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01-12-2019 | Vitrectomy | Original Paper

Perfluoro-n-octane-assisted autologous internal limiting membrane plug for refractory macular hole surgery

Authors: An-Lun Wu, Lan-Hsin Chuang, Kuan-Jen Chen, Ling Yeung, Nan-Kai Wang, Laura Liu, Yih-Shiou Hwang, Wei-Chi Wu, Chi-Chun Lai

Published in: International Ophthalmology | Issue 12/2019

Abstract

Purpose

To evaluate a surgical technique using a perfluoro-n-octane (PFO)-assisted autologous internal limiting membrane (ILM) plug for refractory macular holes (MHs).

Methods

This study was a retrospective, consecutive, interventional case series. Patients with refractory MHs following PFO-assisted autologous ILM plugs were reviewed between October 1, 2017, and February 28, 2018. The anatomical results of MH preoperatively and postoperatively were evaluated by fundus examination and optical coherence tomography (OCT). The best-corrected visual acuities (BCVAs) before and after surgery were compared as the functional outcome.

Results

Six eyes of six consecutive patients with refractory MH were enrolled in this study. Successful MH closure and BCVA improvement after the surgeries were obtained in all eyes. There were four male and two female patients, and the mean age was 63.7 ± 11.1 years. Intraoperatively, the average number of autologous ILM grafts we harvested was 2.2 ± 0.4. The mean follow-up was 6.0 ± 1.7 months. The averaged BCVA before and after the surgery at the last visit improved from 20/356 to 20/153. The ILM graft tissue was still visible, as shown by OCT, in all 6 of 6 (100%) eyes during the follow-up period.

Conclusions

This surgical technique using PFO-assisted autologous ILM plug may provide an option for the treatment of refractory MH.

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Title: Perfluoro-n-octane-assisted autologous internal limiting membrane plug for refractory macular hole surgery
Authors: An-Lun Wu
Lan-Hsin Chuang
Kuan-Jen Chen
Ling Yeung
Nan-Kai Wang
Laura Liu
Yih-Shiou Hwang
Wei-Chi Wu
Chi-Chun Lai
Publication date: 01-12-2019
Publisher: Springer Netherlands
Keywords: Vitrectomy
Peeling
Published in: International Ophthalmology / Issue 12/2019
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-019-01123-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Perfluoro-n-octane-assisted autologous internal limiting membrane plug for refractory macular hole surgery

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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