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International Ophthalmology
Published in: International Ophthalmology 4/2020

Open Access 01-04-2020 | Original Paper

Clinical characteristics of patients hospitalized for ocular chemical injuries in Shanghai from 2012 to 2017

Authors: Tao Li, Bo Jiang, Xiaodong Zhou

Published in: International Ophthalmology | Issue 4/2020

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Abstract

Purpose

To summarize the clinical characteristics of patients with ocular chemical injuries and evaluate their potential relationship with the visual outcome by analyzing the medical records of these patients from January 1, 2012, to December 31, 2017.

Methods

This is a retrospective case series study. Patient data included age, gender, occupational classification, location of ocular chemical injury, initial and final best-corrected distance visual acuity (BCDVA), intraocular pressure (IOP), nature and chemical phase, distribution and severity of chemical injury, management methods, and complications. All variables were evaluated for their potential relationship with visual outcome.

Results

A total of 160 patients were hospitalized with ocular chemical injuries. Majority of the patients were factory workers and arrived at the consultation room less than 24 h after injury. The most common ocular injury setting, classification of severity, causative chemical, chemical phase, and complications were workplace, grade II, unknown and mixed substance, liquid, and elevated IOP, respectively. The risk factors for poor final BCDVA were identified as older age, poor initial BCDVA, and irrigation 24 h after injury (P < 0.001, P < 0.001, and P = 0.011, respectively).

Conclusions

We elaborate the clinical characteristics and outcomes of patients with ocular chemical injuries in Jinshan District, Shanghai. A comprehensive education program should be established and the use of protective eyewear should be promoted to prevent occupation-related ocular chemical injuries.
Literature
1.
Merle H, Gerard M, Schrage N (2008) Ocular burns. J Fr Ophtalmol 31:723–734CrossRef
2.
Sharma N, Kaur M, Agarwal T et al (2018) Treatment of acute ocular chemical burns. Surv Ophthalmol 63:214–235CrossRef
3.
Singh P, Tyagi M, Kumar Y et al (2013) Ocular chemical injuries and their management. Oman J Ophthalmol 6:83–86CrossRef
4.
Haring RS, Sheffield ID, Channa R et al (2016) Epidemiologic trends of chemical ocular burns in the United States. JAMA Ophthalmol 134:1119–1124CrossRef
5.
Maghsoudi H, Gabraely N (2008) Epidemiology and outcome of 121 cases of chemical burn in East Azarbaijan province, Iran. Injury 39:1042–1046CrossRef
6.
Hong J, Qiu T, Wei A et al (2010) Clinical characteristics and visual outcome of severe ocular chemical injuries in Shanghai. Ophthalmology 117:2268–2272CrossRef
7.
Cabalag MS, Wasiak J, Syed Q et al (2015) Early and late complications of ocular burn injuries. J Plast Reconstr Aesthet Surg 68:356–361CrossRef
8.
Baradaran-Rafii A, Eslani M, Haq Z et al (2017) Current and upcoming therapies for ocular surface chemical injuries. Ocul Surf 15:48–64CrossRef
9.
Ghosh S, Salvador-Culla B, Kotagiri A et al (2019) Acute chemical eye injury and limbal stem cell deficiency-A prospective study in the United Kingdom. Cornea 38:8–12CrossRef
10.
Sher LM, Taylor DM, Robinson J et al (2012) The epidemiology of chemical eye exposures reported to the Victorian Poisons Information Centre. Eur J Emerg Med 19:389–394CrossRef
11.
Wang W, Zhou Y, Zeng J et al (2017) Epidemiology and clinical characteristics of patients hospitalized for ocular trauma in South-Central China. Acta Ophthalmol 95:e503–e510CrossRef
12.
Sahraravand A, Haavisto AK, Holopainen JM et al (2017) Ocular traumas in working age adults in Finland—Helsinki ocular trauma study. Acta Ophthalmol 95:288–294CrossRef
13.
Wong MY, Man RE, Gupta P et al (2018) Prevalence, subtypes, severity and determinants of ocular trauma: the Singapore Chinese eye study. Br J Ophthalmol 102:204–209CrossRef
14.
Bizrah M, Yusuf A, Ahmad S (2019) Adherence to treatment and follow-up in patients with severe chemical eye burns. Ophthalmol Ther 8:251–259CrossRef
15.
Bunker DJ, George RJ, Kleinschmidt A et al (2014) Alkali-related ocular burns: a case series and review. J Burn Care Res 35:261–268CrossRef
16.
Bizrah M, Yusuf A, Ahmad S (2019) An update on chemical eye burns. Eye (Lond) 33:1362–1377CrossRef
17.
Macdonald EC, Cauchi PA, Azuara-Blanco A et al (2009) Surveillance of severe chemical corneal injuries in the UK. Br J Ophthalmol 93:1177–1180CrossRef
18.
Spector J, Fernandez WG (2008) Chemical, thermal, and biological ocular exposures. Emerg Med Clin North Am 26:125–136CrossRef
19.
Paschalis EI, Zhou C, Lei F et al (2017) Mechanisms of retinal damage after ocular alkali burns. Am J Pathol 187:1327–1342CrossRef
20.
Tsai JH, Derby E, Holland EJ et al (2006) Incidence and prevalence of glaucoma in severe ocular surface disease. Cornea 25:530–532CrossRef
21.
Lin MP, Eksioglu U, Mudumbai RC et al (2012) Glaucoma in patients with ocular chemical burns. Am J Ophthalmol 154:481–485CrossRef
22.
Cade F, Grosskreutz CL, Tauber A et al (2011) Glaucoma in eyes with severe chemical burn, before and after keratoprosthesis. Cornea 30:1322–1327CrossRef
23.
Brodovsky SC, McCarty CA, Snibson G et al (2000) Management of alkali burns: an 11-year retrospective review. Ophthalmology 107:1829–1835CrossRef
24.
Wagoner MD (1997) Chemical injuries of the eye: current concepts in pathophysiology and therapy. Surv Ophthalmol 41:275–313CrossRef
25.
Barreiro TP, Santos MS, Vieira AC et al (2014) Comparative study of conjunctival limbal transplantation not associated with the use of amniotic membrane transplantation for treatment of total limbal deficiency secondary to chemical injury. Cornea 33:716–720CrossRef
26.
Sharma N, Singh D, Maharana PK et al (2016) Comparison of amniotic membrane transplantation and umbilical cord serum in acute ocular chemical burns: a randomized controlled trial. Am J Ophthalmol 168:157–163CrossRef
27.
Liang L, Li W, Ling S et al (2009) Amniotic membrane extraction solution for ocular chemical burns. Clin Exp Ophthalmol 37:855–863CrossRef
Metadata
Title
Clinical characteristics of patients hospitalized for ocular chemical injuries in Shanghai from 2012 to 2017
Authors
Tao Li
Bo Jiang
Xiaodong Zhou
Publication date
01-04-2020
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 4/2020
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-019-01263-w

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