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Published in: International Ophthalmology 8/2019

01-08-2019 | Original Paper

Visual prognosis, clinical features, and predisposing factors in non-HIV patients with cytomegalovirus retinitis

Authors: Nasser Shoeibi, Majid Abrishami, Erfan Mohammad Esmaeil, Seyedeh Maryam Hosseini

Published in: International Ophthalmology | Issue 8/2019

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Abstract

Purpose

To study the characteristics and visual outcome of cytomegalovirus retinitis in patients of a tertiary referral ophthalmology center.

Methods

This retrospective cross-sectional study included 16 patients who presented with CMV retinitis between February 2014 and January 2017. Demographics, clinical signs, course of treatment, and visual and anatomical results were analyzed.

Results

Twenty five eyes of 16 patients were included. Eleven (68.8%) were females. The mean age was 29.37 ± 17.12 (range 11–73) years. Involvement was bilateral in 9 (56.2%) cases. HIV serology was negative in all patients. Best-corrected visual acuity was 0.57 ± 0.55 logarithm of the minimal angle of resolution (LogMAR) at the time of presentation and decreased to 0.69 ± 0.55 LogMAR on final visit (P = 0.332). None of the patients participating in this study was HIV-positive.

Conclusion

CMV retinitis is a devastating complication in immunosuppressed. The visual acuity usually decreases despite aggressive appropriate treatment. This observation supports the increasing incidence of CMV infection in non-HIV patients.
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Metadata
Title
Visual prognosis, clinical features, and predisposing factors in non-HIV patients with cytomegalovirus retinitis
Authors
Nasser Shoeibi
Majid Abrishami
Erfan Mohammad Esmaeil
Seyedeh Maryam Hosseini
Publication date
01-08-2019
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 8/2019
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-018-0991-2

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