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International Ophthalmology
Published in: International Ophthalmology 4/2017

01-08-2017 | Original Paper

The assessment of peripapillary retinal nerve fiber layer and macular ganglion cell layer changes in obese children: a cross-sectional study using optical coherence tomography

Authors: Omer Karti, Ozlem Nalbantoglu, Saygin Abali, Selma Tunc, Behzat Ozkan

Published in: International Ophthalmology | Issue 4/2017

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Abstract

Purpose

To investigate the relationship between the obesity and optical coherence tomography (OCT) parameters.

Methods

We studied 54 obese and 33 non-obese children and adolescents. Obesity was defined as BMI higher than 95th percentile (BMI SDS > 1.64). OCT measurements were performed in all participants. Anthropometric and biochemical variables were compared with OCT parameters of 174 eyes.

Results

In obese children, in all quadrants retinal nerve fiber layer (RNFL) thicknesses were significantly lower than non-obese children, and also ganglion cell–inner plexiform layer thicknesses in inferior and superiortemporal quadrants were significantly lower in the obese group. BMI SDS, insulin, HOMA-IR and triglyceride levels were negatively correlated with RNFL thickness, significantly (r = −0.386, p < 0.001; r = −0.229, p = 0.002; r = −0.188, p = 0.013; and r = −0.301, p = 0.000; respectively) in all subjects.

Conclusions

Thinning in RNFL was detected in normal-looking discs of obese children, and this thinning negatively correlated with BMI SDS. Further studies including large series are needed to clarify whether obesity has an effect on RNFL thickness.
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Metadata
Title
The assessment of peripapillary retinal nerve fiber layer and macular ganglion cell layer changes in obese children: a cross-sectional study using optical coherence tomography
Authors
Omer Karti
Ozlem Nalbantoglu
Saygin Abali
Selma Tunc
Behzat Ozkan
Publication date
01-08-2017
Publisher
Springer Netherlands
Published in
International Ophthalmology / Issue 4/2017
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-016-0371-8

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