Skip to main content
Top
Published in: European Journal of Epidemiology 4/2017

01-04-2017 | MORTALITY

Time trends of cause-specific mortality among resettlers in Germany, 1990 through 2009

Authors: Simone Kaucher, Valentina Leier, Andreas Deckert, Bernd Holleczek, Christa Meisinger, Volker Winkler, Heiko Becher

Published in: European Journal of Epidemiology | Issue 4/2017

Login to get access

Abstract

Resettlers (in German: (Spät-)Aussiedler) form one of the biggest migrant groups in Germany. It is known that migrants have different mortality patterns compared to the autochthon population. In this paper, we combined data from three resettler cohorts and examined differences in mortality from non-communicable diseases among resettlers in Germany and the German population. Furthermore, we investigated time trends of cause-specific mortality for 20 years of follow-up and compared it with the German mortality rates. To assess differences in cause-specific mortality between resettlers and the general German population, we calculated standardized mortality ratios (SMRs). To ascertain mortality trends, cause-specific age-standardized mortality rates were calculated and modeled with Poisson regression and fractional polynomials. During the observation period, the study population accumulated almost 800,000 person-years and 5572 deaths were observed. All-cause mortality among resettlers was lower (SMR = 0.91, 95% CI = 0.89–0.94) compared to the general German population, as well as cardiovascular diseases (CVD) mortality (SMR = 0.82, 95% CI = 0.79–0.86). Results for cancer mortality varied considerably by cancer site. Analyses of time trends showed that all-cause and CVD mortality were decreasing over time in resettlers, as well as in the general German population. Lower all-cause mortality among resettlers is mainly explained by lower CVD mortality. Cancer-site specific mortality showed different results. Converging mortality rates may indicate an adaption of lifestyle behavior. However, there are no data on individual risk factors in this study.
Literature
1.
go back to reference Worbs S, Bund E, Kohls M, Babka von Gostomski C. (Spät-) Aussiedler in Deutschland. Eine Analyse aktueller Daten und Forschungsergebnisse. Nürnberg: Bundesamt für Migration und Flüchtlinge; 2013. Worbs S, Bund E, Kohls M, Babka von Gostomski C. (Spät-) Aussiedler in Deutschland. Eine Analyse aktueller Daten und Forschungsergebnisse. Nürnberg: Bundesamt für Migration und Flüchtlinge; 2013.
2.
go back to reference Razum O, Wenner J. Social and health epidemiology of immigrants in Germany: past, present and future. Public Health Rev. 2016;37(1):4.CrossRef Razum O, Wenner J. Social and health epidemiology of immigrants in Germany: past, present and future. Public Health Rev. 2016;37(1):4.CrossRef
3.
go back to reference Bray F, Parkin DM. Descriptive Studies. In: Ahrens W, Pigeot I, editors. Handbook of Epidemiology. 2nd ed. New York: Springer; 2014. p. 187–258. Bray F, Parkin DM. Descriptive Studies. In: Ahrens W, Pigeot I, editors. Handbook of Epidemiology. 2nd ed. New York: Springer; 2014. p. 187–258.
4.
go back to reference Marmot MG, Syme SL. Acculturation and coronary heart disease in Japanese–Americans. Am J Epidemiol. 1976;104(3):225–47.CrossRefPubMed Marmot MG, Syme SL. Acculturation and coronary heart disease in Japanese–Americans. Am J Epidemiol. 1976;104(3):225–47.CrossRefPubMed
5.
go back to reference Razum O, Zeeb H, Gerhardus A. Cardiovascular mortality of Turkish nationals residing in West Germany. Ann Epidemiol. 1998;8(5):334–41.CrossRefPubMed Razum O, Zeeb H, Gerhardus A. Cardiovascular mortality of Turkish nationals residing in West Germany. Ann Epidemiol. 1998;8(5):334–41.CrossRefPubMed
6.
go back to reference Frisbie WP, Cho Y, Hummer RA. Immigration and the health of Asian and Pacific Islander adults in the United States. Am J Epidemiol. 2001;153(4):372–80.CrossRefPubMed Frisbie WP, Cho Y, Hummer RA. Immigration and the health of Asian and Pacific Islander adults in the United States. Am J Epidemiol. 2001;153(4):372–80.CrossRefPubMed
7.
go back to reference Deckert A, Winkler V, Paltiel A, Razum O, Becher H. Time trends in cardiovascular disease mortality in Russia and Germany from 1980 to 2007-are there migration effects? BMC Public Health. 2010;10(1):1.CrossRef Deckert A, Winkler V, Paltiel A, Razum O, Becher H. Time trends in cardiovascular disease mortality in Russia and Germany from 1980 to 2007-are there migration effects? BMC Public Health. 2010;10(1):1.CrossRef
8.
go back to reference Winkler V, Ott JJ, Holleczek B, Stegmaier C, Becher H. Cancer profile of migrants from the Former Soviet Union in Germany: incidence and mortality. Cancer Causes Control. 2009;20(10):1873–9.CrossRefPubMed Winkler V, Ott JJ, Holleczek B, Stegmaier C, Becher H. Cancer profile of migrants from the Former Soviet Union in Germany: incidence and mortality. Cancer Causes Control. 2009;20(10):1873–9.CrossRefPubMed
9.
go back to reference Kyobutungi C, Ronellenfitsch U, Razum O, Becher H. Mortality from external causes among ethnic German immigrants from former Soviet Union countries, in Germany. Eur J Public Health. 2006;16(4):376–82.CrossRefPubMed Kyobutungi C, Ronellenfitsch U, Razum O, Becher H. Mortality from external causes among ethnic German immigrants from former Soviet Union countries, in Germany. Eur J Public Health. 2006;16(4):376–82.CrossRefPubMed
10.
go back to reference Volodina A, Bertsche T, Kostev K, Winkler V, Haefeli WE, Becher H. Drug utilization patterns and reported health status in ethnic German migrants (Aussiedler) in Germany: a cross-sectional study. BMC Public Health. 2011;11(1):1.CrossRef Volodina A, Bertsche T, Kostev K, Winkler V, Haefeli WE, Becher H. Drug utilization patterns and reported health status in ethnic German migrants (Aussiedler) in Germany: a cross-sectional study. BMC Public Health. 2011;11(1):1.CrossRef
11.
go back to reference Ronellenfitsch U, Kyobutungi C, Becher H, Razum O. All-cause and cardiovascular mortality among ethnic German immigrants from the Former Soviet Union: a cohort study. BMC Public Health. 2006;6(1):1.CrossRef Ronellenfitsch U, Kyobutungi C, Becher H, Razum O. All-cause and cardiovascular mortality among ethnic German immigrants from the Former Soviet Union: a cohort study. BMC Public Health. 2006;6(1):1.CrossRef
12.
go back to reference Becher H, Razum O, Kyobutungi C, Laki J, Ott JJ, Ronellenfitsch U, et al. Mortalität von Aussiedlern aus der ehemaligen Sowjetunion. Deutsches Aerzteblatt. 2007;104(23):1655–61. Becher H, Razum O, Kyobutungi C, Laki J, Ott JJ, Ronellenfitsch U, et al. Mortalität von Aussiedlern aus der ehemaligen Sowjetunion. Deutsches Aerzteblatt. 2007;104(23):1655–61.
13.
go back to reference Deckert A, Winkler V, Meisinger C, Heier M, Becher H. Myocardial infarction incidence and ischemic heart disease mortality: overall and trend results in repatriates, Germany. Eur J Public Health. 2014;24(1):127–33.CrossRefPubMed Deckert A, Winkler V, Meisinger C, Heier M, Becher H. Myocardial infarction incidence and ischemic heart disease mortality: overall and trend results in repatriates, Germany. Eur J Public Health. 2014;24(1):127–33.CrossRefPubMed
14.
go back to reference Nichols M, Townsend N, Scarborough P, Rayner M. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013;34(39):3028–34.CrossRefPubMed Nichols M, Townsend N, Scarborough P, Rayner M. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013;34(39):3028–34.CrossRefPubMed
15.
go back to reference Ronellenfitsch U, Kyobutungi C, Becher H, Razum O. Large-scale, population-based epidemiological studies with record linkage can be done in Germany. Eur J Epidemiol. 2004;19(12):1073–4.CrossRefPubMed Ronellenfitsch U, Kyobutungi C, Becher H, Razum O. Large-scale, population-based epidemiological studies with record linkage can be done in Germany. Eur J Epidemiol. 2004;19(12):1073–4.CrossRefPubMed
16.
go back to reference Hammer GP. Makros zur Berechnung von Personenjahren in epidemiologischen Studien. In: Proceedings der 15 Konferenz der SAS-Anwender in Forschung und Entwicklung. 2011; 223–232. Hammer GP. Makros zur Berechnung von Personenjahren in epidemiologischen Studien. In: Proceedings der 15 Konferenz der SAS-Anwender in Forschung und Entwicklung. 2011; 223–232.
17.
go back to reference Greenland S, Rothman KJ. Introduction to Stratified Analysis. In: Rothman KJ, Greenland S, Lash TL, editors. Modern Epidemiology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2008. p. 258–82. Greenland S, Rothman KJ. Introduction to Stratified Analysis. In: Rothman KJ, Greenland S, Lash TL, editors. Modern Epidemiology. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2008. p. 258–82.
19.
go back to reference Gaber E, Wildner M. Themenheft 52 “Sterblichkeit, Todesursachen und regionale Unterschiede”. 2011. Gaber E, Wildner M. Themenheft 52 “Sterblichkeit, Todesursachen und regionale Unterschiede”. 2011.
20.
go back to reference Rittgen W, Becker N. SMR Analysis of Historical Follow-Up Studies with Missing Death Certificates. Biometrics. 2000;56(4):1164–9.CrossRefPubMed Rittgen W, Becker N. SMR Analysis of Historical Follow-Up Studies with Missing Death Certificates. Biometrics. 2000;56(4):1164–9.CrossRefPubMed
21.
go back to reference Pace M, Lanzieri G, Glickman M, Zupanič T. Revision of the European Standard Population: report of Eurostat’s task force. Publications Office of the European Union; 2013. Pace M, Lanzieri G, Glickman M, Zupanič T. Revision of the European Standard Population: report of Eurostat’s task force. Publications Office of the European Union; 2013.
22.
go back to reference Sauerbrei W, Royston P. Building multivariable prognostic and diagnostic models: transformation of the predictors by using fractional polynomials. J R Stat Soc Ser A (Statistics in Society). 1999;162(1):71–94.CrossRef Sauerbrei W, Royston P. Building multivariable prognostic and diagnostic models: transformation of the predictors by using fractional polynomials. J R Stat Soc Ser A (Statistics in Society). 1999;162(1):71–94.CrossRef
23.
go back to reference Krieger V, Kampen H, Paulsen N, Kopp L, Schleicher J, Kampen J. Deutsche aus Russland gestern und heute: Volk auf dem Weg. Landsmannschaft der Deutschen aus Russland eV.; 2006. Krieger V, Kampen H, Paulsen N, Kopp L, Schleicher J, Kampen J. Deutsche aus Russland gestern und heute: Volk auf dem Weg. Landsmannschaft der Deutschen aus Russland eV.; 2006.
24.
go back to reference Razum O, Geiger I, Zeeb H, Ronellenfitsch U. Gesundheitsversorgung von Migranten. Dtsch Arztebl. 2004;101(43):43. Razum O, Geiger I, Zeeb H, Ronellenfitsch U. Gesundheitsversorgung von Migranten. Dtsch Arztebl. 2004;101(43):43.
25.
go back to reference Reiss K, Spallek J, Razum O. ‘Imported risk’or’health transition’? Smoking prevalence among ethnic German immigrants from the Former Soviet Union by duration of stay in Germany-analysis of microcensus data. Int J Equity Health. 2010;9(1):15.CrossRefPubMedPubMedCentral Reiss K, Spallek J, Razum O. ‘Imported risk’or’health transition’? Smoking prevalence among ethnic German immigrants from the Former Soviet Union by duration of stay in Germany-analysis of microcensus data. Int J Equity Health. 2010;9(1):15.CrossRefPubMedPubMedCentral
26.
go back to reference Antecol H, Bedard K. Unhealthy assimilation: why do immigrants converge to American health status levels? Demography. 2006;43(2):337–60.CrossRefPubMed Antecol H, Bedard K. Unhealthy assimilation: why do immigrants converge to American health status levels? Demography. 2006;43(2):337–60.CrossRefPubMed
27.
go back to reference Turra CM, Elo IT. The impact of salmon bias on the Hispanic mortality advantage: new evidence from social security data. Popul Res Policy Rev. 2008;27(5):515–30.CrossRefPubMedPubMedCentral Turra CM, Elo IT. The impact of salmon bias on the Hispanic mortality advantage: new evidence from social security data. Popul Res Policy Rev. 2008;27(5):515–30.CrossRefPubMedPubMedCentral
29.
go back to reference Kibele EU. Appendices of Regional mortality differences in Germany. In: Kibele EU, editor. Regional mortality differences in Germany. Springer Science & Business Media; 2012. p. 217-71. Kibele EU. Appendices of Regional mortality differences in Germany. In: Kibele EU, editor. Regional mortality differences in Germany. Springer Science & Business Media; 2012. p. 217-71.
30.
go back to reference Statistische Ämter des Bundes und der Länder. Zensus 2011—Methoden und Verfahren. Wiesbaden: Statistisches Bundesamt; 2015. Statistische Ämter des Bundes und der Länder. Zensus 2011—Methoden und Verfahren. Wiesbaden: Statistisches Bundesamt; 2015.
31.
go back to reference Bundesamt für Migration und Flüchtlinge. Migrationsbericht des Bundesamtes für Migration und Flüchtlinge im Auftrag der Bundesregierung. 2016. Bundesamt für Migration und Flüchtlinge. Migrationsbericht des Bundesamtes für Migration und Flüchtlinge im Auftrag der Bundesregierung. 2016.
32.
go back to reference Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2016:ehw106. Piepoli MF, Hoes AW, Agewall S, Albus C, Brotons C, Catapano AL et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J. 2016:ehw106.
33.
go back to reference Kuhrs E, Winkler V, Becher H. Risk factors for cardiovascular and cerebrovascular diseases among ethnic Germans from the former Soviet Union: results of a nested case–control study. BMC Public Health. 2012;12(1):1.CrossRef Kuhrs E, Winkler V, Becher H. Risk factors for cardiovascular and cerebrovascular diseases among ethnic Germans from the former Soviet Union: results of a nested case–control study. BMC Public Health. 2012;12(1):1.CrossRef
34.
go back to reference Ganna A, Magnusson PK, Pedersen NL, de Faire U, Reilly M, Ärnlöv J, et al. Multilocus genetic risk scores for coronary heart disease prediction. Arterioscler Thromb Vasc Biol. 2013;33(9):2267–72.CrossRefPubMed Ganna A, Magnusson PK, Pedersen NL, de Faire U, Reilly M, Ärnlöv J, et al. Multilocus genetic risk scores for coronary heart disease prediction. Arterioscler Thromb Vasc Biol. 2013;33(9):2267–72.CrossRefPubMed
35.
go back to reference Havulinna AS, Kettunen J, Ukkola O, Osmond C, Eriksson JG, Kesäniemi YA, et al. A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32 669 individualsnovelty and significance. Hypertension. 2013;61(5):987–94.CrossRefPubMedPubMedCentral Havulinna AS, Kettunen J, Ukkola O, Osmond C, Eriksson JG, Kesäniemi YA, et al. A blood pressure genetic risk score is a significant predictor of incident cardiovascular events in 32 669 individualsnovelty and significance. Hypertension. 2013;61(5):987–94.CrossRefPubMedPubMedCentral
36.
go back to reference Muka T, Koromani F, Portilla E, O’Connor A, Bramer WM, Troup J, et al. The role of epigenetic modifications in cardiovascular disease: a systematic review. Int J Cardiol. 2016;212:174–83.CrossRefPubMed Muka T, Koromani F, Portilla E, O’Connor A, Bramer WM, Troup J, et al. The role of epigenetic modifications in cardiovascular disease: a systematic review. Int J Cardiol. 2016;212:174–83.CrossRefPubMed
37.
go back to reference Andreassi MG. Metabolic syndrome, diabetes and atherosclerosis: influence of gene–environment interaction. Mutat Res/Fundam Mol Mech Mutagen. 2009;667(1):35–43.CrossRef Andreassi MG. Metabolic syndrome, diabetes and atherosclerosis: influence of gene–environment interaction. Mutat Res/Fundam Mol Mech Mutagen. 2009;667(1):35–43.CrossRef
38.
go back to reference Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108.CrossRefPubMed Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108.CrossRefPubMed
39.
go back to reference World Cancer Research Fund International & American Insitute for Cancer Research. Continuous update project report: diet, nutrition, physical activity, and prostate cancer. 2014. World Cancer Research Fund International & American Insitute for Cancer Research. Continuous update project report: diet, nutrition, physical activity, and prostate cancer. 2014.
40.
go back to reference Agudo A, Bonet C, Travier N, González CA, Vineis P, Bueno-de-Mesquita HB, et al. Impact of cigarette smoking on cancer risk in the European prospective investigation into cancer and nutrition study. J Clin Oncol. 2012;30(36):4550–7.CrossRefPubMed Agudo A, Bonet C, Travier N, González CA, Vineis P, Bueno-de-Mesquita HB, et al. Impact of cigarette smoking on cancer risk in the European prospective investigation into cancer and nutrition study. J Clin Oncol. 2012;30(36):4550–7.CrossRefPubMed
41.
go back to reference Boffetta P, Hashibe M, La VC, Zatonski W, Rehm J. The burden of cancer attributable to alcohol drinking. Int J Cancer. 2006;119(4):884–7.CrossRefPubMed Boffetta P, Hashibe M, La VC, Zatonski W, Rehm J. The burden of cancer attributable to alcohol drinking. Int J Cancer. 2006;119(4):884–7.CrossRefPubMed
43.
go back to reference Hirte L, Nolte E, Bain C, McKee M. Breast cancer mortality in Russia and Ukraine 1963–2002: an age-period-cohort analysis. Int J Epidemiol. 2007;36(4):900–6.CrossRefPubMed Hirte L, Nolte E, Bain C, McKee M. Breast cancer mortality in Russia and Ukraine 1963–2002: an age-period-cohort analysis. Int J Epidemiol. 2007;36(4):900–6.CrossRefPubMed
44.
go back to reference Aparicio ML, Döring A, Mielck A, Holle R. Unterschiede zwischen Aussiedlern und der übrigen deutschen Bevölkerung bezüglich Gesundheit, Gesundheitsversorgung und Gesundheitsverhalten: eine vergleichende Analyse anhand des KORA-Surveys 2000. Sozial-und Präventivmedizin. 2005;50(2):107–18.CrossRefPubMed Aparicio ML, Döring A, Mielck A, Holle R. Unterschiede zwischen Aussiedlern und der übrigen deutschen Bevölkerung bezüglich Gesundheit, Gesundheitsversorgung und Gesundheitsverhalten: eine vergleichende Analyse anhand des KORA-Surveys 2000. Sozial-und Präventivmedizin. 2005;50(2):107–18.CrossRefPubMed
45.
go back to reference Wang F, Meng W, Wang B, Qiao L. Helicobacter pylori-induced gastric inflammation and gastric cancer. Cancer Lett. 2014;345(2):196–202.CrossRefPubMed Wang F, Meng W, Wang B, Qiao L. Helicobacter pylori-induced gastric inflammation and gastric cancer. Cancer Lett. 2014;345(2):196–202.CrossRefPubMed
46.
go back to reference Tsukanov VV, Butorin NN, Maady AS, Shtygasheva OV, Amelchugova OS, Tonkikh JL, et al. Helicobacter pylori infection, intestinal metaplasia, and gastric cancer risk in Eastern Siberia. Helicobacter. 2011;16(2):107–12.CrossRefPubMed Tsukanov VV, Butorin NN, Maady AS, Shtygasheva OV, Amelchugova OS, Tonkikh JL, et al. Helicobacter pylori infection, intestinal metaplasia, and gastric cancer risk in Eastern Siberia. Helicobacter. 2011;16(2):107–12.CrossRefPubMed
47.
go back to reference Jaehn P, Holleczek B, Becher H, Winkler V. Histologic types of gastric cancer among migrants from the former Soviet Union and the general population in Germany: what kind of prevention do we need? Eur J Gastroenterol Hepatol. 2016;28(8):863–70.CrossRefPubMed Jaehn P, Holleczek B, Becher H, Winkler V. Histologic types of gastric cancer among migrants from the former Soviet Union and the general population in Germany: what kind of prevention do we need? Eur J Gastroenterol Hepatol. 2016;28(8):863–70.CrossRefPubMed
48.
go back to reference Plummer M, de Martel C, Vignat J, Ferlay J, Bray F, Franceschi S. Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health. 2016;4(9):e609–16.CrossRefPubMed Plummer M, de Martel C, Vignat J, Ferlay J, Bray F, Franceschi S. Global burden of cancers attributable to infections in 2012: a synthetic analysis. Lancet Glob Health. 2016;4(9):e609–16.CrossRefPubMed
49.
go back to reference Cornberg M, Razavi HA, Alberti A, Bernasconi E, Buti M, Cooper C, et al. A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel. Liver Int. 2011;31(s2):30–60.CrossRefPubMed Cornberg M, Razavi HA, Alberti A, Bernasconi E, Buti M, Cooper C, et al. A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel. Liver Int. 2011;31(s2):30–60.CrossRefPubMed
50.
go back to reference Wichmann H-E, Kaaks R, Hoffmann W, Jöckel K-H, Greiser K, Linseisen J. Die Nationale Kohorte. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz. 2012;55(6–7):781–9.CrossRefPubMed Wichmann H-E, Kaaks R, Hoffmann W, Jöckel K-H, Greiser K, Linseisen J. Die Nationale Kohorte. Bundesgesundheitsblatt-Gesundheitsforschung-Gesundheitsschutz. 2012;55(6–7):781–9.CrossRefPubMed
Metadata
Title
Time trends of cause-specific mortality among resettlers in Germany, 1990 through 2009
Authors
Simone Kaucher
Valentina Leier
Andreas Deckert
Bernd Holleczek
Christa Meisinger
Volker Winkler
Heiko Becher
Publication date
01-04-2017
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 4/2017
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-017-0240-4

Other articles of this Issue 4/2017

European Journal of Epidemiology 4/2017 Go to the issue