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01-02-2021 | COHORT PROFILE

The profile of Rafsanjan Cohort Study

Authors: Hamid Hakimi, Jafar Ahmadi, Alireza Vakilian, Ahmad Jamalizadeh, Zahra Kamyab, Mahya Mehran, Reza Malekzadeh, Hossein Poustchi, Sareh Eghtesad, Farimah Sardari, Mohammadreza Soleimani, Morteza Khademalhosseini, Mohammadreza Abolghasemi, Movahedeh Mohammadi, Tabandeh Sadeghi, Fatemeh Ayoobi, Mitra Abbasi, Maryam Mohamadi, Zahra Jalali, Ali Shamsizadeh, Ali Esmaeili-Nadimi

Published in: European Journal of Epidemiology | Issue 2/2021

Abstract

Owning the largest human-made jungle of pistachio, the second largest copper mine, and being located on the trade route of opium transit, distinguish Rafsanjan from many other cities in Iran. The environmental exposures and lifestyle factors associated with these characteristics of Rafsanjan, have raised concern about possible health outcomes for individuals living in and around this city. Thus, local health authorities initiated the Rafsanjan Cohort Study (RCS), as part of the prospective epidemiological research studies in IrAN (PERSIAN). RCS is a population-based prospective cohort of men and women aged 35–70 years, launched in August 2015. Individuals from diverse socioeconomic levels and lifestyles were recruited from four urban and suburban areas of Rafsanjan (participation rate 67.42%). Questionnaire-based interviews regarding demographics, dietary and environmental exposures, medical and occupational history, as well as anthropometric measurements were completed for all participants. Additionally, bio-specimens (blood, urine, hair, and nail) were collected, and dental and eye examinations were performed. The enrollment phase ended in December 2017, and a 15-year follow-up is planned. A total of 9990 individuals were enrolled in RCS (53.41% females). About 26% of men are pistachio farmers. The baseline prevalence of major non-communicable disease (NCD) risk factors such as cigarette smoking, alcohol consumption and opium use were 25.45%, 10.02%, and 23.81%, respectively. The mean ± SD of other common risk factors are as follows: body mass index (27.83 ± 4.89 mm Hg), systolic blood pressure (107.18 ± 17.56 mm Hg) diastolic blood pressure (71.13 ± 10.83), fasting blood sugar (113.27 ± 39.11 mg/dL) and plasma cholesterol (198.78 ± 41.89 mg/dL). These results indicate a concerning prevalence of NCD risk factors in Rafsanjan city, warranting further detailed investigations, particularly regarding the association of NDC with agricultural/industrial pollutants and drug abuse.

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Title: The profile of Rafsanjan Cohort Study
Authors: Hamid Hakimi
Jafar Ahmadi
Alireza Vakilian
Ahmad Jamalizadeh
Zahra Kamyab
Mahya Mehran
Reza Malekzadeh
Hossein Poustchi
Sareh Eghtesad
Farimah Sardari
Mohammadreza Soleimani
Morteza Khademalhosseini
Mohammadreza Abolghasemi
Movahedeh Mohammadi
Tabandeh Sadeghi
Fatemeh Ayoobi
Mitra Abbasi
Maryam Mohamadi
Zahra Jalali
Ali Shamsizadeh
Ali Esmaeili-Nadimi
Publication date: 01-02-2021
Publisher: Springer Netherlands
Published in: European Journal of Epidemiology / Issue 2/2021
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI: https://doi.org/10.1007/s10654-020-00668-7

At a glance: The STEP trials

Springer Medicine

The profile of Rafsanjan Cohort Study

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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