Skip to main content
Top
Published in: Journal of Immigrant and Minority Health 4/2010

Open Access 01-08-2010 | Original Paper

Multi-Level Barriers to LTBI Treatment: A Research Note

Authors: Linda Hill, Elaine Blumberg, Carol Sipan, Katharine Schmitz, Joshua West, Norma Kelley, Melbourne Hovell

Published in: Journal of Immigrant and Minority Health | Issue 4/2010

Login to get access

Abstract

Background This study describes the barriers to effective and timely LTBI treatment encountered in a research study on INH adherence in Latino adolescents. Method Participant study logs were reviewed, results of continuing medical education pretests for medical providers were examined, and participating medical facilities were contacted in order to construct a profile of multi-level barriers to LTBI treatment. Results A total of 285 TST positive Latino (96%) high school students were recruited into the trial. We encountered a lack of understanding of the gravity of tuberculosis infection among both the public and providers of health care. Parents and adolescents cited competing priorities, transportation problems and financial constraints as reasons for non-compliance. Discussion Improved education of the public and physicians is needed regarding the gravity of the disease and the value of treatment, as well as public and financial support for LTBI treatment by both the government and the medical community.
Literature
2.
go back to reference World Health Organization. Strategic framework to decrease the burden of TB/HIV. Geneva, World Health Organization, 2002; WHO/CDS/TB/2002.296, WHO/HIV_AIDS/2002.2. World Health Organization. Strategic framework to decrease the burden of TB/HIV. Geneva, World Health Organization, 2002; WHO/CDS/TB/2002.296, WHO/HIV_AIDS/2002.2.
4.
go back to reference Vynnychy E, Fine PE. The natural history of tuberculosis: the implications of age-dependent risks of disease and the role of reinfection. Epidemiol Infect. 1997;119:183–201.CrossRef Vynnychy E, Fine PE. The natural history of tuberculosis: the implications of age-dependent risks of disease and the role of reinfection. Epidemiol Infect. 1997;119:183–201.CrossRef
5.
go back to reference Selwyn PA, Hartel D, et al. A prospective study of the risk of tuberculosis among intravenous drug users with human immunodeficiency virus infection. N Engl J Med. 1989;320:545–50.PubMed Selwyn PA, Hartel D, et al. A prospective study of the risk of tuberculosis among intravenous drug users with human immunodeficiency virus infection. N Engl J Med. 1989;320:545–50.PubMed
6.
go back to reference Centers for Disease Control and Prevention. Reported tuberculosis in the US. Atlanta, GA: US DHHS, CDC; Sept 2006. Centers for Disease Control and Prevention. Reported tuberculosis in the US. Atlanta, GA: US DHHS, CDC; Sept 2006.
7.
go back to reference Centers for Disease Control and Prevention. Tuberculosis elimination revisited: obstacles, opportunities, and a renewed commitment—advisory council for the elimination of tuberculosis (ACET). MMWR. 1999;48(RR09):1–13. Centers for Disease Control and Prevention. Tuberculosis elimination revisited: obstacles, opportunities, and a renewed commitment—advisory council for the elimination of tuberculosis (ACET). MMWR. 1999;48(RR09):1–13.
8.
go back to reference Pediatric Tuberculosis Collaborative Group. Targeted tuberculin skin testing and treatment of latent tuberculosis infection in children and adolescents. Pediatrics. 2004;114(4):1175–201.CrossRef Pediatric Tuberculosis Collaborative Group. Targeted tuberculin skin testing and treatment of latent tuberculosis infection in children and adolescents. Pediatrics. 2004;114(4):1175–201.CrossRef
9.
go back to reference Morisky D, Ebin V, et al. Assessment of tuberculosis treatment completion in an ethnically diverse population using two data sources. Eval Health Prof. 2003;26(1):43–58.CrossRefPubMed Morisky D, Ebin V, et al. Assessment of tuberculosis treatment completion in an ethnically diverse population using two data sources. Eval Health Prof. 2003;26(1):43–58.CrossRefPubMed
10.
go back to reference Addington WW. Patient compliance: the most serious remaining problem in the control of tuberculosis in the United States. Chest. 1979;76:741–3.PubMed Addington WW. Patient compliance: the most serious remaining problem in the control of tuberculosis in the United States. Chest. 1979;76:741–3.PubMed
11.
go back to reference Fox W. Compliance of patients and physicians: experience and lessons from tuberculosis-I. BMJ. 1983;287:33–5.CrossRefPubMed Fox W. Compliance of patients and physicians: experience and lessons from tuberculosis-I. BMJ. 1983;287:33–5.CrossRefPubMed
12.
go back to reference Sumartojo E. When tuberculosis treatment fails: a social behavioral account of patient adherence. Am Rev Respir Dis. 1993;147:1311–20.PubMed Sumartojo E. When tuberculosis treatment fails: a social behavioral account of patient adherence. Am Rev Respir Dis. 1993;147:1311–20.PubMed
13.
14.
go back to reference Centers for Disease Control and Prevention. Approaches to improving adherence to antituberculosis therapy. MMWR 1993;42:74–5, 81. Centers for Disease Control and Prevention. Approaches to improving adherence to antituberculosis therapy. MMWR 1993;42:74–5, 81.
15.
go back to reference Sbarbaro JA, Sbarbaro JB. Compliance and supervision of chemotherapy of tuberculosis. Sem Respir Infect. 1994;9:120–7. Sbarbaro JA, Sbarbaro JB. Compliance and supervision of chemotherapy of tuberculosis. Sem Respir Infect. 1994;9:120–7.
16.
go back to reference Volmink J, Garner P. Strategies for promoting completion of treatment in patients with tuberculosis. In: Garner P, Gelband H, Olliaro P, Salinas R, Volmink J, Wilkinson D, editors. Infectious diseases module of the Cochrane database of systematic reviews [updated 15 April 1997]. Oxford: Update Software; 1997 (available in the Cochrane Library). Volmink J, Garner P. Strategies for promoting completion of treatment in patients with tuberculosis. In: Garner P, Gelband H, Olliaro P, Salinas R, Volmink J, Wilkinson D, editors. Infectious diseases module of the Cochrane database of systematic reviews [updated 15 April 1997]. Oxford: Update Software; 1997 (available in the Cochrane Library).
17.
go back to reference Starr M, Sawyer S, et al. A novel approach to monitoring adherence to preventive therapy for tuberculosis in adolescence. J Pediatr Child Health. 1999;35(4):350–4.CrossRef Starr M, Sawyer S, et al. A novel approach to monitoring adherence to preventive therapy for tuberculosis in adolescence. J Pediatr Child Health. 1999;35(4):350–4.CrossRef
18.
go back to reference Barry MA, Shirley L, et al. Tuberculosis infection in urban adolescents: results of a school based testing program. AJPH. 1990;80:439–41.CrossRef Barry MA, Shirley L, et al. Tuberculosis infection in urban adolescents: results of a school based testing program. AJPH. 1990;80:439–41.CrossRef
19.
go back to reference Hovell MF, Sipan CL, Blumberg EJ, Hofstetter CR, Slymen D, Friedman L, Moser K, Kelley NJ, Vera AY. Increasing Latino adolescents’ adherence to treatment for latent Tuberculosis infection: a controlled trial. AJPH. 2003;93:1871–7.CrossRef Hovell MF, Sipan CL, Blumberg EJ, Hofstetter CR, Slymen D, Friedman L, Moser K, Kelley NJ, Vera AY. Increasing Latino adolescents’ adherence to treatment for latent Tuberculosis infection: a controlled trial. AJPH. 2003;93:1871–7.CrossRef
21.
go back to reference Centers for Disease Control, Prevention, Guide for Primary Care Providers. Targeted tuberculin testing, treatment of latent tuberculosis infection. Atlanta, GA: DHHS, CDC, National Center for HIV, STD, and TB Prevention, Division of Tuberculosis Elimination; 2005. Centers for Disease Control, Prevention, Guide for Primary Care Providers. Targeted tuberculin testing, treatment of latent tuberculosis infection. Atlanta, GA: DHHS, CDC, National Center for HIV, STD, and TB Prevention, Division of Tuberculosis Elimination; 2005.
22.
go back to reference Kerner JF, Breen N, Tefft MC, Silsby J, Marın G, Gamba RJ. A new measure of acculturation for hispanics: The bidimensional scale for hispanics (BAS). Hisp J Behav Sci. 1996;18(3):297–316.CrossRef Kerner JF, Breen N, Tefft MC, Silsby J, Marın G, Gamba RJ. A new measure of acculturation for hispanics: The bidimensional scale for hispanics (BAS). Hisp J Behav Sci. 1996;18(3):297–316.CrossRef
23.
go back to reference Centers for Disease Control and Prevention. The use of preventive therapy for tuberculosis infection in the United States: recommendations of the Advisory Committee for Elimination of Tuberculosis. MMWR. 1995;30(RR-8):9–12. Centers for Disease Control and Prevention. The use of preventive therapy for tuberculosis infection in the United States: recommendations of the Advisory Committee for Elimination of Tuberculosis. MMWR. 1995;30(RR-8):9–12.
24.
go back to reference Ozuah PO, Ozuah TP, Stein RE, Burton W, Mulvihill M. Evaluation of a risk assessment questionnaire used to target tuberculin skin testing in children. JAMA. 2001;285(4):451–3.CrossRefPubMed Ozuah PO, Ozuah TP, Stein RE, Burton W, Mulvihill M. Evaluation of a risk assessment questionnaire used to target tuberculin skin testing in children. JAMA. 2001;285(4):451–3.CrossRefPubMed
25.
go back to reference Shieh FK, Snyder G, Horsburgh CR, Bernardo J, Murphy C, Saukkonen JJ. Predicting non-completion of treatment for latent tuberculosis infection: a prospective survey. Am J Respir Crit Care Med. 2006;174(6):717–21.CrossRefPubMed Shieh FK, Snyder G, Horsburgh CR, Bernardo J, Murphy C, Saukkonen JJ. Predicting non-completion of treatment for latent tuberculosis infection: a prospective survey. Am J Respir Crit Care Med. 2006;174(6):717–21.CrossRefPubMed
26.
go back to reference Jackson M, Harrity S, Hoffman H, Catanzaro A. A survey of health professions students for knowledge, attitudes, and confidence about tuberculosis, 2005. BMC Publ Health. 2007;7(147):219.CrossRef Jackson M, Harrity S, Hoffman H, Catanzaro A. A survey of health professions students for knowledge, attitudes, and confidence about tuberculosis, 2005. BMC Publ Health. 2007;7(147):219.CrossRef
27.
go back to reference Salazar-Schicchi J, Jedlovsky V, Ajayi A, Colson PW, Hirsch-Moverman Y, El-Sadr W. Physician attitudes regarding bacille Calmette-Guerin vaccination and treatment of latent tuberculosis infection. Int J Tuberc Lung Dis. 2004;8(12):1443–7.PubMed Salazar-Schicchi J, Jedlovsky V, Ajayi A, Colson PW, Hirsch-Moverman Y, El-Sadr W. Physician attitudes regarding bacille Calmette-Guerin vaccination and treatment of latent tuberculosis infection. Int J Tuberc Lung Dis. 2004;8(12):1443–7.PubMed
28.
go back to reference Institute of Medicine. Ending neglect: the elimination of tuberculosis in the United States 2000. Geiter L, editor. Committee on the Elimination of Tuberculosis in the United States, Division of Health Promotion and Disease Prevention. Washigton, DC: National Academy Press. Institute of Medicine. Ending neglect: the elimination of tuberculosis in the United States 2000. Geiter L, editor. Committee on the Elimination of Tuberculosis in the United States, Division of Health Promotion and Disease Prevention. Washigton, DC: National Academy Press.
30.
go back to reference Styblo K. Epidemiology of tuberculosis. Selected papers, vol 24. The Hague, The Netherlands: Royal Netherlands Tuberculosis Association (KNCV); 1991. p. 49–50. Styblo K. Epidemiology of tuberculosis. Selected papers, vol 24. The Hague, The Netherlands: Royal Netherlands Tuberculosis Association (KNCV); 1991. p. 49–50.
31.
go back to reference Bennett D, Couval JM, Onorato MD, et al. Prevalence of TB infection in the US population 1999–2000. In: Program and abstracts of the American Public Health Association 131st annual meeting; San Francisco, California, November 15–19, 2003. Session 4199. Bennett D, Couval JM, Onorato MD, et al. Prevalence of TB infection in the US population 1999–2000. In: Program and abstracts of the American Public Health Association 131st annual meeting; San Francisco, California, November 15–19, 2003. Session 4199.
Metadata
Title
Multi-Level Barriers to LTBI Treatment: A Research Note
Authors
Linda Hill
Elaine Blumberg
Carol Sipan
Katharine Schmitz
Joshua West
Norma Kelley
Melbourne Hovell
Publication date
01-08-2010
Publisher
Springer US
Published in
Journal of Immigrant and Minority Health / Issue 4/2010
Print ISSN: 1557-1912
Electronic ISSN: 1557-1920
DOI
https://doi.org/10.1007/s10903-008-9216-5

Other articles of this Issue 4/2010

Journal of Immigrant and Minority Health 4/2010 Go to the issue