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European Journal of Epidemiology
Published in: European Journal of Epidemiology 12/2015

Open Access 01-12-2015 | STUDY UPDATE

The Rotterdam Scan Study: design update 2016 and main findings

Authors: M. Arfan Ikram, Aad van der Lugt, Wiro J. Niessen, Peter J. Koudstaal, Gabriel P. Krestin, Albert Hofman, Daniel Bos, Meike W. Vernooij

Published in: European Journal of Epidemiology | Issue 12/2015

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Abstract

Imaging plays an essential role in research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to elucidate the causes of neurological disease by performing imaging of the brain in a prospective population-based setting. Initially, in 1995 and 1999, random subsamples of participants from the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. Moreover, we describe the imaging protocol, image post-processing techniques, and the main findings to date. Finally, we provide recommendations for future research, which will also be topics of investigation in the Rotterdam Scan Study.
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Metadata
Title
The Rotterdam Scan Study: design update 2016 and main findings
Authors
M. Arfan Ikram
Aad van der Lugt
Wiro J. Niessen
Peter J. Koudstaal
Gabriel P. Krestin
Albert Hofman
Daniel Bos
Meike W. Vernooij
Publication date
01-12-2015
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 12/2015
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-015-0105-7

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