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Journal of Assisted Reproduction and Genetics
Published in: Journal of Assisted Reproduction and Genetics 4/2008

01-04-2008 | Assisted Reproduction

Natural IVF cycles may be desirable for women with repeated failures by stimulated IVF cycles

Authors: Toshiki Matsuura, Yuji Takehara, Hirotsune Kaijima, Shokichi Teramoto, Osamu Kato

Published in: Journal of Assisted Reproduction and Genetics | Issue 4/2008

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Abstract

Purpose

Although many reports support stimulated in vitro fertilization, several patients do not respond to it well. Furthermore, stimulated treatment could be associated with reduced ovarian response. We describe three successful cases involving patients of advanced age from whom dominant follicles were retrieved during the natural cycle.

Materials and methods

All patients had failed to bear children through stimulated in vitro fertilization. In case 1, a follicle was retrieved after a gonadotropin-releasing hormone agonist was used to induce luteinizing hormone surge. In cases 2 and 3, pregnancy was achieved via completely natural cycles.

Results

One embryo was transferred every 16 cycles. Ongoing pregnancy—defined as pregnancy progressing beyond gestation week 9—was established in three cycles. The patients successfully delivered and had uneventful neonatal courses.

Conclusion

Mature oocyte retrieval followed by natural rather than stimulated in vitro fertilization might be a potential treatment for patients of advanced age when stimulated in vitro fertilization has been repeatedly unsuccessful.
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Metadata
Title
Natural IVF cycles may be desirable for women with repeated failures by stimulated IVF cycles
Authors
Toshiki Matsuura
Yuji Takehara
Hirotsune Kaijima
Shokichi Teramoto
Osamu Kato
Publication date
01-04-2008
Publisher
Springer US
Published in
Journal of Assisted Reproduction and Genetics / Issue 4/2008
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI
https://doi.org/10.1007/s10815-008-9204-7

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