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International Ophthalmology

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01-06-2020 | Uveitis | Original Paper

Anterior segment parameters in Behçet’s patients with ocular involvement

Authors: Selma Ozbek-Uzman, Gulten Karatas Sungur, Zuleyha Yalniz-Akkaya, Gozde Orman, Ayse Burcu, Firdevs Ornek

Published in: International Ophthalmology | Issue 6/2020

Abstract

Purpose

To evaluate anterior segment findings in Behçet’s disease patients within the ocular involvement inactive period.

Methods

One hundred twenty patients with Behçet uveitis in the inactive period (Behçet’s disease group) and 121-age and sex matched healthy subjects (control group) were examined. Anterior segment parameters were assessed by Scheimpflug camera.

Results

In Behçet’s disease group, the mean age was 39.89 ± 10.16 years, and 55.8% of patients were male; in the control group, the mean age was 38.69 ± 14.08 years, and 56.2% of control subjects were male. Pachymetric measurements of corneal apex (523.84 ± 30.36 µ vs 540.73 ± 27.85 µ, p < 0.001) thinnest point (518.70 ± 30.75 µ vs 537 ± 28.66 µ, p < 0.001), mean corneal volume (57.90 ± 3.39 mm³ vs 59.57 ± 3.37 mm³, p < 0.001) were significantly lower and anterior elevation [5.0 (1.0–34.0) vs 2.0 (1.0–7.0) diopter(D), p < 0.001], posterior elevation [11.0 (1.0–66.0) vs 4.0 (0–22.0) D, p < 0.001)] and corneal astigmatism [1.1 (0–7.1) vs 0.7 (0.1–5.7) D, p = 0.005] were significantly higher in the Behçet’s disease group than in control group. No significant difference was found in other anterior segment parameters between the Behçet’s disease group and control group. Concurrent keratoconus was detected in two cases (1.7%). A statistically significant correlation was found between the corneal measurements and frequency of uveitis attacks.

Conclusion

The chronic inflammatory process associated with various proinflammatory cytokines, which play a role in the pathogenesis of keratoconus, may also contribute to a decrease in corneal thickness and corneal volume in Behçet’s patients with ocular involvement.

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Title: Anterior segment parameters in Behçet’s patients with ocular involvement
Authors: Selma Ozbek-Uzman
Gulten Karatas Sungur
Zuleyha Yalniz-Akkaya
Gozde Orman
Ayse Burcu
Firdevs Ornek
Publication date: 01-06-2020
Publisher: Springer Netherlands
Keywords: Uveitis
Cytokines
Published in: International Ophthalmology / Issue 6/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-020-01304-9

ACC 2024 Congress

Springer Medicine

Anterior segment parameters in Behçet’s patients with ocular involvement

Abstract

Purpose

Methods

Results

Conclusion

ACC 2024 Congress

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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