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Documenta Ophthalmologica
Published in: Documenta Ophthalmologica 2/2009

01-10-2009 | Case report

Fundus autofluorescence in cone dystrophy

Authors: Nan-Kai Wang, Chai Lin Chou, Luiz H. Lima, Wener Cella, Joaquin Tosi, Lawrence A. Yannuzzi, Stephen H. Tsang

Published in: Documenta Ophthalmologica | Issue 2/2009

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Abstract

Purpose To describe fundus autofluorescence (FAF) finding in a case of cone dystrophy. Methods Interventional case report. Results A 23-year-old woman presented with increasing photophobia and decreasing vision in both eyes for 2 years. Fundus examination showed several drusen-like dots. FAF revealed hyper-autofluorescence in the foveola. Electroretinogram (ERG) demonstrated a pure “cone” dystrophy. Conclusion Hyper-autofluorescence in the foveola is a non-specific manifestation of photoreceptor-retinal pigment epithelium dysfunction. ERG studies are essential for accurate diagnosis.
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Holz FG, Spaide RF, Bird AC (2007) Atlas of fundus autofluorescence imaging, 1st edn. Springer, New York, pp 199–205
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Krill AE, Deutman AF (1972) Dominant macular degenerations. The cone dystrophies. Am J Ophthalmol 73:352–369PubMed
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Deutman AF (1974) Benign concentric annular macular dystrophy. Am J Ophthalmol 78:384–396PubMed
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Robson AG, Michaelides M, Luong VA et al (2008) Functional correlates of fundus autofluorescence abnormalities in patients with RPGR or RIMS1 mutations causing cone or cone rod dystrophy. Br J Ophthalmol 92:95–102. doi:10.​1136/​bjo.​2007.​124008 PubMedCrossRef
Metadata
Title
Fundus autofluorescence in cone dystrophy
Authors
Nan-Kai Wang
Chai Lin Chou
Luiz H. Lima
Wener Cella
Joaquin Tosi
Lawrence A. Yannuzzi
Stephen H. Tsang
Publication date
01-10-2009
Publisher
Springer-Verlag
Published in
Documenta Ophthalmologica / Issue 2/2009
Print ISSN: 0012-4486
Electronic ISSN: 1573-2622
DOI
https://doi.org/10.1007/s10633-009-9172-y

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