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European Journal of Epidemiology
Published in: European Journal of Epidemiology 9/2013

01-09-2013 | Letter to the Editor

Serum C-peptide levels as an independent predictor of diabetes mellitus mortality in non-diabetic individuals

Authors: Jin-Young Min, Kyoung-Bok Min

Published in: European Journal of Epidemiology | Issue 9/2013

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Excerpt

Connecting-peptide (C-peptide), a byproduct of proinsulin, is co-secreted with insulin in equimolar amounts from pancreatic β cells. Insulin is extracted by the liver and has a half-life of 3–5 min, whereas C-peptide is subjected to negligible first-pass metabolism by the liver and has a twofold to fivefold longer half-life than insulin and therefore, serves as a surrogate for endogenous insulin secretion [1]. C-peptide has been considered biologically inert and only clinically useful for identifying type 1 and type 2 diabetes mellitus [1]. …
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Metadata
Title
Serum C-peptide levels as an independent predictor of diabetes mellitus mortality in non-diabetic individuals
Authors
Jin-Young Min
Kyoung-Bok Min
Publication date
01-09-2013
Publisher
Springer Netherlands
Published in
European Journal of Epidemiology / Issue 9/2013
Print ISSN: 0393-2990
Electronic ISSN: 1573-7284
DOI
https://doi.org/10.1007/s10654-013-9836-5

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