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Published in: Journal of Assisted Reproduction and Genetics 5/2018

01-05-2018 | Assisted Reproduction Technologies

First trimester pregnancy ultrasound findings as a function of method of conception in an infertile population

Authors: Frauke von Versen-Höynck, Jenna S. Petersen, Yueh-Yun Chi, Jing Liu, Valerie L. Baker

Published in: Journal of Assisted Reproduction and Genetics | Issue 5/2018

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Abstract

Purpose

The aim of this study was to determine whether first trimester ultrasound measurements of crown rump length (CRL) and gestational sac diameter (GSD) differ depending on the method of conception among infertile women.

Method

Infertile women, ages 21–50 years old, who conceived viable, singleton pregnancies via fresh embryo transfer (ET), frozen ET, non-in vitro fertilization (IVF) fertility treatment, or spontaneously were included in this observational cohort study at an academic fertility practice. Embryonic growth trajectories defined by the CRL and GSD at 6 and 8 weeks’ gestation were analyzed and compared among the methods of conception.

Results

Crown rump length at 6 weeks’ gestation was smaller for conceptions achieved via fresh ET compared with frozen ET in a natural cycle (1.50 vs. 2.50 mm, p = 0.017). Crown rump length was smaller at 8 weeks’ gestation in conceptions achieved via fresh ET compared to frozen ET in a programmed cycle (16.13 vs. 17.02 mm, p = 0.039).

Conclusion

Among infertile women, embryo growth may differ between fresh and frozen ET as early as 6 and 8 weeks’ gestation.
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Metadata
Title
First trimester pregnancy ultrasound findings as a function of method of conception in an infertile population
Authors
Frauke von Versen-Höynck
Jenna S. Petersen
Yueh-Yun Chi
Jing Liu
Valerie L. Baker
Publication date
01-05-2018
Publisher
Springer US
Published in
Journal of Assisted Reproduction and Genetics / Issue 5/2018
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-018-1120-x

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