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Journal of Assisted Reproduction and Genetics

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01-05-2009 | ASSISTED REPRODUCTION

Follicular and luteal phase endometrial thickness and echogenic pattern and pregnancy outcome in oocyte donation cycles

Authors: Matthew A. Barker, Lynn M. Boehnlein, Peter Kovacs, Steven R. Lindheim

Published in: Journal of Assisted Reproduction and Genetics | Issue 5/2009

Abstract

Purpose

To study the effect of endometrial thickness (ET) and echogenic pattern (EP) in oocyte donation cycles upon pregnancy outcomes.

Methods

Seventy-nine cycles resulting in blastocyst embryo transfer were evaluated. Donors underwent ovarian hyperstimulation using rFSH and GnRH-antagonist. Recipients were synchronized to donors using GnRH-agonist down-regulation followed by fixed dose of estrogen (E2) and progesterone (P4) following hCG. Transvaginal ultrasound (US) obtained ET and EP 10-11 days after initiation of E2 and on day of embryo transfer. Primary outcome was ET and EP in pregnant and non-pregnant cycles. Stimulation and embryology data was analyzed in donors to assess differences prior to transfer.

Results

Fifty-nine cycles resulted in clinical pregnancy. No differences were observed in pregnant vs. non-pregnant cycles in proliferative or secretory ET and EP. Similar baseline and stimulation characteristics were found in pregnant and non-pregnant cycles. Regression analysis showed end thickness were not predictive of pregnancy outcomes.

Conclusions

Endometrial characteristics in recipients prior to and following progesterone were not predictive of pregnancy outcomes.

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Title: Follicular and luteal phase endometrial thickness and echogenic pattern and pregnancy outcome in oocyte donation cycles
Authors: Matthew A. Barker
Lynn M. Boehnlein
Peter Kovacs
Steven R. Lindheim
Publication date: 01-05-2009
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 5/2009
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-009-9312-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Follicular and luteal phase endometrial thickness and echogenic pattern and pregnancy outcome in oocyte donation cycles

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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