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Journal of Assisted Reproduction and Genetics

Published in:

01-02-2013

Progress in understanding human ovarian folliculogenesis and its implications in assisted reproduction

Authors: Dong Zi Yang, Wan Yang, Yu Li, Zuanyu He

Published in: Journal of Assisted Reproduction and Genetics | Issue 2/2013

Abstract

Purpose

To highlight recent progress in understanding the pattern of follicular wave emergence of human menstrual cycle, providing a brief overview of the new options for human ovarian stimulation and oocyte retrieval by making full use of follicular physiological waves of the patients either with normal or abnormal ovarian reserve.

Methods

Literature review and editorial commentary.

Results

There has been increasing evidence to suggest that multiple (two or three) antral follicular waves are recruited during human menstrual cycle. The treatment regimens designed based on the theory of follicular waves, to promote increased success with assisted reproduction technology (ART) and fertility preservation have been reported. These new options for human ovarian stimulation and oocyte retrieval by making full use of follicular waves of the patients either with normal or abnormal ovarian reserve lead to new thinking about the standard protocols in ART and challenge the traditional theory that a single wave of antral follicles grows only during the follicular phase of the menstrual cycle.

Conclusions

The understanding of human ovarian folliculogenesis may have profound implications in ART and fertility preservation. Further studies are needed to evaluate the optimal regimens in ART based on the theory of follicular waves and to identify non-invasive markers for predicting the outcome and the potential utilities of follicles obtained from anovulatory follicular waves in ART.

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Title: Progress in understanding human ovarian folliculogenesis and its implications in assisted reproduction
Authors: Dong Zi Yang
Wan Yang
Yu Li
Zuanyu He
Publication date: 01-02-2013
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 2/2013
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-013-9944-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Progress in understanding human ovarian folliculogenesis and its implications in assisted reproduction

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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