Top

International Ophthalmology

Published in:

01-10-2018 | Case Report

Reperfusion of the choriocapillaris observed using optical coherence tomography angiography in hypertensive choroidopathy

Authors: Miwa Saito, Akihiro Ishibazawa, Reiko Kinouchi, Akitoshi Yoshida

Published in: International Ophthalmology | Issue 5/2018

Abstract

Purpose

Optical coherence tomography angiography (OCTA) can visualize the vascular status of the choriocapillaris noninvasively and separately from the other vascular beds. We describe focal ischemia in the choriocapillaris and reperfusion of the area in hypertensive choroidopathy using en-face OCTA.

Case

A 32-year-old woman diagnosed with pregnancy-induced hypertension presented with acute anorthopia in the right eye after delivery via Caesarian section. Fundus examination showed an Elschnig’s spot and serous retinal detachment (SRD) in the inferior perifoveal region. Early-phase fluorescein angiography and indocyanine green angiography images showed focally delayed choroidal perfusion, i.e., regional absence of choroidal flush. OCTA also showed a focal dark area in a slab of the choriocapillaris corresponding to the angiographic observation. After oral antihypertensive treatment, the dark area on the OCTA image of the choriocapillaris resolved over time in association with the resolving SRD.

Conclusion

En-face OCTA is a useful technology to follow noninvasively the circulatory status of the choriocapillaris in hypertensive choroidopathy.

Tso MO, Jampol LM (1982) Pathophysiology of hypertensive retinopathy. Ophthalmology 89:1132–1145CrossRefPubMed

Hayreh SS, Servais GE, Virdi PS (1986) Fundus lesions in malignant hypertension. VI. Hypertensive choroidopathy. Ophthalmology 93:1383–1400CrossRefPubMed

Kishi S, Tso MO, Hayreh SS (1985) Fundus lesions in malignant hypertension. II. A pathologic study of experimental hypertensive optic neuropathy. Arch Ophthalmol 103:1198–1206CrossRefPubMed

Song YS, Kinouchi R, Ishiko S, Fukui K, Yoshida A (2013) Hypertensive choroidopathy with eclampsia viewed on spectral-domain optical coherence tomography. Graefes Arch Clin Exp Ophthalmol 251:2647–2650. doi:10.1007/s00417-013-2462-9 CrossRefPubMed

Dewilde E, Huygens M, Cools G, Van Calster J (2014) Hypertensive choroidopathy in pre-eclampsia: two consecutive cases. Ophthalmic Surg Lasers Imaging Retina 45:343–346. doi:10.3928/23258160-20140617-02 CrossRefPubMed

Wang RK, Jacques SL, Ma Z, Hurst S, Hanson SR, Gruber A (2007) Three dimensional optical angiography. Opt Express 15:4083–4097CrossRefPubMed

Jia Y, Tan O, Tokayer J, Potsaid B, Wang Y, Liu JJ, Kraus MF, Subhash H, Fujimoto JG, Hornegger J, Huang D (2012) Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express 20:4710–4725. doi:10.1364/OE.20.004710 CrossRefPubMedPubMedCentral

Jia Y, Bailey ST, Hwang TS, McClintic SM, Gao SS, Pennesi ME, Flaxel CJ, Lauer AK, Wilson DJ, Hornegger J, Fujimoto JG, Huang D (2015) Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye. Proc Natl Acad Sci USA 112:E2395–E2402. doi:10.1073/pnas.1500185112 CrossRefPubMedPubMedCentral

Ferrara D, Waheed NK, Duker JS (2015) Investigating the choriocapillaris and choroidal vasculature with new optical coherence tomography technologies. Prog Retin Eye Res. doi:10.1016/j.preteyeres.2015.10.002 CrossRefPubMed

10.

Kinouchi R, Nishikawa N, Ishibazawa A, Yoshida A (2016) Vascular rarefaction at the choriocapillaris in acute posterior multifocal placoid pigment epitheliopathy viewed on OCT angiography. Int Ophthalmol. doi:10.1007/s10792-016-0308-2 CrossRefPubMed

11.

(2000) Report of the national high blood pressure education program working group on high blood pressure in pregnancy. Am J Obstet Gynecol 183: S1–S22

12.

Vest AR, Cho LS (2012) Hypertension in pregnancy. Cardiol Clin 30:407–423. doi:10.1016/j.ccl.2012.04.005 CrossRefPubMed

13.

Kawashima M, Nakajima M, Kawamura A (2008) Indocyanine green angiographic findings of hypertensive choroidopathy. Retin Cases Brief Rep 2:154–157. doi:10.1097/ICB.0b013e318030a98d CrossRefPubMed

14.

Spaide RF, Fujimoto JG, Waheed NK (2015) Image artifacts in optical coherence tomography angiography. Retina 35:2163–2180. doi:10.1097/IAE.0000000000000765 CrossRefPubMedPubMedCentral

15.

Lumbroso B, Rispoli M (2015) Fluorescein angiography and optical coherence tomography-angiography: advantages and disadvantages. In: Lumbroso B, Huang D, Jia Y, Fujimoto JG, Rispoli M (eds) Clinical guide to angio-OCT (non invasive dyeless OCT angiography). Jaypee Brothers Medical Publishers, New Delhi, pp 68–70CrossRef

Title: Reperfusion of the choriocapillaris observed using optical coherence tomography angiography in hypertensive choroidopathy
Authors: Miwa Saito
Akihiro Ishibazawa
Reiko Kinouchi
Akitoshi Yoshida
Publication date: 01-10-2018
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 5/2018
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-017-0705-1

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Reperfusion of the choriocapillaris observed using optical coherence tomography angiography in hypertensive choroidopathy

Abstract

Purpose

Case

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Case

Conclusion

Please log in to get access to this content

Other articles of this Issue 5/2018

Assessment of the safety and efficacy of primary retropupillary fixation of iris-claw intraocular lenses in children with large lens subluxations

The effect of bariatric surgery on the retrobulbar flow hemodynamic parameters in patients with obesity: color Doppler evaluation

Bilateral macular infarction after gemcitabine and carboplatin chemotherapy

Effect of diquafosol tetrasodium 3% on the conjunctival surface and clinical findings after cataract surgery in patients with dry eye

Efficacy and safety of extemporaneously prepared miconazole eye drops in Candida albicans-induced keratomycosis

The evaluation of the risk factors for capsular complications in phacoemulsification