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01-04-2021 | Colonoscopy | Letter to the Editor

Letter to the Editor-Recent advances in Lynch syndrome

Authors: Pål Møller, Julian Sampson, Mev Dominguez-Valentin, John Burn, Lone Sunde, Gabriela Möslein, Jukka-Pekka Mecklin, Toni Seppälä

Published in: Familial Cancer | Issue 2/2021

Excerpt

In April 2019, Familial Cancer published an article ‘Recent advances in Lynch Syndrome’ by Biller, Syngal and Yurgelun [1]. Unfortunately, their review contained misunderstandings of some of the sources they cite, among which reports from the Prospective Lynch Syndrome Database (PLSD). …

Biller LH, Syngal S, Yurgelun MB (2019) Recent advances in Lynch syndrome. Familial Cancer 18:211. https://doi.org/10.1007/s10689-018-00117-1CrossRefPubMedPubMedCentral

Engel C, Vasen HF, Seppala T et al (2018) No difference in colorectal cancer incidence or stage at detection by colonoscopy among 3 countries with different Lynch syndrome surveillance policies. Gastroenterology. https://doi.org/10.1053/j.gastro.2018.07.030CrossRefPubMed

Møller P, Seppälä T, Bernstein I et al (2017) Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the Prospective Lynch Syndrome Database. Gut 66(3):464–472. https://doi.org/10.1136/gutjnl-2015-309675CrossRefPubMed

Moller P, Seppala T, Bernstein I et al (2017) Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the Prospective Lynch Syndrome Database. Gut 66(9):1657–1664. https://doi.org/10.1136/gutjnl-2016-311403CrossRefPubMed

Møller P, Seppälä TT, Bernstein I et al (2018) Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database. Gut 67(7):1306CrossRefPubMed

Møller P (2020) The prospective Lynch syndrome database reports enable evidence-based personal precision health care. Hered Cancer Clin Pract 8:6. https://doi.org/10.1186/s13053-020-0138-0CrossRef

Seppälä TT, Dominguez-Valentin M, Sampson JR, Møller P (2020) Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD). Fam Cancer. https://doi.org/10.1007/s10689-020-00193-2CrossRefPubMedPubMedCentral

Title: Letter to the Editor-Recent advances in Lynch syndrome
Authors: Pål Møller
Julian Sampson
Mev Dominguez-Valentin
John Burn
Lone Sunde
Gabriela Möslein
Jukka-Pekka Mecklin
Toni Seppälä
Publication date: 01-04-2021
Publisher: Springer Netherlands
Keyword: Colonoscopy
Published in: Familial Cancer / Issue 2/2021
Print ISSN: 1389-9600
Electronic ISSN: 1573-7292
DOI: https://doi.org/10.1007/s10689-020-00200-6

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