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Journal of Assisted Reproduction and Genetics

Published in:

01-02-2012 | ASSISTED REPRODUCTION TECHNOLOGIES

Severe ovarian hyperstimulation syndrome after letrozole-gonadotropin stimulation: a case report

Authors: Jayeon Kim, Anne Z. Steiner, Marc Fritz, Jennifer E. Mersereau

Published in: Journal of Assisted Reproduction and Genetics | Issue 2/2012

Excerpt

Ovarian hyperstimulation syndrome (OHSS) results from an exaggerated response to ovulation induction, characterized by a fluid shift from the intravascular space to third space compartments. The incidence of moderate OHSS is approximately 3–6% and severe OHSS occurs in 0.1–3% of treatment cycles [1, 2]. A number of causal mechanisms have been investigated, involving estradiol (E₂), human chorionic gonadotropin (hCG), and vascular endothelial growth factor (VEGF). A strong association between E₂ concentrations and risk for developing OHSS has been observed consistently [3]. …

Delvigne A, Rozenberg S. Epidemiology and prevention of ovarian hyperstimulation syndrome (OHSS): a review. Hum Reprod Update. 2002;8(6):559–77.PubMedCrossRef

Vlahos NF, Gregoriou O. Prevention and management of ovarian hyperstimulation syndrome. Ann N Y Acad Sci. 2006;1092:247–64.PubMedCrossRef

Asch RH, Li HP, Balmaceda JP, Weckstein LN, Stone SC. Severe ovarian hyperstimulation syndrome in assisted reproductive technology: definition of high risk groups. Hum Reprod. 1991;6(10):1395–9.PubMed

Oktay K, Hourvitz A, Sahin G, Oktem O, Safro B, Cil A, et al. Letrozole reduces estrogen and gonadotropin exposure in women with breast cancer undergoing ovarian stimulation before chemotherapy. J Clin Endocrinol Metab. 2006;91(10):3885–90.PubMedCrossRef

Practice Committee of American Society for Reproductive Medicine. Ovarian hyperstimulation syndrome. Fertil Steril. 2008;90(5 Suppl):S188–93.

Shetty G, Krishnamurthy H, Krishnamurthy HN, Bhatnagar S, Moudgal RN. Effect of estrogen deprivation on the reproductive physiology of male and female primates. J Steroid Biochem Mol Biol. 1997;61(3–6):157–66.PubMedCrossRef

Badawy A, Elnashar A, Totongy M. Clomiphene citrate or aromatase inhibitors combined with gonadotropins for superovulation in women undergoing intrauterine insemination: a prospective randomised trial. J Obstet Gynaecol;30(6):617–21.

Oktay K, Turkcuoglu I, Rodriguez-Wallberg KA. GnRH agonist trigger for women with breast cancer undergoing fertility preservation by aromatase inhibitor/FSH stimulation. Reprod Biomed Online;20(6):783–8.

Aboulghar MA, Mansour RT. Ovarian hyperstimulation syndrome: classifications and critical analysis of preventive measures. Hum Reprod Update. 2003;9(3):275–89.PubMedCrossRef

Title: Severe ovarian hyperstimulation syndrome after letrozole-gonadotropin stimulation: a case report
Authors: Jayeon Kim
Anne Z. Steiner
Marc Fritz
Jennifer E. Mersereau
Publication date: 01-02-2012
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 2/2012
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-011-9676-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Severe ovarian hyperstimulation syndrome after letrozole-gonadotropin stimulation: a case report

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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