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Journal of Assisted Reproduction and Genetics

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01-03-2012 | ASSISTED REPRODUCTION TECHNOLOGIES

Elevated day 3 FSH/LH ratio: a marker to predict IVF outcome in young and older women

Authors: Berna Seckin, Figen Turkcapar, Gulnur Ozaksit

Published in: Journal of Assisted Reproduction and Genetics | Issue 3/2012

Abstract

Purpose

To evaluate the value of elevated day 3 FSH/LH ratio in predicting IVF results in young and older women.

Methods

One hundred seventy-four women with normal day 3 FSH levels undergoing IVF treatment were studied. Patients were divided into two groups according to basal FSH/LH ratio: Group 1(FSH/LH ≥3, n = 43) and Group 2 (FSH/LH <3, n = 131). The effects of FSH/LH ratio on IVF outcomes were compared. Also, the impact of elevated FSH/LH levels on younger (<35 years; n = 113) and older (≥35 years; n = 61) women was evaluated.

Results

Group 1 had significantly lower mean day 3 LH levels (p = 0.001), lower number of oocytes retrieved (p = 0.004) and lower clinical pregnancy rate (p = 0.04). Older women with elevated FSH/LH ratio (n = 23) had significantly lower transferred good grade embryo counts (p = 0.04) and lower pregnancy rate (p = 0.03) versus older women with lower FSH/LH ratio. But in younger women treatment outcomes were similar in both subgroups.

Conclusion

Elevated day 3 FSH/LH ratio is useful in predicting IVF outcome in older women, but does not seem to be an accurate predictor in younger women.

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Title: Elevated day 3 FSH/LH ratio: a marker to predict IVF outcome in young and older women
Authors: Berna Seckin
Figen Turkcapar
Gulnur Ozaksit
Publication date: 01-03-2012
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 3/2012
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-011-9695-5

At a glance: The STEP trials

Springer Medicine

Elevated day 3 FSH/LH ratio: a marker to predict IVF outcome in young and older women

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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