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01-01-2021 | Angiography | Original Paper

Impact of sub-foveal choroidal thickness on clinical features and long-term clinical outcomes in polypoidal choroidal vasculopathy

Authors: Ramesh Venkatesh, Santosh Gopi Krishna Gadde, Arpitha Pereira, Vivek Singh, Sajjan Sangai, Akhila Sridharan, Bharathi Bavaharan, Nimesh Jain, Naresh Kumar Yadav

Published in: International Ophthalmology | Issue 1/2021

Abstract

Purpose

To study the clinical features and long-term clinical outcomes in polypoidal choroidal vasculopathy (PCV) in eyes with different sub-foveal choroidal thickness (SFCT).

Methods

In this retrospective, observational comparative study, treatment-naïve eyes diagnosed with PCV using the ‘EVEREST-2’ study criteria were included. The eyes were divided into three groups of thin, medium and thick choroids, based on the SFCT data of total study eyes. Demographic, clinical, imaging features and treatment outcomes between the 3 groups were compared.

Results

Sixty-three eyes in 63 patients were included. Right eye was involved in 39 (61%) cases and left eye in 24 (39%) cases. Mean age was 68.3 ± 6.82 years (range 54–85 years). Mean SFCT was 274 µm (median = 269 µm), and one standard deviation was 79.2 µm. Totally, 11, 43 and 9 eyes were included in the thin, medium and thick choroid groups, respectively. The mean SFCT was 161 ± 24.1 µm, 275 ± 39.6 µm and 412 ± 26.2 µm in the thin, medium and thick choroid groups, respectively. There was no statistically significant difference in the clinical and imaging features and treatment outcomes between eyes with thin, medium and thick SFCT.

Conclusion

Eyes with PCV can have a choroid of varying thicknesses. Clinical, imaging and treatment responses were similar between the three sub-foveal choroidal thickness groups in this study. In future, more studies are required to evaluate the role of the choroidal thickness and its relationship to treatment in PCV.

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Title: Impact of sub-foveal choroidal thickness on clinical features and long-term clinical outcomes in polypoidal choroidal vasculopathy
Authors: Ramesh Venkatesh
Santosh Gopi Krishna Gadde
Arpitha Pereira
Vivek Singh
Sajjan Sangai
Akhila Sridharan
Bharathi Bavaharan
Nimesh Jain
Naresh Kumar Yadav
Publication date: 01-01-2021
Publisher: Springer Netherlands
Keyword: Angiography
Published in: International Ophthalmology / Issue 1/2021
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-020-01555-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Impact of sub-foveal choroidal thickness on clinical features and long-term clinical outcomes in polypoidal choroidal vasculopathy

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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