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Published in: Journal of Genetic Counseling 5/2015

Open Access 01-10-2015 | Original Research

Do Attachment Style and Emotion Regulation Strategies Indicate Distress in Predictive Testing?

Authors: Lucienne B. van der Meer, Erik van Duijn, Erik J. Giltay, Aad Tibben

Published in: Journal of Genetic Counseling | Issue 5/2015

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Abstract

Predictive genetic testing for a neurogenetic disorder evokes strong emotions, and may lead to distress. The aim of this study is to investigate whether attachment style and emotion regulation strategies are associated with distress in persons who present for predictive testing for a neurogenetic disorder, and whether these psychological traits predict distress after receiving test results. Self-report scales were used to assess attachment insecurity (anxiety and avoidance) and maladaptive emotion regulation strategies (self-blame, rumination, catastrophizing) in adults at 50 % risk for Huntington’s Disease (HD), Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), and Hereditary Cerebral Hemorrhage With Amyloidosis - Dutch type (HCHWA-D), when they presented for predictive testing. Distress was measured before testing and twice (within 2 months and between 6 and 8 months) after receiving test results. Pearson correlations and linear regression were used to analyze whether attachment style and emotion regulation strategies indicated distress. In 98 persons at risk for HD, CADASIL, or HCHWA-D, attachment anxiety and catastrophizing were associated with distress before predictive testing. Attachment anxiety predicted distress up to 2 months after testing. Clinicians may consider looking for signs of attachment anxiety and catastrophizing in persons who present for predictive testing, to see who may be vulnerable for distress during and after testing.
Literature
go back to reference Ainsworth, M. D. S., Blehar, M. C., Waters, E., & Wall, S. (1978). Patterns of attachment: A psychological study of the strange situation. Oxford England: Lawrence Erlbaum. Ainsworth, M. D. S., Blehar, M. C., Waters, E., & Wall, S. (1978). Patterns of attachment: A psychological study of the strange situation. Oxford England: Lawrence Erlbaum.
go back to reference Bennett, P., Wilkinson, C., Turner, J., Brain, K., Edwards, R. T., Griffith, G., et al. (2008). Psychological factors associated with emotional responses to receiving genetic risk information. Journal of Genetic Counseling, 17, 234–241.CrossRef Bennett, P., Wilkinson, C., Turner, J., Brain, K., Edwards, R. T., Griffith, G., et al. (2008). Psychological factors associated with emotional responses to receiving genetic risk information. Journal of Genetic Counseling, 17, 234–241.CrossRef
go back to reference Bowlby, J. (1973). Attachment and loss (Vol. II: Separation, anxiety and anger). London: Hogarth Press. Bowlby, J. (1973). Attachment and loss (Vol. II: Separation, anxiety and anger). London: Hogarth Press.
go back to reference Brennan, K. A., Clark, C. L., & Shaver, P. R. (1998). Self-report measurement of adult attachment: An integrative overview. In J. A. Simpson, W. S. Rholes, J. A. Simpson, & W. S. Rholes (Eds.), Attachment theory and close relationships (pp. 46–76). New York: Guilford Press. Brennan, K. A., Clark, C. L., & Shaver, P. R. (1998). Self-report measurement of adult attachment: An integrative overview. In J. A. Simpson, W. S. Rholes, J. A. Simpson, & W. S. Rholes (Eds.), Attachment theory and close relationships (pp. 46–76). New York: Guilford Press.
go back to reference De Beurs, E., & Zitman, F. (2005). The Brief Symptom Inventory (BSI): Reliability and validity of a practical alternative to SCL-90. Maandblad Geestelijke volksgezondheid, 61, 120–141. De Beurs, E., & Zitman, F. (2005). The Brief Symptom Inventory (BSI): Reliability and validity of a practical alternative to SCL-90. Maandblad Geestelijke volksgezondheid, 61, 120–141.
go back to reference Derogatis, L. R. (1975). The Brief Symptom Inventory. Baltimore: Clinical Psychometric Research. Derogatis, L. R. (1975). The Brief Symptom Inventory. Baltimore: Clinical Psychometric Research.
go back to reference Dufrasne, S., Roy, M., Galvez, M., & Rosenblatt, D. S. (2011). Experience over fifteen years with a protocol for predictive testing for Huntington disease. Molecular Genetics and Metabolism, 102, 494–504.CrossRef Dufrasne, S., Roy, M., Galvez, M., & Rosenblatt, D. S. (2011). Experience over fifteen years with a protocol for predictive testing for Huntington disease. Molecular Genetics and Metabolism, 102, 494–504.CrossRef
go back to reference Fraley, R. C., & Shaver, P. R. (2000). Adult romantic attachment: theoretical developments, emerging controversies, and unanswered questions. Review of General Psychology, 4, 132–154.CrossRef Fraley, R. C., & Shaver, P. R. (2000). Adult romantic attachment: theoretical developments, emerging controversies, and unanswered questions. Review of General Psychology, 4, 132–154.CrossRef
go back to reference Fraley, R. C., Waller, N. G., & Brennan, K. A. (2000). An item response theory analysis of self-report measures of adult attachment. Journal of Personality and Social Psychology, 78, 350–365.CrossRef Fraley, R. C., Waller, N. G., & Brennan, K. A. (2000). An item response theory analysis of self-report measures of adult attachment. Journal of Personality and Social Psychology, 78, 350–365.CrossRef
go back to reference Garnefski, N., & Kraaij, V. (2006). Relationships between cognitive emotion regulation strategies and depressive symptoms: a comparative study of five specific samples. Personality and Individual Differences, 40, 1659–1669.CrossRef Garnefski, N., & Kraaij, V. (2006). Relationships between cognitive emotion regulation strategies and depressive symptoms: a comparative study of five specific samples. Personality and Individual Differences, 40, 1659–1669.CrossRef
go back to reference Garnefski, N., & Kraaij, V. (2009). Cognitive coping and psychological adjustment in different types of stressful life events. Individual Differences Research, 7, 168–181. Garnefski, N., & Kraaij, V. (2009). Cognitive coping and psychological adjustment in different types of stressful life events. Individual Differences Research, 7, 168–181.
go back to reference Garnefski, N., Kraaij, V., & Spinhoven, P. (2001). Negative life events, cognitive emotion regulation and emotional problems. Personality and Individual Differences, 30, 1311–1327.CrossRef Garnefski, N., Kraaij, V., & Spinhoven, P. (2001). Negative life events, cognitive emotion regulation and emotional problems. Personality and Individual Differences, 30, 1311–1327.CrossRef
go back to reference Garnefski, N., Kraaij, V., & Spinhoven, P. (2002). CERQ: Manual for the use of cognitive emotion regulation questionnaire. Leiderdorp: DATEC. Garnefski, N., Kraaij, V., & Spinhoven, P. (2002). CERQ: Manual for the use of cognitive emotion regulation questionnaire. Leiderdorp: DATEC.
go back to reference Grosfeld, F. J. M., Lips, C. J. M., Beemer, F. A., & ten Kroode, H. F. J. (2000). Who is at risk for psychological distress in genetic testing programs for hereditary cancer disorders? Journal of Genetic Counseling, 9, 253–266.CrossRef Grosfeld, F. J. M., Lips, C. J. M., Beemer, F. A., & ten Kroode, H. F. J. (2000). Who is at risk for psychological distress in genetic testing programs for hereditary cancer disorders? Journal of Genetic Counseling, 9, 253–266.CrossRef
go back to reference Gross, J. J., Richards, J. M., & John, O. P. (2006). Emotion regulation in everyday life. In D. K. Snyder, J. A. Simpson, & J. N. Hughes (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (1st ed., pp. 13–35). Washington: American Psychological Association.CrossRef Gross, J. J., Richards, J. M., & John, O. P. (2006). Emotion regulation in everyday life. In D. K. Snyder, J. A. Simpson, & J. N. Hughes (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (1st ed., pp. 13–35). Washington: American Psychological Association.CrossRef
go back to reference Herve, D., & Chabriat, H. (2010). CADASIL. Journal of Geriatric Psychiatry and Neurology, 23, 269–276.CrossRef Herve, D., & Chabriat, H. (2010). CADASIL. Journal of Geriatric Psychiatry and Neurology, 23, 269–276.CrossRef
go back to reference Maat-Schieman, M., Roos, R., & van Duinen, S. (2005). Hereditary cerebral hemorrhage with amyloidosis-Dutch type. Neuropathology, 25, 288–297.CrossRef Maat-Schieman, M., Roos, R., & van Duinen, S. (2005). Hereditary cerebral hemorrhage with amyloidosis-Dutch type. Neuropathology, 25, 288–297.CrossRef
go back to reference MacLeod, R., Tibben, A., Frontali, M., Evers-Kiebooms, G., Jones, A., Martinez-Descales, A., et al. (2013). Recommendations for the predictive genetic test in Huntington’s disease. Clinical Genetics, 83, 221–231.CrossRef MacLeod, R., Tibben, A., Frontali, M., Evers-Kiebooms, G., Jones, A., Martinez-Descales, A., et al. (2013). Recommendations for the predictive genetic test in Huntington’s disease. Clinical Genetics, 83, 221–231.CrossRef
go back to reference Mikulincer, M., & Shaver, P. R. (2003). The attachment behavioral system in adulthood: Activation, psychodynamics, and interpersonal processes. In M. P. Zanna (Ed.), Advances in experimental social psychology (Vol. 35, pp. 53–152). San Diego: Elsevier Academic Press. Mikulincer, M., & Shaver, P. R. (2003). The attachment behavioral system in adulthood: Activation, psychodynamics, and interpersonal processes. In M. P. Zanna (Ed.), Advances in experimental social psychology (Vol. 35, pp. 53–152). San Diego: Elsevier Academic Press.
go back to reference Mikulincer, M., & Shaver, P. R. (2008). Adult attachment and affect regulation. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment (2nd ed., pp. 503–531). New York: Guilford Press. Mikulincer, M., & Shaver, P. R. (2008). Adult attachment and affect regulation. In J. Cassidy & P. R. Shaver (Eds.), Handbook of attachment (2nd ed., pp. 503–531). New York: Guilford Press.
go back to reference Mikulincer, M., Shaver, P. R., & Horesh, N. (2006). Attachment bases of emotion regulation and posttraumatic adjustment. In D. K. Snyder, J. A. Simpson, & J. N. Hughes (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (1st ed., pp. 77–99). Washington: American Psychological Association.CrossRef Mikulincer, M., Shaver, P. R., & Horesh, N. (2006). Attachment bases of emotion regulation and posttraumatic adjustment. In D. K. Snyder, J. A. Simpson, & J. N. Hughes (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (1st ed., pp. 77–99). Washington: American Psychological Association.CrossRef
go back to reference Pasacreta, J. V. (2003). Psychosocial issues associated with genetic testing for breast and ovarian cancer risk: an integrative review. Cancer Investigation, 21, 588–623.CrossRef Pasacreta, J. V. (2003). Psychosocial issues associated with genetic testing for breast and ovarian cancer risk: an integrative review. Cancer Investigation, 21, 588–623.CrossRef
go back to reference Pascuzzo, K., Cyr, C., & Moss, E. (2013). Longitudinal association between adolescent attachment, adult romantic attachment, and emotion regulation strategies. Attachment & Human Development, 15, 83–103.CrossRef Pascuzzo, K., Cyr, C., & Moss, E. (2013). Longitudinal association between adolescent attachment, adult romantic attachment, and emotion regulation strategies. Attachment & Human Development, 15, 83–103.CrossRef
go back to reference Pielage, S. B. (2006). Adult attachment and psychosocial functioning. Faculty of Behavioural and Social Sciences. University of Groningen. Pielage, S. B. (2006). Adult attachment and psychosocial functioning. Faculty of Behavioural and Social Sciences. University of Groningen.
go back to reference Pietromonaco, P., Feldman Barrett, L., & Powers, S. I. (2006). Adult attachment theory and affective reactivity and regulation. In D. K. Snyder, J. A. Simpson, & J. N. Hughes (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (1st ed., pp. 57–74). Washington: American Psychological Association.CrossRef Pietromonaco, P., Feldman Barrett, L., & Powers, S. I. (2006). Adult attachment theory and affective reactivity and regulation. In D. K. Snyder, J. A. Simpson, & J. N. Hughes (Eds.), Emotion regulation in couples and families: Pathways to dysfunction and health (1st ed., pp. 57–74). Washington: American Psychological Association.CrossRef
go back to reference Reichelt, J. G., Moller, P., Heimdal, K., & Dahl, A. A. (2008). Psychological and cancer-specific distress at 18 months post-testing in women with demonstrated BRCA1 mutations for hereditary breast/ovarian cancer. Familial Cancer, 7, 245–254.CrossRef Reichelt, J. G., Moller, P., Heimdal, K., & Dahl, A. A. (2008). Psychological and cancer-specific distress at 18 months post-testing in women with demonstrated BRCA1 mutations for hereditary breast/ovarian cancer. Familial Cancer, 7, 245–254.CrossRef
go back to reference Rolland, J. S., & Williams, J. K. (2005). Toward a biopsychosocial model for 21st-century genetics. Family Process, 44, 3–24.CrossRef Rolland, J. S., & Williams, J. K. (2005). Toward a biopsychosocial model for 21st-century genetics. Family Process, 44, 3–24.CrossRef
go back to reference Ross, C. A., & Tabrizi, S. J. (2011). Huntington’s disease: from molecular pathogenesis to clinical treatment. Lancet Neurology, 10, 83–98.CrossRef Ross, C. A., & Tabrizi, S. J. (2011). Huntington’s disease: from molecular pathogenesis to clinical treatment. Lancet Neurology, 10, 83–98.CrossRef
go back to reference Schulte-van Maaren, Y. W., Carlier, I. V., Zitman, F. G., van Hemert, A. M., de Waal, M. W., van Noorden, M. S., et al. (2012). Reference values for generic instruments used in routine outcome monitoring: the leiden routine outcome monitoring study. BMC Psychiatry, 12, 203.CrossRef Schulte-van Maaren, Y. W., Carlier, I. V., Zitman, F. G., van Hemert, A. M., de Waal, M. W., van Noorden, M. S., et al. (2012). Reference values for generic instruments used in routine outcome monitoring: the leiden routine outcome monitoring study. BMC Psychiatry, 12, 203.CrossRef
go back to reference Sibley, C. G., & Liu, J. H. (2004). Short-term temporal stability and factor structure of the revised experiences in close relationships (ECR-R) measure of adult attachment. Personality and Individual Differences, 36, 969–975.CrossRef Sibley, C. G., & Liu, J. H. (2004). Short-term temporal stability and factor structure of the revised experiences in close relationships (ECR-R) measure of adult attachment. Personality and Individual Differences, 36, 969–975.CrossRef
go back to reference Sroufe, L. A. (2005). Attachment and development: a prospective, longitudinal study from birth to adulthood. Attachment & Human Development, 7, 349–367.CrossRef Sroufe, L. A. (2005). Attachment and development: a prospective, longitudinal study from birth to adulthood. Attachment & Human Development, 7, 349–367.CrossRef
go back to reference Tibben, A. (2007). Predictive testing for Huntington’s disease. Brain Research Bulletin, 72, 165–171.CrossRef Tibben, A. (2007). Predictive testing for Huntington’s disease. Brain Research Bulletin, 72, 165–171.CrossRef
go back to reference van der Meer, L. B., Van Duijn, E., Wolterbeek, R., & Tibben, A. (2012). Adverse childhood experiences of persons at risk for Huntington’s disease or BRCA1/2 hereditary breast/ovarian cancer. Clinical Genetics, 81, 18–23.CrossRef van der Meer, L. B., Van Duijn, E., Wolterbeek, R., & Tibben, A. (2012). Adverse childhood experiences of persons at risk for Huntington’s disease or BRCA1/2 hereditary breast/ovarian cancer. Clinical Genetics, 81, 18–23.CrossRef
go back to reference van der Meer, L. B., Van Duijn, E., Wolterbeek, R., & Tibben, A. (2013). Offspring of a parent with genetic disease: childhood experiences and adult psychological characteristics. Health Psychol. van der Meer, L. B., Van Duijn, E., Wolterbeek, R., & Tibben, A. (2013). Offspring of a parent with genetic disease: childhood experiences and adult psychological characteristics. Health Psychol.
go back to reference Van Duijn, E., Kingma, E. M., Timman, R., Zitman, F. G., Tibben, A., Roos, R. A., et al. (2008). Cross-sectional study on prevalences of psychiatric disorders in mutation carriers of Huntington’s disease compared with mutation-negative first-degree relatives. Journal of Clinical Psychiatry, 69, 1804–1810.CrossRef Van Duijn, E., Kingma, E. M., Timman, R., Zitman, F. G., Tibben, A., Roos, R. A., et al. (2008). Cross-sectional study on prevalences of psychiatric disorders in mutation carriers of Huntington’s disease compared with mutation-negative first-degree relatives. Journal of Clinical Psychiatry, 69, 1804–1810.CrossRef
go back to reference van Oostrom, I., Meijers-Heijboer, H., Duivenvoorden, H. J., Brocker-Vriends, A. H., van Asperen, C. J., Sijmons, R. H., et al. (2007). Prognostic factors for hereditary cancer distress six months after BRCA1/2 or HNPCC genetic susceptibility testing. European Journal of Cancer, 43, 71–77.CrossRef van Oostrom, I., Meijers-Heijboer, H., Duivenvoorden, H. J., Brocker-Vriends, A. H., van Asperen, C. J., Sijmons, R. H., et al. (2007). Prognostic factors for hereditary cancer distress six months after BRCA1/2 or HNPCC genetic susceptibility testing. European Journal of Cancer, 43, 71–77.CrossRef
go back to reference Wei, M., Heppner, P. P., & Mallinckrodt, B. (2003). Perceived coping as a mediator between attachment and psychological distress: a structural equation modeling approach. Journal of Counseling Psychology, 50, 438–447.CrossRef Wei, M., Heppner, P. P., & Mallinckrodt, B. (2003). Perceived coping as a mediator between attachment and psychological distress: a structural equation modeling approach. Journal of Counseling Psychology, 50, 438–447.CrossRef
go back to reference Williams, J. K., Erwin, C., Juhl, A., Mills, J., Brossman, B., & Paulsen, J. S. (2010). Personal factors associated with reported benefits of Huntington disease family history or genetic testing. Genetic Testing and Molecular Biomarkers, 14, 629–636.CrossRef Williams, J. K., Erwin, C., Juhl, A., Mills, J., Brossman, B., & Paulsen, J. S. (2010). Personal factors associated with reported benefits of Huntington disease family history or genetic testing. Genetic Testing and Molecular Biomarkers, 14, 629–636.CrossRef
Metadata
Title
Do Attachment Style and Emotion Regulation Strategies Indicate Distress in Predictive Testing?
Authors
Lucienne B. van der Meer
Erik van Duijn
Erik J. Giltay
Aad Tibben
Publication date
01-10-2015
Publisher
Springer New York
Published in
Journal of Genetic Counseling / Issue 5/2015
Print ISSN: 1059-7700
Electronic ISSN: 1573-3599
DOI
https://doi.org/10.1007/s10897-015-9822-z

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