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European Journal of Epidemiology
Published in: European Journal of Epidemiology 1/2015

Open Access 01-01-2015 | NUTRITIONAL EPIDEMIOLOGY

Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort

Authors: Dagrun Engeset, Tonje Braaten, Birgit Teucher, Tilman Kühn, H. B. Bueno-de-Mesquita, Max Leenders, Antonio Agudo, Manuela M. Bergmann, Elisavet Valanou, Androniki Naska, Antonia Trichopoulou, Timothy J. Key, Francesca L. Crowe, Kim Overvad, Emily Sonestedt, Amalia Mattiello, Petra H. Peeters, Maria Wennberg, Jan Håkan Jansson, Marie-Christine Boutron-Ruault, Laure Dossus, Laureen Dartois, Kuanrong Li, Aurelio Barricarte, Heather Ward, Elio Riboli, Claudia Agnoli, José María Huerta, María-José Sánchez, Rosario Tumino, Jone M. Altzibar, Paolo Vineis, Giovanna Masala, Pietro Ferrari, David C. Muller, Mattias Johansson, M. Luisa Redondo, Anne Tjønneland, Anja Olsen, Karina Standahl Olsen, Magritt Brustad, Guri Skeie, Eiliv Lund

Published in: European Journal of Epidemiology | Issue 1/2015

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Abstract

Fish is a source of important nutrients and may play a role in preventing heart diseases and other health outcomes. However, studies of overall mortality and cause-specific mortality related to fish consumption are inconclusive. We examined the rate of overall mortality, as well as mortality from ischaemic heart disease and cancer in relation to the intake of total fish, lean fish, and fatty fish in a large prospective cohort including ten European countries. More than 500,000 men and women completed a dietary questionnaire in 1992–1999 and were followed up for mortality until the end of 2010. 32,587 persons were reported dead since enrolment. Hazard ratios and their 99 % confidence interval were estimated using Cox proportional hazard regression models. Fish consumption was examined using quintiles based on reported consumption, using moderate fish consumption (third quintile) as reference, and as continuous variables, using increments of 10 g/day. All analyses were adjusted for possible confounders. No association was seen for fish consumption and overall or cause-specific mortality for both the categorical and the continuous analyses, but there seemed to be a U-shaped trend (p < 0.000) with fatty fish consumption and total mortality and with total fish consumption and cancer mortality (p = 0.046).
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Metadata
Title
Fish consumption and mortality in the European Prospective Investigation into Cancer and Nutrition cohort
Authors
Dagrun Engeset
Tonje Braaten
Birgit Teucher
Tilman Kühn
H. B. Bueno-de-Mesquita
Max Leenders
Antonio Agudo
Manuela M. Bergmann
Elisavet Valanou
Androniki Naska
Antonia Trichopoulou
Timothy J. Key
Francesca L. Crowe
Kim Overvad
Emily Sonestedt
Amalia Mattiello
Petra H. Peeters
Maria Wennberg
Jan Håkan Jansson
Marie-Christine Boutron-Ruault
Laure Dossus
Laureen Dartois
Kuanrong Li
Aurelio Barricarte
Heather Ward
Elio Riboli
Claudia Agnoli
José María Huerta
María-José Sánchez
Rosario Tumino
Jone M. Altzibar
Paolo Vineis
Giovanna Masala
Pietro Ferrari
David C. Muller
Mattias Johansson
M. Luisa Redondo
Anne Tjønneland
Anja Olsen
Karina Standahl Olsen
Magritt Brustad
Guri Skeie
Eiliv Lund
Publication date
01-01-2015
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 1/2015
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-014-9966-4

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