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01-09-2019 | Original Paper

Normative Pentacam anterior and posterior corneal elevation measurements: effects of age, sex, axial length and white-to-white

Authors: Ignacio Almorín-Fernández-Vigo, Inés Sánchez-Guillén, José I. Fernández-Vigo, Ana Macarro-Merino, Bachar Kudsieh, Cristina Fernández-Vigo, José A. Fernández-Vigo

Published in: International Ophthalmology | Issue 9/2019

Abstract

Purpose

To provide normal corneal elevation data for a large Caucasian population and to determine the impacts on these data of age, sex, axial length (AXL) and horizontal white-to-white (WW).

Setting

Centro Internacional de Oftalmología Avanzada, Madrid, Spain.

Design

Retrospective, cross-sectional, observational.

Methods

In this retrospective, cross-sectional, observational study, anterior and posterior corneal elevations were measured in 789 right eyes of subjects with no ocular disease at the thinnest corneal location in relation to a fixed 8-mm best-fit sphere using the Pentacam, and AXL and WW were measured with the IOLMaster. A multiple linear regression model was used to assess the effects of age, sex, AXL and WW on the elevation data.

Results

Mean subject age was 50.5 ± 15 years (range 17–93 years); 64% were women. Mean anterior and posterior corneal elevations were 1.99 ± 1.75 µm (− 7 to 10 µm) and 7.70 ± 5.7 µm (− 6 to 28 µm). Anterior corneal elevations were higher by 0.165 μm and 0.033 μm for every mm reduction in AXL and every year reduction in age, respectively. Sex and WW were not significant predictors of anterior elevations (R² = 7.7%). Posterior corneal elevation increased by 0.186 μm/year of age, 0.707 μm/mm reduction in WW and 0.819 μm/mm reduction in AXL. This variable was also 0.866 μm greater in men (R² = 34.4%).

Conclusion

Anterior corneal elevations decrease with age and are higher for shorter AXL but are not influenced by sex or WW. Posterior corneal elevations increase with age, decreasing AXL, decreasing WW and are higher in men.

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Title: Normative Pentacam anterior and posterior corneal elevation measurements: effects of age, sex, axial length and white-to-white
Authors: Ignacio Almorín-Fernández-Vigo
Inés Sánchez-Guillén
José I. Fernández-Vigo
Ana Macarro-Merino
Bachar Kudsieh
Cristina Fernández-Vigo
José A. Fernández-Vigo
Publication date: 01-09-2019
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 9/2019
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-018-1028-6

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Normative Pentacam anterior and posterior corneal elevation measurements: effects of age, sex, axial length and white-to-white

Abstract

Purpose

Setting

Design

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Setting

Design

Methods

Results

Conclusion

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