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Published in: Journal of Genetic Counseling 2/2017

01-04-2017 | Original Research

A Psycho-Educational Intervention for People with a Family History of Depression: Pilot Results

Published in: Journal of Genetic Counseling | Issue 2/2017

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Abstract

We developed and pilot-tested the first online psycho-educational intervention that specifically targets people with a family history of depression (‘LINKS’). LINKS provides genetic risk information and evidence-rated information on preventive strategies for depression and incorporates a risk assessment tool and several videos using professional actors. LINKS was pilot-tested in the general practitioner (GP) setting. The patient sample included people with a family history of at least one first-degree relative (FDR) with major depressive disorder (MDD) or bipolar disorder (BD). Patients attending participating GP practices were invited to enroll in the study by letter from their GP. Patients who self-identified as having at least one first-degree relative (FDR) with MDD or BD were eligible. Patients completed questionnaires, pre-post viewing LINKS, with measures assessing satisfaction, relevance, emotional impact and perceived improvement of understanding. Six GP practices participated, and 24 patients completed both questionnaires. Of these, all reported that they were satisfied or very satisfied with LINKS, and 74 % reported that LINKS met their expectations, and 21 % that it exceeded their expectations. LINKS was judged highly acceptable by this sample of GP attendees, and results indicate that an assessment of its effectiveness in a larger controlled trial is warranted.
Literature
go back to reference Andersson, G., & Hedman, E. (2013). Effectiveness of guided internet-based cognitive behavior therapy in regular clinical settings. Verhaltenstherapie, 23, 140–148.CrossRef Andersson, G., & Hedman, E. (2013). Effectiveness of guided internet-based cognitive behavior therapy in regular clinical settings. Verhaltenstherapie, 23, 140–148.CrossRef
go back to reference Barrera, A., Torres, L., & Munoz, R. (2007). Prevention of depression: the state of the science at the beginning of the twenty-first century. International Review of Psychiatry, 19, 655–670.CrossRefPubMed Barrera, A., Torres, L., & Munoz, R. (2007). Prevention of depression: the state of the science at the beginning of the twenty-first century. International Review of Psychiatry, 19, 655–670.CrossRefPubMed
go back to reference Barrera, A., Beekman, A. T., & Reynolds, C. (2012). Prevention of depression: a global priority. JAMA, 307, 2259.CrossRef Barrera, A., Beekman, A. T., & Reynolds, C. (2012). Prevention of depression: a global priority. JAMA, 307, 2259.CrossRef
go back to reference Beardslee, W., Brent, D., Weersing, V., et al. (2013). Prevention of depression in at-risk adolescents: longer-term effects. JAMA Psychiatry, 70, 1161–1170.CrossRefPubMedPubMedCentral Beardslee, W., Brent, D., Weersing, V., et al. (2013). Prevention of depression in at-risk adolescents: longer-term effects. JAMA Psychiatry, 70, 1161–1170.CrossRefPubMedPubMedCentral
go back to reference Berk, M., Sanders, K., Pasco, J., et al. (2007). Vitamin D deficiency may play a role in depression. Medical Hypotheses, 69, 1316–1319.CrossRefPubMed Berk, M., Sanders, K., Pasco, J., et al. (2007). Vitamin D deficiency may play a role in depression. Medical Hypotheses, 69, 1316–1319.CrossRefPubMed
go back to reference Biesecker, B., & Peay, H. (2003). Ethical issues in psychiatric genetics research: points to consider. Psychopharmacology, 171, 27–35.CrossRefPubMed Biesecker, B., & Peay, H. (2003). Ethical issues in psychiatric genetics research: points to consider. Psychopharmacology, 171, 27–35.CrossRefPubMed
go back to reference Clarke, G., Hornbrook, M., Lynch, F., et al. (2001). A randomised trial of a group cognitive intervention for depression in adolsecent offspring of depressed patients. Archives of General Psychiatry, 58, 1127–1134.CrossRefPubMed Clarke, G., Hornbrook, M., Lynch, F., et al. (2001). A randomised trial of a group cognitive intervention for depression in adolsecent offspring of depressed patients. Archives of General Psychiatry, 58, 1127–1134.CrossRefPubMed
go back to reference Cuijpers, P., van Straten, A., Smit, F., et al. (2008). Preventing the onset of depressive disorders: a meta-analytic review of psychological interventions. American Journal of Psychiatry, 165, 1272–1280.CrossRefPubMed Cuijpers, P., van Straten, A., Smit, F., et al. (2008). Preventing the onset of depressive disorders: a meta-analytic review of psychological interventions. American Journal of Psychiatry, 165, 1272–1280.CrossRefPubMed
go back to reference Cuijpers, P., Donker, T., Johansson, R., et al. (2011). Self-Guided Psychological Treatment for Depressive Symptoms: A Meta-Analysis PLOS ONE, 6, e21274.PubMed Cuijpers, P., Donker, T., Johansson, R., et al. (2011). Self-Guided Psychological Treatment for Depressive Symptoms: A Meta-Analysis PLOS ONE, 6, e21274.PubMed
go back to reference Davis, L., Uezato, A., Newell, J., et al. (2008). Major depression and comorbid substance use disorders. Current Opinion in Psychiatry, 21, 14–18.CrossRefPubMed Davis, L., Uezato, A., Newell, J., et al. (2008). Major depression and comorbid substance use disorders. Current Opinion in Psychiatry, 21, 14–18.CrossRefPubMed
go back to reference Department of Health and Ageing (2013). National Mental Health Report 2013: Tracking progress of mental health reform in Australia, 1993–2011. Canberra: Commonwealth of Australia. Department of Health and Ageing (2013). National Mental Health Report 2013: Tracking progress of mental health reform in Australia, 1993–2011. Canberra: Commonwealth of Australia.
go back to reference Donker, T., Griffiths, K., Cuijper, P., et al. (2009). Psychoeducation for depression, anxiety and psychological distress: a meta-analysis. BMC Medicine, 2009(7), 79.CrossRef Donker, T., Griffiths, K., Cuijper, P., et al. (2009). Psychoeducation for depression, anxiety and psychological distress: a meta-analysis. BMC Medicine, 2009(7), 79.CrossRef
go back to reference Ebert, D., Zarski, A., Christensen, H., et al. (2015). Internet and computer-based cognitive behavioral therapy for anxiety and depression in youth: a meta-analysis of randomized controlled outcome trials. PloS One, 10, e0119895.CrossRefPubMedPubMedCentral Ebert, D., Zarski, A., Christensen, H., et al. (2015). Internet and computer-based cognitive behavioral therapy for anxiety and depression in youth: a meta-analysis of randomized controlled outcome trials. PloS One, 10, e0119895.CrossRefPubMedPubMedCentral
go back to reference Garber, J., Clarke, G., & Weersing, R. (2009). Prevention of depression in at-risk adolescents: a randomised controlled trial. Journal of the American Medical Association, 301, 2215–2224.CrossRefPubMedPubMedCentral Garber, J., Clarke, G., & Weersing, R. (2009). Prevention of depression in at-risk adolescents: a randomised controlled trial. Journal of the American Medical Association, 301, 2215–2224.CrossRefPubMedPubMedCentral
go back to reference Gates, S., Williams, M., Withers, E., et al. (2009). Does a monetary incentive improve the response to a postal questionnaire in a randomised controlled trial? The MINT incentive study. Trials, 10. doi:10.1186/1745-6215-1110-1144. Gates, S., Williams, M., Withers, E., et al. (2009). Does a monetary incentive improve the response to a postal questionnaire in a randomised controlled trial? The MINT incentive study. Trials, 10. doi:10.​1186/​1745-6215-1110-1144.
go back to reference Jacobs, M., Miller, L., Wickramaratne, P., et al. (2012). Family religion and psychopathology in children of depressed mothers: ten-year follow-up. Journal of Affective Disorders, 136, 320–327.CrossRefPubMed Jacobs, M., Miller, L., Wickramaratne, P., et al. (2012). Family religion and psychopathology in children of depressed mothers: ten-year follow-up. Journal of Affective Disorders, 136, 320–327.CrossRefPubMed
go back to reference Jorm, A. F., Barney, L. J., Christensen, H., et al. (2006). Research on mental health literacy: what we know and what we still need to know. Australian and New Zealand Journal of Psychiatry, 40, 3–5.CrossRefPubMed Jorm, A. F., Barney, L. J., Christensen, H., et al. (2006). Research on mental health literacy: what we know and what we still need to know. Australian and New Zealand Journal of Psychiatry, 40, 3–5.CrossRefPubMed
go back to reference Kasen, S., Wickramaratne, P., Gameroff, M., et al. (2012). Religiosity and resilience in persons at high risk for major depression. Psychological Medicine, 42, 509–519.CrossRefPubMed Kasen, S., Wickramaratne, P., Gameroff, M., et al. (2012). Religiosity and resilience in persons at high risk for major depression. Psychological Medicine, 42, 509–519.CrossRefPubMed
go back to reference Kieseppa, T., Partonen, T., Haukka, J., et al. (2004). High concordance of bipolar I disorder in a nationwide sample of twins. American Journal of Psychiatry, 161, 1814–1821.CrossRefPubMed Kieseppa, T., Partonen, T., Haukka, J., et al. (2004). High concordance of bipolar I disorder in a nationwide sample of twins. American Journal of Psychiatry, 161, 1814–1821.CrossRefPubMed
go back to reference Larun L, Nordheim L, Ekeland E, et al. (2006) Exercise in prevention and treatment of anxiety and depression among children and young people. Cochrane Database of Systematic Reviews. Larun L, Nordheim L, Ekeland E, et al. (2006) Exercise in prevention and treatment of anxiety and depression among children and young people. Cochrane Database of Systematic Reviews.
go back to reference Mackinnon, A., Griffiths, K., & Christensen, H. (2008). Comparative randomised trial of online cognitive–behavioural therapy and an information website for depression: 12-month outcomes. British Journal of Psychiatry, 192, 130–134.CrossRefPubMed Mackinnon, A., Griffiths, K., & Christensen, H. (2008). Comparative randomised trial of online cognitive–behavioural therapy and an information website for depression: 12-month outcomes. British Journal of Psychiatry, 192, 130–134.CrossRefPubMed
go back to reference Marry S, McDowell H, Hetrick S, et al. (2004) Psychological and/or educational interventions for the prevention of depression in children and adolescents. Cochrane Database of Systematic Reviews.CrossRef Marry S, McDowell H, Hetrick S, et al. (2004) Psychological and/or educational interventions for the prevention of depression in children and adolescents. Cochrane Database of Systematic Reviews.CrossRef
go back to reference Meiser, B., Schofield, P., Trevena, L., et al. (2013). Cluster randomized controlled trial of a psycho-educational intervention for people with a family history of depression for use in general practice. BMC Psychiatry, 13. Meiser, B., Schofield, P., Trevena, L., et al. (2013). Cluster randomized controlled trial of a psycho-educational intervention for people with a family history of depression for use in general practice. BMC Psychiatry, 13.
go back to reference Munoz, R., Cuijpers, P., Smit, F., et al. (2010). Prevention of major depression. Annual Review of Clinical Psychology, 6, 181–212.CrossRefPubMed Munoz, R., Cuijpers, P., Smit, F., et al. (2010). Prevention of major depression. Annual Review of Clinical Psychology, 6, 181–212.CrossRefPubMed
go back to reference National Health & Medical Research Council. (1999). How to present the evidence for consumers. Canberra: Commonwealth of Australia. National Health & Medical Research Council. (1999). How to present the evidence for consumers. Canberra: Commonwealth of Australia.
go back to reference Peay, H., & Austin, J. (2011). How to talk with families about genetics and psychiatric illness. New York: W.W. Norton Company Inc.. Peay, H., & Austin, J. (2011). How to talk with families about genetics and psychiatric illness. New York: W.W. Norton Company Inc..
go back to reference Peay, H., Hooker, G., Kassem, L., et al. (2009). Family risk and related education and counseling needs: perceptions of adults with bipolar disorder and siblings of adults with bipolar disorder. American Journal of Medical Genetics Part A., 149 A, 364–371.CrossRef Peay, H., Hooker, G., Kassem, L., et al. (2009). Family risk and related education and counseling needs: perceptions of adults with bipolar disorder and siblings of adults with bipolar disorder. American Journal of Medical Genetics Part A., 149 A, 364–371.CrossRef
go back to reference Perlman, C., Johnson, S., & Mellmand, T. (2006). The prospective impact of sleep duration on depression and mania. Bipolar Disorders, 8, 271–274.CrossRefPubMed Perlman, C., Johnson, S., & Mellmand, T. (2006). The prospective impact of sleep duration on depression and mania. Bipolar Disorders, 8, 271–274.CrossRefPubMed
go back to reference Quinn, V., Wilde, A., Meiser, B., et al. (2014). Preferences regarding targeted education and risk assessment in people with a family history of major depressive disorder. Journal of Genetic Counseling, 23, 785–795.CrossRefPubMed Quinn, V., Wilde, A., Meiser, B., et al. (2014). Preferences regarding targeted education and risk assessment in people with a family history of major depressive disorder. Journal of Genetic Counseling, 23, 785–795.CrossRefPubMed
go back to reference Seligman, M., Steen, T., Park, N., et al. (2005). Positive psychology progress: empirical validation of interventions. American Psychologist, 60, 410–421.CrossRefPubMed Seligman, M., Steen, T., Park, N., et al. (2005). Positive psychology progress: empirical validation of interventions. American Psychologist, 60, 410–421.CrossRefPubMed
go back to reference Skarupski K, Tangney C, Li H, et al. (2013) Mediterranean diet and depressive symptoms over time. Journal of Nutrition, Health and Aging 17. Skarupski K, Tangney C, Li H, et al. (2013) Mediterranean diet and depressive symptoms over time. Journal of Nutrition, Health and Aging 17.
go back to reference Stice, E., Ragan, J., & Randall, P. (2004). Prospective relations between social support and depression: differential direction of effects for parent and peer support? Journal of Abnormal Psychology, 113, 155–159.CrossRefPubMed Stice, E., Ragan, J., & Randall, P. (2004). Prospective relations between social support and depression: differential direction of effects for parent and peer support? Journal of Abnormal Psychology, 113, 155–159.CrossRefPubMed
go back to reference Sullivan, P., Neale, M., & Kendler, K. (2000). Genetic epidemiology of major depression: review and meta-analysis. American Journal of Psychiatry, 157, 1552–1562.CrossRefPubMed Sullivan, P., Neale, M., & Kendler, K. (2000). Genetic epidemiology of major depression: review and meta-analysis. American Journal of Psychiatry, 157, 1552–1562.CrossRefPubMed
go back to reference Trevena, L., Irwig, L., & Barratt, A. (2006). Impact of privacy legislation on the number and characteristics of people who are recruited for research: a randomised controlled trial. Journal of Medical Ethics, 32, 473–477.CrossRefPubMedPubMedCentral Trevena, L., Irwig, L., & Barratt, A. (2006). Impact of privacy legislation on the number and characteristics of people who are recruited for research: a randomised controlled trial. Journal of Medical Ethics, 32, 473–477.CrossRefPubMedPubMedCentral
go back to reference Wakefield, C., Meiser, B., Homewood, J., et al. (2007). Development and pilot testing of two decision aids for individuals considering genetic testing for cancer risk. Journal of Genetic Counseling, 16, 325–339.CrossRefPubMed Wakefield, C., Meiser, B., Homewood, J., et al. (2007). Development and pilot testing of two decision aids for individuals considering genetic testing for cancer risk. Journal of Genetic Counseling, 16, 325–339.CrossRefPubMed
go back to reference Weissman, M., Wickramaratne, P., Adams, P., et al. (2000). Brief screening for family psychiatric history: the family history screen. Archives of General Psychiatry, 57, 675–682.CrossRefPubMed Weissman, M., Wickramaratne, P., Adams, P., et al. (2000). Brief screening for family psychiatric history: the family history screen. Archives of General Psychiatry, 57, 675–682.CrossRefPubMed
go back to reference Wilde, A., Chan, H., Rahman, B., et al. (2014). A meta-analysis of the risk of major affective disorder in relatives of individuals affected by major depressive disorder or bipolar disorder. Journal of Affective Disorders, 158, 37–47.CrossRefPubMed Wilde, A., Chan, H., Rahman, B., et al. (2014). A meta-analysis of the risk of major affective disorder in relatives of individuals affected by major depressive disorder or bipolar disorder. Journal of Affective Disorders, 158, 37–47.CrossRefPubMed
Metadata
Title
A Psycho-Educational Intervention for People with a Family History of Depression: Pilot Results
Publication date
01-04-2017
Published in
Journal of Genetic Counseling / Issue 2/2017
Print ISSN: 1059-7700
Electronic ISSN: 1573-3599
DOI
https://doi.org/10.1007/s10897-016-0011-5

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