis due to Histoplasma capsulatum and Mycobacterium tuberculosis in a returned traveler with acquired immunodeficiency syndrome. J Formos Med Assoc. 2005;104(11):860–3.PubMed
15.
go back to reference Jayanetra P, Prajaktam R, Satapathayawong B, Atichartrakarn V, Thianprasit M, Waropastrakul C, Poopaibul K, Kanjanasthiti P. The magnitude of the public health problem posed by the mycoses. Part II: the lack of information. J Infect Dis Antimicrob Agents. 1987;4:175–84. Jayanetra P, Prajaktam R, Satapathayawong B, Atichartrakarn V, Thianprasit M, Waropastrakul C, Poopaibul K, Kanjanasthiti P. The magnitude of the public health problem posed by the mycoses. Part II: the lack of information. J Infect Dis Antimicrob Agents. 1987;4:175–84.
16.
go back to reference Jordan AS, Chavada R, Nagendra V, McNeil HP, Kociuba K, Gibson KA. A budding surprise from the joint. Med J Aust. 2013;199(10):700–1.CrossRefPubMed Jordan AS, Chavada R, Nagendra V, McNeil HP, Kociuba K, Gibson KA. A budding surprise from the joint. Med J Aust. 2013;199(10):700–1.CrossRefPubMed
17.
go back to reference Maresca B, Ali AI, Kobayashi GS, Sacco M. Incidence of histoplasmin skin test reactivity in Somalia: an epidemiological study. Mycopathologia. 1987;98(2):77–81.CrossRefPubMed Maresca B, Ali AI, Kobayashi GS, Sacco M. Incidence of histoplasmin skin test reactivity in Somalia: an epidemiological study. Mycopathologia. 1987;98(2):77–81.CrossRefPubMed
18.
go back to reference Nuti M, Tarabini GC, Adorisio E, Zardi O. Histoplasmosis diffusion in Somalia: study of skin-test and serological survey. Biochem Exp Biol. 1979;15(2):111–7.PubMed Nuti M, Tarabini GC, Adorisio E, Zardi O. Histoplasmosis diffusion in Somalia: study of skin-test and serological survey. Biochem Exp Biol. 1979;15(2):111–7.PubMed
19.
go back to reference Pamnani R, Rajab JA, Githang’a J, Kasmani R. Disseminated histoplasmosis diagnosed on bone marrow aspirate cytology: report of four cases. East Afr Med J. 2009;86(12 Suppl):S102–5.PubMed Pamnani R, Rajab JA, Githang’a J, Kasmani R. Disseminated histoplasmosis diagnosed on bone marrow aspirate cytology: report of four cases. East Afr Med J. 2009;86(12 Suppl):S102–5.PubMed
20.
go back to reference Randhawa HS. Occurrence of histoplasmosis in Asia. Mycopathologia et mycologia applicata. 1970;41(1):75–89.CrossRefPubMed Randhawa HS. Occurrence of histoplasmosis in Asia. Mycopathologia et mycologia applicata. 1970;41(1):75–89.CrossRefPubMed
21.
go back to reference Posey DL, Blackburn BG, Weinberg M, Flagg EW, Ortega L, Wilson M, et al. High prevalence and presumptive treatment of schistosomiasis and strongyloidiasis among African refugees. Clin Infect Dis. 2007;45(10):1310–5.CrossRefPubMed Posey DL, Blackburn BG, Weinberg M, Flagg EW, Ortega L, Wilson M, et al. High prevalence and presumptive treatment of schistosomiasis and strongyloidiasis among African refugees. Clin Infect Dis. 2007;45(10):1310–5.CrossRefPubMed
22.
go back to reference Bahr NC, Sarosi GA, Meya DB, Bohjanen PR, Richer SM, Swartzentruber S, et al. Seroprevalence of histoplasmosis in Kampala, Uganda. Med Mycol. 2016;54(3):295–300.CrossRefPubMed Bahr NC, Sarosi GA, Meya DB, Bohjanen PR, Richer SM, Swartzentruber S, et al. Seroprevalence of histoplasmosis in Kampala, Uganda. Med Mycol. 2016;54(3):295–300.CrossRefPubMed
23.
go back to reference Richer SM, Smedema ML, Durkin MM, Herman KM, Hage CA, Fuller D, et al. Improved diagnosis of acute pulmonary histoplasmosis by combining antigen and antibody detection. Clin Infect Dis. 2016;62(7):896–902.CrossRefPubMedPubMedCentral Richer SM, Smedema ML, Durkin MM, Herman KM, Hage CA, Fuller D, et al. Improved diagnosis of acute pulmonary histoplasmosis by combining antigen and antibody detection. Clin Infect Dis. 2016;62(7):896–902.CrossRefPubMedPubMedCentral
24.
go back to reference Norkaew T, Ohno H, Sriburee P, Tanabe K, Tharavichitkul P, Takarn P, et al. Detection of environmental sources of Histoplasma capsulatum in Chiang Mai, Thailand, by nested PCR. Mycopathologia. 2013;176(5–6):395–402.CrossRefPubMed Norkaew T, Ohno H, Sriburee P, Tanabe K, Tharavichitkul P, Takarn P, et al. Detection of environmental sources of Histoplasma capsulatum in Chiang Mai, Thailand, by nested PCR. Mycopathologia. 2013;176(5–6):395–402.CrossRefPubMed
25.
go back to reference Wongprommek P, Chayakulkeeree M. Clinical characteristics of histoplasmosis in Siriraj hospital. J Med Assoc Thai. 2016;99(3):257–61.PubMed Wongprommek P, Chayakulkeeree M. Clinical characteristics of histoplasmosis in Siriraj hospital. J Med Assoc Thai. 2016;99(3):257–61.PubMed
26.
go back to reference Wheat J, French ML, Kohler RB, Zimmerman SE, Smith WR, Norton JA, et al. The diagnostic laboratory tests for histoplasmosis: analysis of experience in a large urban outbreak. Ann Intern Med. 1982;97(5):680–5.CrossRefPubMed Wheat J, French ML, Kohler RB, Zimmerman SE, Smith WR, Norton JA, et al. The diagnostic laboratory tests for histoplasmosis: analysis of experience in a large urban outbreak. Ann Intern Med. 1982;97(5):680–5.CrossRefPubMed
27.
go back to reference Wheat J, Wheat H, Connolly P, Kleiman M, Supparatpinyo K, Nelson K, et al. Cross-reactivity in Histoplasma capsulatum variety capsulatum antigen assays of urine samples from patients with endemic mycoses. Clin Infect Dis. 1997;24(6):1169–71.CrossRefPubMed Wheat J, Wheat H, Connolly P, Kleiman M, Supparatpinyo K, Nelson K, et al. Cross-reactivity in Histoplasma capsulatum variety capsulatum antigen assays of urine samples from patients with endemic mycoses. Clin Infect Dis. 1997;24(6):1169–71.CrossRefPubMed
28.
go back to reference Mochi A, Edwards PQ. Geographical distribution of histoplasmosis and histoplasmin sensitivity. Bull World Health Organ. 1952;5(3):259–91.PubMedPubMedCentral Mochi A, Edwards PQ. Geographical distribution of histoplasmosis and histoplasmin sensitivity. Bull World Health Organ. 1952;5(3):259–91.PubMedPubMedCentral
Metadata
Title
Seroprevalence of Histoplasmosis in Somali, Burmese, and Hmong Refugees Residing in Thailand and Kenya
Authors
Nathan C. Bahr
Deborah Lee
William M. Stauffer
Michelle Durkin
Martin S. Cetron
L. Joseph Wheat
David R. Boulware
Publication date
01-04-2018
Publisher
Springer US
Published in
Journal of Immigrant and Minority Health / Issue 2/2018
Print ISSN: 1557-1912
Electronic ISSN: 1557-1920
DOI
https://doi.org/10.1007/s10903-017-0595-3

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