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01-02-2016 | Original Paper

Progression of gyrate atrophy measured with ultra-wide-field imaging

Authors: Guillermo Salcedo-Villanueva, Miguel Paciuc-Beja, Cristina Villanueva-Mendoza, Mariana Harasawa, Jesse M. Smith, Raul Velez-Montoya, Jeffrey L. Olson, Scott C. Oliver, Naresh Mandava, Hugo Quiroz-Mercado

Published in: International Ophthalmology | Issue 1/2016

Abstract

The study aims to determine the progression of gyrate atrophy by measuring the area growth of chorioretinal atrophic lesions using ultra-wide-field images (UWFI). A retrospective, observational, and comparative study was conducted and UWFI (200°) were obtained from two patients with gyrate atrophy at baseline and follow-up. Measurements of atrophy were obtained for three types of lesions: Solitary atrophic lesions (SAL), De novo solitary lesions (DNSL), and peripapillary atrophy (PPA). Comparison of baseline and follow-up was done using t tests. Two patients with gyrate atrophy were included. Patient 1 presented 16 SAL, 5 DNSL, and PPA measured for both eyes (BE). Overall area growth (OAG) for SAL (expressed in decimals) presented a mean of 3.41, σ 3.07. DNSL area for BE presented a mean of 1586.08 P ², σ 1069.55. OAG for PPA presented a mean of 1.21, σ 0.17. Patient 2 presented 5 SAL, no DNSL, and PPA was measured for BE. OAG for SAL presented a mean of 1.58, σ 1.05 (range 1.02–3.47). OAG for PPA presented a mean of 1.05, σ 0.001. Gyrate atrophy progression can be determined by measuring the changes in area using UWFI.

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Title: Progression of gyrate atrophy measured with ultra-wide-field imaging
Authors: Guillermo Salcedo-Villanueva
Miguel Paciuc-Beja
Cristina Villanueva-Mendoza
Mariana Harasawa
Jesse M. Smith
Raul Velez-Montoya
Jeffrey L. Olson
Scott C. Oliver
Naresh Mandava
Hugo Quiroz-Mercado
Publication date: 01-02-2016
Publisher: Springer Netherlands
Published in: International Ophthalmology / Issue 1/2016
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-015-0085-3

At a glance: The STEP trials

Springer Medicine

Progression of gyrate atrophy measured with ultra-wide-field imaging

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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