Skip to main content
Top
Published in: International Ophthalmology 1/2019

01-01-2019 | Original Paper

Role of trabeculectomy in advanced glaucoma: Whether we stand to consider it a bane or a boon today?

Authors: Harinder Singh Sethi, Mayuresh P. Naik, Komal Saluja

Published in: International Ophthalmology | Issue 1/2019

Login to get access

Abstract

Purpose

To elucidate the role of trabeculectomy in advanced glaucoma.

Materials and methods

Only patients with primary open-angle glaucoma were selected. All patients who had cup–disc ratio of 0.9 or a near-total cupping were given a trial of aggressive maximum medical therapy for IOP control for at least 4 weeks. Target IOP was defined as ≤ 12 mm Hg. Patients who showed progression were included in the study. A total of 10 patients were selected. Trabeculectomy was performed using limbal-based conjunctival flap. Patients were followed up for a period of 2 years for visual acuity, intraocular pressure, visual fields, slit-lamp biomicroscopy and bleb morphology.

Results

Mean preoperative intraocular pressure on five drugs was 21.7 ± 3.8 mm Hg (range 18–27 mm Hg) on maximum medical therapy. Mean post-operative intraocular pressure was 11 ± 1.78 mm Hg (range 9–13 mm Hg) and 11 ± 1.92 mm Hg (range 9–14 mm Hg) at 1 month and 6 months post-operatively, respectively. Post-operatively, the visual acuity remained stable in 17 patients. It dropped by 1 Snellen line in 2 patients and 2 Snellen lines in 1 patient, respectively, over a period of 6 months and later improved to 6/6P following cataract surgery. There was no defined visual field progression in any of the 20 patients.

Conclusion

Besides being a cost-effective alternative to medical management, trabeculectomy not only provides a better IOP control but also has a high safety profile when performed by an experienced surgeon.
Literature
1.
go back to reference George R, Ve RS, Vijaya L (2010) Glaucoma in India: estimated burden of disease. J Glaucoma 19(6):391–397CrossRefPubMed George R, Ve RS, Vijaya L (2010) Glaucoma in India: estimated burden of disease. J Glaucoma 19(6):391–397CrossRefPubMed
3.
go back to reference VanVeldhuisen Paul C, Ederer F et al (2000) The advanced glaucoma intervention study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol 130:429–440CrossRef VanVeldhuisen Paul C, Ederer F et al (2000) The advanced glaucoma intervention study (AGIS): 7. The relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalmol 130:429–440CrossRef
4.
go back to reference Caprioli J, Coleman AL (2008) Intraocular pressure fluctuation a risk factor for visual field progression at low intraocular pressures in the advanced glaucoma intervention study. Ophthalmology 115(1123–1129):e3 Caprioli J, Coleman AL (2008) Intraocular pressure fluctuation a risk factor for visual field progression at low intraocular pressures in the advanced glaucoma intervention study. Ophthalmology 115(1123–1129):e3
5.
go back to reference National Institute for Health and Clinical Excellence (NICE) (2009) Glaucoma: diagnosis and management of chronic open angle glaucoma and ocular hypertension. Clinical Guidelines CG85, UK National Institute for Health and Clinical Excellence (NICE) guidelines. Developed by the National Collaborating Centre for Acute Care National Institute for Health and Clinical Excellence (NICE) (2009) Glaucoma: diagnosis and management of chronic open angle glaucoma and ocular hypertension. Clinical Guidelines CG85, UK National Institute for Health and Clinical Excellence (NICE) guidelines. Developed by the National Collaborating Centre for Acute Care
6.
go back to reference Landers J, Martin K, Sarkies N et al (2012) A 20-year follow-up study of trabeculectomy: risk factors and outcomes. Ophthalmology 119(4):694–702CrossRefPubMed Landers J, Martin K, Sarkies N et al (2012) A 20-year follow-up study of trabeculectomy: risk factors and outcomes. Ophthalmology 119(4):694–702CrossRefPubMed
7.
go back to reference Quigely HA, Borman AT (2006) The number of the people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262–267CrossRef Quigely HA, Borman AT (2006) The number of the people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 90:262–267CrossRef
8.
9.
go back to reference Ramakrishnan R, Nirmalan PK, Krishandas R et al (2003) Glaucoma in a rural population of southern India: the Aravind comprehensive eye survey. Ophthalmology 110:1484–1490CrossRefPubMed Ramakrishnan R, Nirmalan PK, Krishandas R et al (2003) Glaucoma in a rural population of southern India: the Aravind comprehensive eye survey. Ophthalmology 110:1484–1490CrossRefPubMed
10.
go back to reference Hodapp E, Parrish RK II, Anderson DR (1993) Clinical decisions in glaucoma. Mosby, St. Louis Hodapp E, Parrish RK II, Anderson DR (1993) Clinical decisions in glaucoma. Mosby, St. Louis
11.
go back to reference Jones E, Clarke J, Khaw PT (2005) Recent advances in trabeculectomy technique. Curr Opin Ophthalmol 16:107–113CrossRefPubMed Jones E, Clarke J, Khaw PT (2005) Recent advances in trabeculectomy technique. Curr Opin Ophthalmol 16:107–113CrossRefPubMed
12.
go back to reference Francis BA, Singh K, Lin SC et al (2011) Novel glaucoma procedures: a report by the American Academy of Ophthalmology. Ophthalmology 118(7):1466–1480CrossRefPubMed Francis BA, Singh K, Lin SC et al (2011) Novel glaucoma procedures: a report by the American Academy of Ophthalmology. Ophthalmology 118(7):1466–1480CrossRefPubMed
13.
go back to reference Souza C, Tran DH, Loman J, Law SK, Coleman AL, Caprioli J (2007) Long-term outcomes of Ahmed glaucoma valve implantation in refractory glaucomas. Am J Ophthalmol 144:893–900CrossRefPubMed Souza C, Tran DH, Loman J, Law SK, Coleman AL, Caprioli J (2007) Long-term outcomes of Ahmed glaucoma valve implantation in refractory glaucomas. Am J Ophthalmol 144:893–900CrossRefPubMed
15.
go back to reference Moster MR, Moster ML (2005) Wipe-out: a complication of glaucoma surgery or just a blast from the past? Am J Ophthalmol 140:705–706CrossRefPubMed Moster MR, Moster ML (2005) Wipe-out: a complication of glaucoma surgery or just a blast from the past? Am J Ophthalmol 140:705–706CrossRefPubMed
Metadata
Title
Role of trabeculectomy in advanced glaucoma: Whether we stand to consider it a bane or a boon today?
Authors
Harinder Singh Sethi
Mayuresh P. Naik
Komal Saluja
Publication date
01-01-2019
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 1/2019
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-017-0797-7

Other articles of this Issue 1/2019

International Ophthalmology 1/2019 Go to the issue