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Documenta Ophthalmologica
Published in: Documenta Ophthalmologica 3/2011

01-06-2011 | CASE REPORT

Melanoma-associated retinopathy associated with intranasal melanoma

Authors: Shigeki Machida, Hiroshi Ohguro, Masaru Tateda, Hiroaki Sato, Dajiro Kurosaka

Published in: Documenta Ophthalmologica | Issue 3/2011

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Abstract

Purpose

To present a case of melanoma-associated retinopathy (MAR) associated with an intranasal melanoma.

Case report

A 77-year-old Japanese man visited us complaining of night blindness, blurred vision, and color vision difficulties in both eyes. His best-corrected visual acuity was 0.7 in the right and 1.0 in the left eyes. The rod response of the electroretinogram (ERG) was abolished, and the maximum response had a negative waveform. The a-wave of the single-flash cone response was square shaped, and the b-wave was delayed. The ON-response of the long-flash cone ERG was absent, but the OFF-response was preserved. A severe loss of retinal sensitivity was detected by static perimetry. Positron emission tomography showed no abnormal signs. Six months after the initial examination, an intranasal tumor was detected and surgically removed. The final diagnosis based on histopathology was malignant melanoma.

Conclusion

Our case demonstrates that MAR can be associated with an intranasal mucosal melanoma. Thus, in cases where the primary lesion cannot be identified in patients with MAR-like symptoms and signs, we recommend that preferential sites of mucosal melanomas be examined.
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Metadata
Title
Melanoma-associated retinopathy associated with intranasal melanoma
Authors
Shigeki Machida
Hiroshi Ohguro
Masaru Tateda
Hiroaki Sato
Dajiro Kurosaka
Publication date
01-06-2011
Publisher
Springer-Verlag
Published in
Documenta Ophthalmologica / Issue 3/2011
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI
https://doi.org/10.1007/s10633-011-9272-3

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