Skip to main content
Top
Published in: European Journal of Epidemiology 5/2016

01-05-2016 | NUTRITIONAL EPIDEMIOLOGY

Quantifying the benefits of Mediterranean diet in terms of survival

Authors: Andrea Bellavia, Thanasis G. Tektonidis, Nicola Orsini, Alicja Wolk, Susanna C. Larsson

Published in: European Journal of Epidemiology | Issue 5/2016

Login to get access

Abstract

Beneficial effects of Mediterranean diet (MD) have been consistently documented. However, to fully understand the public health implications of MD adherence, an informative step is to quantify these effects in terms of survival time differences. The aim of this study was to evaluate the impact of MD on survival, presenting results in terms of differences in median age at death. We used data from 71,333 participants from a large population-based cohort of Swedish men and women, followed-up between January 1, 1998, and December 31, 2012. A total score of MD, ranging from 0 to 8, was calculated by including information on vegetables and fruits consumption, legumes and nuts, non-refined/high fiber grains, fermented dairy products, fish, red meat, use of olive oil/rapeseed oil, and moderate alcohol intake. Multivariable-adjusted differences in median age at death were estimated with Laplace regression and presented as a function of the MD score. During 15 years of follow-up we documented 14,697 deaths. We observed a linear dose–response association between the MD score and median age at death, with higher score associated with longer survival. The difference in median age at death between participants with the extreme scores (0 vs 8) of MD was up to 2 years (23 months, 95 % CI: 16–29). In this study we documented that adherence to MD may accrue benefits up to 2 years of longer survival.
Literature
1.
go back to reference Estruch R, Ros E, Salas-Salvadó J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368(14):1279–90.CrossRefPubMed Estruch R, Ros E, Salas-Salvadó J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med. 2013;368(14):1279–90.CrossRefPubMed
2.
go back to reference Sofi F, Abbate R, Gensini GF, et al. Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am J Clin Nutr. 2010;92(5):1189–96.CrossRefPubMed Sofi F, Abbate R, Gensini GF, et al. Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am J Clin Nutr. 2010;92(5):1189–96.CrossRefPubMed
3.
go back to reference Uno H, Claggett B, Tian L, et al. Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. J Clin Oncol. 2014;32(22):2380–5.CrossRefPubMedPubMedCentral Uno H, Claggett B, Tian L, et al. Moving beyond the hazard ratio in quantifying the between-group difference in survival analysis. J Clin Oncol. 2014;32(22):2380–5.CrossRefPubMedPubMedCentral
4.
go back to reference Vandenbroucke JP, Von Elm E, Altman DG, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Ann Intern Med. 2007;147(8):163–94.CrossRef Vandenbroucke JP, Von Elm E, Altman DG, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Ann Intern Med. 2007;147(8):163–94.CrossRef
5.
6.
go back to reference Tektonidis TG, Åkesson A, Gigante B, et al. A Mediterranean diet and risk of myocardial infarction, heart failure and stroke: a population-based cohort study. Atherosclerosis. 2015;243(1):93–8.CrossRefPubMed Tektonidis TG, Åkesson A, Gigante B, et al. A Mediterranean diet and risk of myocardial infarction, heart failure and stroke: a population-based cohort study. Atherosclerosis. 2015;243(1):93–8.CrossRefPubMed
7.
go back to reference Bellavia A, Discacciati A, Bottai M, et al. Using Laplace regression to model and predict percentiles of age at death when age is the primary time scale. Am J Epidemiol. 2015;182(3):271–7.CrossRefPubMed Bellavia A, Discacciati A, Bottai M, et al. Using Laplace regression to model and predict percentiles of age at death when age is the primary time scale. Am J Epidemiol. 2015;182(3):271–7.CrossRefPubMed
Metadata
Title
Quantifying the benefits of Mediterranean diet in terms of survival
Authors
Andrea Bellavia
Thanasis G. Tektonidis
Nicola Orsini
Alicja Wolk
Susanna C. Larsson
Publication date
01-05-2016
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 5/2016
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-016-0127-9

Other articles of this Issue 5/2016

European Journal of Epidemiology 5/2016 Go to the issue