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Journal of Assisted Reproduction and Genetics

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Open Access 11-08-2023 | Turner's Syndrome | Fertility Preservation

Clinical pregnancy in Turner syndrome following re-implantation of cryopreserved ovarian cortex

Authors: CE Dunlop, SA Jack, EE Telfer, S. Zahra, RA Anderson

Published in: Journal of Assisted Reproduction and Genetics | Issue 10/2023

Abstract

Turner syndrome (TS) leads to a characteristic phenotype, including premature ovarian insufficiency and infertility. Ovarian tissue cryopreservation (OTC) is becoming an established fertility preservation strategy for both pre- and post-pubertal females and may offer the chance of having a biological family to selected patients with TS. To date, women with TS have had ovarian tissue cryopreserved but there are few reports of autologous re-implantation and none of pregnancy. We herein report, to our knowledge, the first clinical pregnancy in a patient with TS, conceived naturally following re-implantation of cryopreserved ovarian tissue which had been removed soon after spontaneous puberty. This provides proof of concept for OTC as a means of fertility preservation in TS.

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Title: Clinical pregnancy in Turner syndrome following re-implantation of cryopreserved ovarian cortex
Authors: CE Dunlop
SA Jack
EE Telfer
S. Zahra
RA Anderson
Publication date: 11-08-2023
Publisher: Springer US
Keywords: Turner's Syndrome
Fertility
Published in: Journal of Assisted Reproduction and Genetics / Issue 10/2023
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-023-02905-w

Keynote webinar | Spotlight on medication adherence

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Clinical pregnancy in Turner syndrome following re-implantation of cryopreserved ovarian cortex

Abstract

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Springer Medicine

Abstract

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