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Published in: European Journal of Epidemiology 8/2020

Open Access 01-08-2020 | COVID-19

An epidemiological modelling approach for COVID-19 via data assimilation

Authors: Philip Nadler, Shuo Wang, Rossella Arcucci, Xian Yang, Yike Guo

Published in: European Journal of Epidemiology | Issue 8/2020

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Abstract

The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation which incorporates new data in real-time through variational data assimilation. We analyze and discuss infection rates in the UK, US and Italy. We furthermore develop a custom compartmental SIR model fit to variables related to the available data of the pandemic, named SITR model, which allows for more granular inference on infection numbers. We compare and discuss model results which conducts updates as new observations become available. A hybrid data assimilation approach is applied to make results robust to initial conditions and measurement errors in the data. We use the model to conduct inference on infection numbers as well as parameters such as the disease transmissibility rate or the rate of recovery. The parameterisation of the model is parsimonious and extendable, allowing for the incorporation of additional data and parameters of interest. This allows for scalability and the extension of the model to other locations or the adaption of novel data sources.
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Metadata
Title
An epidemiological modelling approach for COVID-19 via data assimilation
Authors
Philip Nadler
Shuo Wang
Rossella Arcucci
Xian Yang
Yike Guo
Publication date
01-08-2020
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 8/2020
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-020-00676-7

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