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International Ophthalmology

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01-01-2019 | Original Paper

Short-term change in higher-order aberrations after mitomycin-C-augmented trabeculectomy

Authors: Seong Ho Jo, Je Hyun Seo

Published in: International Ophthalmology | Issue 1/2019

Abstract

Purpose

To investigate the changes in ocular higher-order aberrations (HOA) after trabeculectomy using mitomycin-C (MMC).

Methods

We retrospectively reviewed data for 63 eyes from 63 glaucoma patients who had undergone MMC augmented trabeculectomy. We measured intraocular pressure (IOP), refractive errors, anterior chamber depth (ACD), and HOA before surgery and 1, 2, and 4 weeks postoperatively. The patients were divided into two groups on the basis of preoperative lens status: phakic and pseudophakic group. We used a paired t test to compare preoperative and postoperative HOA values. Regression analysis was used to compare higher-order total (HOT) change and factors including ACD and age.

Results

For entire eye aberrations, coma-like and total HOT were significantly increased postoperatively at 1 week (P = 0.029, P = 0.005, respectively), but not after 2 or 4 weeks in the phakic group and were not significant at any time in the pseudophakic group. Corneal HOA were significantly increased postoperatively after 1, 2 weeks, but not after 4 weeks in the phakic group and were not significant in the pseudophakic group. For internal optics aberrations, HOA were significantly increased postoperatively at 1, 2, and 4 weeks in the phakic group, but were not significant at any time in the pseudophakic group. However, HOT aberration change showed no correlation with age, ACD, IOP change in either group.

Conclusion

Following trabeculectomy, HOA changes were significantly increased postoperatively at 1, 2 weeks in the phakic group. Therefore, visual complaint-related HOA changes after trabeculectomy may be more profound in phakic patients.

Quigley HA, Addicks EM, Green WR, Maumenee AE (1981) Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage. Arch Ophthalmol 99(4):635–649PubMedCrossRef

Cairns JE (1968) Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol 66(4):673–679PubMedCrossRef

Wong TT, Mead AL, Khaw PT (2005) Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery. Invest Ophthalmol Vis Sci 46(6):2018–2022. https://doi.org/10.1167/iovs.04-0820 PubMedCrossRef

Lama PJ, Fechtner RD (2003) Antifibrotics and wound healing in glaucoma surgery. Surv Ophthalmol 48(3):314–346. https://doi.org/10.1016/s0039-6257(03)00038-9 PubMedCrossRef

Siriwardena D, Edmunds B, Wormald RP, Khaw PT (2004) National survey of antimetabolite use in glaucoma surgery in the United Kingdom. Br J Ophthalmol 88(7):873–876. https://doi.org/10.1136/bjo.2003.034256 PubMedPubMedCentralCrossRef

Matsuda T, Tanihara H, Hangai M, Chihara E, Honda Y (1996) Surgical results and complications of trabeculectomy with intraoperative application of mitomycin C. Jpn J Ophthalmol 40(4):526–532PubMed

Seah SK, Prata JA Jr, Minckler DS, Baerveldt G, Lee PP, Heuer DK (1995) Hypotony following trabeculectomy. J Glaucoma 4(2):73–79PubMedCrossRef

Kook MS, Kim HB, Lee SU (2001) Short-term effect of mitomycin-C augmented trabeculectomy on axial length and corneal astigmatism. J Cataract Refract Surg 27(4):518–523PubMedCrossRef

Delbeke H, Stalmans I, Vandewalle E, Zeyen T (2015) The effect of trabeculectomy on astigmatism. J Glaucoma. https://doi.org/10.1097/IJG.0000000000000236 CrossRef

10.

Mierdel P, Kaemmerer M, Krinke HE, Seiler T (1999) Effects of photorefractive keratectomy and cataract surgery on ocular optical errors of higher order. Graefes Arch Clin Exp Ophthalmol 237(9):725–729PubMedCrossRef

11.

Oshika T, Klyce SD, Applegate RA, Howland HC, El Danasoury MA (1999) Comparison of corneal wavefront aberrations after photorefractive keratectomy and laser in situ keratomileusis. Am J Ophthalmol 127(1):1–7PubMedCrossRef

12.

Fukuoka S, Amano S, Honda N, Mimura T, Usui T, Araie M (2011) Effect of trabeculectomy on ocular and corneal higher order aberrations. Jpn J Ophthalmol 55(5):460–466. https://doi.org/10.1007/s10384-011-0063-x PubMedCrossRef

13.

Cravy TV (1979) Calculation of the change in corneal astigmatism following cataract extraction. Ophthalmic Surg 10(1):38–49PubMed

14.

Holladay JT, Cravy TV, Koch DD (1992) Calculating the surgically induced refractive change following ocular surgery. J Cataract Refract Surg 18(5):429–443PubMedCrossRef

15.

Kretz FT, Tandogan T, Khoramnia R, Auffarth GU (2015) High order aberration and straylight evaluation after cataract surgery with implantation of an aspheric, aberration correcting monofocal intraocular lens. Int J Ophthalmol 8(4):736–741. https://doi.org/10.3980/j.issn.2222-3959.2015.04.17 PubMedPubMedCentralCrossRef

16.

Namba H, Kawasaki R, Narumi M, Sugano A, Homma K, Nishi K, Murakami T, Kato T, Kayama T, Yamashita H (2015) Ocular higher-order wavefront aberrations in the Japanese adult population: the Yamagata Study (Funagata). Invest Ophthalmol Vis Sci 56(1):90–97. https://doi.org/10.1167/iovs.14-15261 CrossRef

17.

Qu J, Sasaki H, Sakamoto Y, Kawakami Y, Sasaki K, Jonasson F (2010) Higher-order ocular aberrations caused by crystalline lens waterclefts. J Cataract Refract Surg 36(5):799–805. https://doi.org/10.1016/j.jcrs.2009.12.026 PubMedCrossRef

18.

SooHoo JR, Seibold LK, Radcliffe NM, Kahook MY (2014) Minimally invasive glaucoma surgery: current implants and future innovations. Can J Ophthalmol 49(6):528–533. https://doi.org/10.1016/j.jcjo.2014.09.002 PubMedCrossRef

19.

Shaarawy T, Goldberg I, Fechtner R (2015) EX-PRESS glaucoma filtration device: review of clinical experience and comparison with trabeculectomy. Surv Ophthalmol 60(4):327–345. https://doi.org/10.1016/j.survophthal.2015.01.001 PubMedCrossRef

20.

Cunliffe IA, Dapling RB, West J, Longstaff S (1992) A prospective study examining the changes in factors that affect visual acuity following trabeculectomy. Eye (Lond) 6(Pt 6):618–622. https://doi.org/10.1038/eye.1992.133 CrossRef

21.

Rosen WJ, Mannis MJ, Brandt JD (1992) The effect of trabeculectomy on corneal topography. Ophthalmic Surg 23(6):395–398PubMed

22.

Hugkulstone CE (1991) Changes in keratometry following trabeculectomy. Br J Ophthalmol 75(4):217–218PubMedPubMedCentralCrossRef

23.

Cunliffe IA, Dapling RB, West J, Longstaff S (1993) The effect of trabeculectomy on corneal topography. Ophthalmic Surg 24(2):135PubMed

24.

Claridge KG, Galbraith JK, Karmel V, Bates AK (1995) The effect of trabeculectomy on refraction, keratometry and corneal topography. Eye (Lond) 9(Pt 3):292–298. https://doi.org/10.1038/eye.1995.57 CrossRef

25.

Dietze PJ, Oram O, Kohnen T, Feldman RM, Koch DD, Gross RL (1997) Visual function following trabeculectomy: effect on corneal topography and contrast sensitivity. J Glaucoma 6(2):99–103PubMedCrossRef

26.

Kadowaki H, Mizoguchi T, Kuroda S, Terauchi H, Nagata M (2001) Surgically-induced astigmatism following single-site phacotrabeculectomy, phacotrabeculotomy and advanced non-penetrating phacotrabeculectomy. Semin Ophthalmol 16(3):158–161. https://doi.org/10.1076/soph.16.3.158.4196 PubMedCrossRef

27.

Vernon SA, Zambarakji HJ, Potgieter F, Evans J, Chell PB (1999) Topographic and keratometric astigmatism up to 1 year following small flap trabeculectomy (microtrabeculectomy). Br J Ophthalmol 83(7):779–782PubMedPubMedCentralCrossRef

28.

Egrilmez S, Ates H, Nalcaci S, Andac K, Yagci A (2004) Surgically induced corneal refractive change following glaucoma surgery: nonpenetrating trabecular surgeries versus trabeculectomy. J Cataract Refract Surg 30(6):1232–1239. https://doi.org/10.1016/j.jcrs.2003.11.055 PubMedCrossRef

29.

Sugimoto K, Ito K, Esaki K, Miyamura M, Sasoh M, Uji Y (2002) Supraciliochoroidal fluid at an early stage after trabeculectomy. Jpn J Ophthalmol 46(5):548–552PubMedCrossRef

30.

Hiraoka T, Miyata K, Nakamura Y, Miyai T, Ogata M, Okamoto F, Oshika T (2013) Influences of cycloplegia with topical atropine on ocular higher-order aberrations. Ophthalmology 120(1):8–13. https://doi.org/10.1016/j.ophtha.2012.07.057 PubMedCrossRef

Title: Short-term change in higher-order aberrations after mitomycin-C-augmented trabeculectomy
Authors: Seong Ho Jo
Je Hyun Seo
Publication date: 01-01-2019
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 1/2019
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-017-0802-1

At a glance: The STEP trials

Springer Medicine

Short-term change in higher-order aberrations after mitomycin-C-augmented trabeculectomy

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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