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Published in: Clinical & Experimental Metastasis 6-7/2017

01-10-2017 | Research Paper

Neurosurgical management of brain metastases

Authors: Sherise D. Ferguson, Kathryn M. Wagner, Sujit S. Prabhu, Mary F. McAleer, Ian E. McCutcheon, Raymond Sawaya

Published in: Clinical & Experimental Metastasis | Issue 6-7/2017

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Abstract

Brain metastases present a significant public health issue, affecting more than 100,000 patients per year in the U.S. and result in significant morbidity. Brain metastases can occur in a variety of clinical situations ranging from multiple brain metastases with uncontrolled systemic disease to a solitary metastasis in the setting of controlled systemic disease. Additionally, advances in genomics have broadened the opportunities for targeted treatment options and potentially more durable systemic responses. As such, the treatment of brain metastases is now more tailored and multimodal, involving systemic, radiation, and surgical therapies, often in combination. This review discusses the historical and current role of neurosurgical techniques in the treatment of brain metastases.
Literature
1.
go back to reference Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T et al (2008) Cancer statistics, 2008. CA 58(2):71–96PubMed Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T et al (2008) Cancer statistics, 2008. CA 58(2):71–96PubMed
2.
go back to reference Fox BD, Cheung VJ, Patel AJ, Suki D, Rao G (2011) Epidemiology of metastatic brain tumors. Neurosurg Clin N Am 22(1):1–6, vCrossRefPubMed Fox BD, Cheung VJ, Patel AJ, Suki D, Rao G (2011) Epidemiology of metastatic brain tumors. Neurosurg Clin N Am 22(1):1–6, vCrossRefPubMed
3.
4.
go back to reference Brastianos PK, Curry WT, Oh KS (2013) Clinical discussion and review of the management of brain metastases. J Natl Compr Cancer Netw 11(9):1153–1164CrossRef Brastianos PK, Curry WT, Oh KS (2013) Clinical discussion and review of the management of brain metastases. J Natl Compr Cancer Netw 11(9):1153–1164CrossRef
5.
go back to reference Eichler AF, Chung E, Kodack DP, Loeffler JS, Fukumura D, Jain RK (2011) The biology of brain metastases-translation to new therapies. Nat Rev Clin Oncol 8(6):344–356PubMedPubMedCentral Eichler AF, Chung E, Kodack DP, Loeffler JS, Fukumura D, Jain RK (2011) The biology of brain metastases-translation to new therapies. Nat Rev Clin Oncol 8(6):344–356PubMedPubMedCentral
6.
go back to reference Rostami R, Mittal S, Rostami P, Tavassoli F, Jabbari B (2016) Brain metastasis in breast cancer: a comprehensive literature review. J Neurooncol 127(3):407–414CrossRefPubMed Rostami R, Mittal S, Rostami P, Tavassoli F, Jabbari B (2016) Brain metastasis in breast cancer: a comprehensive literature review. J Neurooncol 127(3):407–414CrossRefPubMed
7.
go back to reference Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ et al (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322(8):494–500CrossRefPubMed Patchell RA, Tibbs PA, Walsh JW, Dempsey RJ, Maruyama Y, Kryscio RJ et al (1990) A randomized trial of surgery in the treatment of single metastases to the brain. N Engl J Med 322(8):494–500CrossRefPubMed
8.
go back to reference Vecht CJ, Haaxma-Reiche H, Noordijk EM, Padberg GW, Voormolen JH, Hoekstra FH et al (1993) Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann Neurol 33(6):583–590CrossRefPubMed Vecht CJ, Haaxma-Reiche H, Noordijk EM, Padberg GW, Voormolen JH, Hoekstra FH et al (1993) Treatment of single brain metastasis: radiotherapy alone or combined with neurosurgery? Ann Neurol 33(6):583–590CrossRefPubMed
9.
go back to reference Patchell RA, Tibbs PA, Regine WF, Dempsey RJ, Mohiuddin M, Kryscio RJ et al (1998) Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. JAMA 280(17):1485–1489CrossRefPubMed Patchell RA, Tibbs PA, Regine WF, Dempsey RJ, Mohiuddin M, Kryscio RJ et al (1998) Postoperative radiotherapy in the treatment of single metastases to the brain: a randomized trial. JAMA 280(17):1485–1489CrossRefPubMed
10.
go back to reference Nieder C, Astner ST, Grosu AL, Andratschke NH, Molls M (2007) The role of postoperative radiotherapy after resection of a single brain metastasis. Combined analysis of 643 patients. Strahlenther Onkol 183(10):576–580CrossRefPubMed Nieder C, Astner ST, Grosu AL, Andratschke NH, Molls M (2007) The role of postoperative radiotherapy after resection of a single brain metastasis. Combined analysis of 643 patients. Strahlenther Onkol 183(10):576–580CrossRefPubMed
11.
go back to reference Aoyama H, Tago M, Kato N, Toyoda T, Kenjyo M, Hirota S et al (2007) Neurocognitive function of patients with brain metastasis who received either whole brain radiotherapy plus stereotactic radiosurgery or radiosurgery alone. Int J Radiat Oncol Biol Phys 68(5):1388–1395CrossRefPubMed Aoyama H, Tago M, Kato N, Toyoda T, Kenjyo M, Hirota S et al (2007) Neurocognitive function of patients with brain metastasis who received either whole brain radiotherapy plus stereotactic radiosurgery or radiosurgery alone. Int J Radiat Oncol Biol Phys 68(5):1388–1395CrossRefPubMed
12.
go back to reference Tallet AV, Azria D, Barlesi F, Spano JP, Carpentier AF, Goncalves A et al (2012) Neurocognitive function impairment after whole brain radiotherapy for brain metastases: actual assessment. Radiat Oncol 7(1):77CrossRefPubMedPubMedCentral Tallet AV, Azria D, Barlesi F, Spano JP, Carpentier AF, Goncalves A et al (2012) Neurocognitive function impairment after whole brain radiotherapy for brain metastases: actual assessment. Radiat Oncol 7(1):77CrossRefPubMedPubMedCentral
13.
go back to reference Tendulkar RD, Liu SW, Barnett GH, Vogelbaum MA, Toms SA, Jin T et al (2006) RPA classification has prognostic significance for surgically resected single brain metastasis. Int J Radiat Oncol Biol Phys 66(3):810–817CrossRefPubMed Tendulkar RD, Liu SW, Barnett GH, Vogelbaum MA, Toms SA, Jin T et al (2006) RPA classification has prognostic significance for surgically resected single brain metastasis. Int J Radiat Oncol Biol Phys 66(3):810–817CrossRefPubMed
14.
go back to reference Lee CH, Kim DG, Kim JW, Han JH, Kim YH, Park CK et al (2013) The role of surgical resection in the management of brain metastasis: a 17-year longitudinal study. Acta Neurochir (Wien) 155(3):389–397CrossRef Lee CH, Kim DG, Kim JW, Han JH, Kim YH, Park CK et al (2013) The role of surgical resection in the management of brain metastasis: a 17-year longitudinal study. Acta Neurochir (Wien) 155(3):389–397CrossRef
15.
go back to reference Paek SH, Audu PB, Sperling MR, Cho J, Andrews DW (2005) Reevaluation of surgery for the treatment of brain metastases: review of 208 patients with single or multiple brain metastases treated at one institution with modern neurosurgical techniques. Neurosurgery 56(5):1021–1034PubMed Paek SH, Audu PB, Sperling MR, Cho J, Andrews DW (2005) Reevaluation of surgery for the treatment of brain metastases: review of 208 patients with single or multiple brain metastases treated at one institution with modern neurosurgical techniques. Neurosurgery 56(5):1021–1034PubMed
16.
go back to reference Sperduto CM, Watanabe Y, Mullan J, Hood T, Dyste G, Watts C et al (2008) A validation study of a new prognostic index for patients with brain metastases: the graded prognostic assessment. J Neurosurg 109(Suppl):87–89PubMed Sperduto CM, Watanabe Y, Mullan J, Hood T, Dyste G, Watts C et al (2008) A validation study of a new prognostic index for patients with brain metastases: the graded prognostic assessment. J Neurosurg 109(Suppl):87–89PubMed
17.
go back to reference Sperduto PW, Berkey B, Gaspar LE, Mehta M, Curran W (2008) A new prognostic index and comparison to three other indices for patients with brain metastases: an analysis of 1960 patients in the RTOG database. Int J Radiat Oncol Biol Phys 70(2):510–514CrossRefPubMed Sperduto PW, Berkey B, Gaspar LE, Mehta M, Curran W (2008) A new prognostic index and comparison to three other indices for patients with brain metastases: an analysis of 1960 patients in the RTOG database. Int J Radiat Oncol Biol Phys 70(2):510–514CrossRefPubMed
18.
go back to reference Sperduto PW, Chao ST, Sneed PK, Luo X, Suh J, Roberge D et al (2010) Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4259 patients. Int J Radiat Oncol Biol Phys 77(3):655–61CrossRefPubMed Sperduto PW, Chao ST, Sneed PK, Luo X, Suh J, Roberge D et al (2010) Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4259 patients. Int J Radiat Oncol Biol Phys 77(3):655–61CrossRefPubMed
19.
go back to reference Karnofsky DA, Abelmann WH, Craver LS, Burchenal JH (1948) The use of the nitrogen mustards in the palliative treatment of carcinoma: with particular reference to bronchogenic carcinoma. Cancer 1(4):634–656CrossRef Karnofsky DA, Abelmann WH, Craver LS, Burchenal JH (1948) The use of the nitrogen mustards in the palliative treatment of carcinoma: with particular reference to bronchogenic carcinoma. Cancer 1(4):634–656CrossRef
20.
go back to reference Baumert BG, Rutten I, Dehing-Oberije C, Twijnstra A, Dirx MJ, Debougnoux-Huppertz RM et al (2006) A pathology-based substrate for target definition in radiosurgery of brain metastases. Int J Radiat Oncol Biol Phys 66(1):187–194CrossRefPubMed Baumert BG, Rutten I, Dehing-Oberije C, Twijnstra A, Dirx MJ, Debougnoux-Huppertz RM et al (2006) A pathology-based substrate for target definition in radiosurgery of brain metastases. Int J Radiat Oncol Biol Phys 66(1):187–194CrossRefPubMed
21.
go back to reference Kamp MA, Dibue M, Niemann L, Reichelt DC, Felsberg J, Steiger HJ et al (2012) Proof of principle: supramarginal resection of cerebral metastases in eloquent brain areas. Acta Neurochir (Wien) 154(11):1981–1986CrossRef Kamp MA, Dibue M, Niemann L, Reichelt DC, Felsberg J, Steiger HJ et al (2012) Proof of principle: supramarginal resection of cerebral metastases in eloquent brain areas. Acta Neurochir (Wien) 154(11):1981–1986CrossRef
22.
go back to reference Yoo H, Kim YZ, Nam BH, Shin SH, Yang HS, Lee JS et al (2009) Reduced local recurrence of a single brain metastasis through microscopic total resection. J Neurosurg 110(4):730–736CrossRefPubMed Yoo H, Kim YZ, Nam BH, Shin SH, Yang HS, Lee JS et al (2009) Reduced local recurrence of a single brain metastasis through microscopic total resection. J Neurosurg 110(4):730–736CrossRefPubMed
23.
go back to reference Patel AJ, Suki D, Hatiboglu MA, Rao VY, Fox BD, Sawaya R (2015) Impact of surgical methodology on the complication rate and functional outcome of patients with a single brain metastasis. J Neurosurg 122(5):1132–1143CrossRefPubMed Patel AJ, Suki D, Hatiboglu MA, Rao VY, Fox BD, Sawaya R (2015) Impact of surgical methodology on the complication rate and functional outcome of patients with a single brain metastasis. J Neurosurg 122(5):1132–1143CrossRefPubMed
24.
go back to reference Patel AJ, Suki D, Hatiboglu MA, Abouassi H, Shi W, Wildrick DM et al (2010) Factors influencing the risk of local recurrence after resection of a single brain metastasis. J Neurosurg 113(2):181–189CrossRefPubMed Patel AJ, Suki D, Hatiboglu MA, Abouassi H, Shi W, Wildrick DM et al (2010) Factors influencing the risk of local recurrence after resection of a single brain metastasis. J Neurosurg 113(2):181–189CrossRefPubMed
25.
go back to reference Suki D, Abouassi H, Patel AJ, Sawaya R, Weinberg JS, Groves MD (2008) Comparative risk of leptomeningeal disease after resection or stereotactic radiosurgery for solid tumor metastasis to the posterior fossa. J Neurosurg 108(2):248–257CrossRefPubMed Suki D, Abouassi H, Patel AJ, Sawaya R, Weinberg JS, Groves MD (2008) Comparative risk of leptomeningeal disease after resection or stereotactic radiosurgery for solid tumor metastasis to the posterior fossa. J Neurosurg 108(2):248–257CrossRefPubMed
26.
go back to reference Berghoff AS, Rajky O, Winkler F, Bartsch R, Furtner J, Hainfellner JA et al (2013) Invasion patterns in brain metastases of solid cancers. Neuro Oncol 15(12):1664–1672CrossRefPubMedPubMedCentral Berghoff AS, Rajky O, Winkler F, Bartsch R, Furtner J, Hainfellner JA et al (2013) Invasion patterns in brain metastases of solid cancers. Neuro Oncol 15(12):1664–1672CrossRefPubMedPubMedCentral
27.
go back to reference Siam L, Bleckmann A, Chaung HN, Mohr A, Klemm F, Barrantes-Freer A et al (2015) The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study. Oncotarget 6(30):29254–29267CrossRefPubMedPubMedCentral Siam L, Bleckmann A, Chaung HN, Mohr A, Klemm F, Barrantes-Freer A et al (2015) The metastatic infiltration at the metastasis/brain parenchyma-interface is very heterogeneous and has a significant impact on survival in a prospective study. Oncotarget 6(30):29254–29267CrossRefPubMedPubMedCentral
28.
go back to reference Kamp MA, Rapp M, Slotty PJ, Turowski B, Sadat H, Smuga M et al (2015) Incidence of local in-brain progression after supramarginal resection of cerebral metastases. Acta Neurochir (Wien) 157(6):905–910 (discussion 10–11)CrossRef Kamp MA, Rapp M, Slotty PJ, Turowski B, Sadat H, Smuga M et al (2015) Incidence of local in-brain progression after supramarginal resection of cerebral metastases. Acta Neurochir (Wien) 157(6):905–910 (discussion 10–11)CrossRef
29.
go back to reference Sanmillan JL, Fernandez-Coello A, Fernandez-Conejero I, Plans G, Gabarros A (2016) Functional approach using intraoperative brain mapping and neurophysiological monitoring for the surgical treatment of brain metastases in the central region. J Neurosurg 2016:1–10CrossRef Sanmillan JL, Fernandez-Coello A, Fernandez-Conejero I, Plans G, Gabarros A (2016) Functional approach using intraoperative brain mapping and neurophysiological monitoring for the surgical treatment of brain metastases in the central region. J Neurosurg 2016:1–10CrossRef
30.
go back to reference Mehta MP, Tsao MN, Whelan TJ, Morris DE, Hayman JA, Flickinger JC et al (2005) The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys 63(1):37–46CrossRefPubMed Mehta MP, Tsao MN, Whelan TJ, Morris DE, Hayman JA, Flickinger JC et al (2005) The American Society for Therapeutic Radiology and Oncology (ASTRO) evidence-based review of the role of radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys 63(1):37–46CrossRefPubMed
31.
go back to reference Hasegawa T, Kondziolka D, Flickinger JC, Germanwala A, Lunsford LD (2003) Brain metastases treated with radiosurgery alone: an alternative to whole brain radiotherapy? Neurosurgery 52(6):1318–1326CrossRefPubMed Hasegawa T, Kondziolka D, Flickinger JC, Germanwala A, Lunsford LD (2003) Brain metastases treated with radiosurgery alone: an alternative to whole brain radiotherapy? Neurosurgery 52(6):1318–1326CrossRefPubMed
32.
go back to reference Selek U, Chang EL, Hassenbusch SJ 3rd, Shiu AS, Lang FF, Allen P et al (2004) Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastases. Int J Radiat Oncol Biol Phys 59(4):1097–1106CrossRefPubMed Selek U, Chang EL, Hassenbusch SJ 3rd, Shiu AS, Lang FF, Allen P et al (2004) Stereotactic radiosurgical treatment in 103 patients for 153 cerebral melanoma metastases. Int J Radiat Oncol Biol Phys 59(4):1097–1106CrossRefPubMed
33.
go back to reference Trifiletti DM, Lee CC, Winardi W, Patel NV, Yen CP, Larner JM et al (2015) Brainstem metastases treated with stereotactic radiosurgery: safety, efficacy, and dose response. J Neurooncol 125(2):385–392CrossRefPubMed Trifiletti DM, Lee CC, Winardi W, Patel NV, Yen CP, Larner JM et al (2015) Brainstem metastases treated with stereotactic radiosurgery: safety, efficacy, and dose response. J Neurooncol 125(2):385–392CrossRefPubMed
34.
go back to reference Trifiletti DM, Lee CC, Kano H, Cohen J, Janopaul-Naylor J, Alonso-Basanta M et al (2016) Stereotactic radiosurgery for brainstem metastases: an international cooperative study to define response and toxicity. Int J Radiat Oncol Biol Phys 96(2):280–288CrossRefPubMedPubMedCentral Trifiletti DM, Lee CC, Kano H, Cohen J, Janopaul-Naylor J, Alonso-Basanta M et al (2016) Stereotactic radiosurgery for brainstem metastases: an international cooperative study to define response and toxicity. Int J Radiat Oncol Biol Phys 96(2):280–288CrossRefPubMedPubMedCentral
35.
go back to reference Mathieu D, Kondziolka D, Flickinger JC, Fortin D, Kenny B, Michaud K et al (2008) Tumor bed radiosurgery after resection of cerebral metastases. Neurosurgery 62(4):817–823 (discussion 23–24)CrossRefPubMed Mathieu D, Kondziolka D, Flickinger JC, Fortin D, Kenny B, Michaud K et al (2008) Tumor bed radiosurgery after resection of cerebral metastases. Neurosurgery 62(4):817–823 (discussion 23–24)CrossRefPubMed
36.
go back to reference Jagannathan J, Yen CP, Ray DK, Schlesinger D, Oskouian RJ, Pouratian N et al (2009) Gamma Knife radiosurgery to the surgical cavity following resection of brain metastases. J Neurosurg 111(3):431–438CrossRefPubMed Jagannathan J, Yen CP, Ray DK, Schlesinger D, Oskouian RJ, Pouratian N et al (2009) Gamma Knife radiosurgery to the surgical cavity following resection of brain metastases. J Neurosurg 111(3):431–438CrossRefPubMed
37.
go back to reference Jensen CA, Chan MD, McCoy TP, Bourland JD, deGuzman AF, Ellis TL et al (2011) Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasis. J Neurosurg 114(6):1585–1591CrossRefPubMed Jensen CA, Chan MD, McCoy TP, Bourland JD, deGuzman AF, Ellis TL et al (2011) Cavity-directed radiosurgery as adjuvant therapy after resection of a brain metastasis. J Neurosurg 114(6):1585–1591CrossRefPubMed
38.
go back to reference Choi CY, Chang SD, Gibbs IC, Adler JR, Harsh GRT, Lieberson RE et al (2012) Stereotactic radiosurgery of the postoperative resection cavity for brain metastases: prospective evaluation of target margin on tumor control. Int J Radiat Oncol Biol 84(2):336–42 Choi CY, Chang SD, Gibbs IC, Adler JR, Harsh GRT, Lieberson RE et al (2012) Stereotactic radiosurgery of the postoperative resection cavity for brain metastases: prospective evaluation of target margin on tumor control. Int J Radiat Oncol Biol 84(2):336–42
39.
go back to reference Robbins JR, Ryu S, Kalkanis S, Cogan C, Rock J, Movsas B et al (2012) Radiosurgery to the surgical cavity as adjuvant therapy for resected brain metastasis. Neurosurgery 71(5):937–943CrossRefPubMed Robbins JR, Ryu S, Kalkanis S, Cogan C, Rock J, Movsas B et al (2012) Radiosurgery to the surgical cavity as adjuvant therapy for resected brain metastasis. Neurosurgery 71(5):937–943CrossRefPubMed
40.
go back to reference Atalar B, Modlin LA, Choi CY, Adler JR, Gibbs IC, Chang SD et al (2013) Risk of leptomeningeal disease in patients treated with stereotactic radiosurgery targeting the postoperative resection cavity for brain metastases. Int J Radiat Oncol Biol Phys 87(4):713–718CrossRefPubMed Atalar B, Modlin LA, Choi CY, Adler JR, Gibbs IC, Chang SD et al (2013) Risk of leptomeningeal disease in patients treated with stereotactic radiosurgery targeting the postoperative resection cavity for brain metastases. Int J Radiat Oncol Biol Phys 87(4):713–718CrossRefPubMed
41.
go back to reference Brennan C, Yang TJ, Hilden P, Zhang Z, Chan K, Yamada Y et al (2014) A phase 2 trial of stereotactic radiosurgery boost after surgical resection for brain metastases. Int J Radiat Oncol Biol Phys 88(1):130–136CrossRefPubMed Brennan C, Yang TJ, Hilden P, Zhang Z, Chan K, Yamada Y et al (2014) A phase 2 trial of stereotactic radiosurgery boost after surgical resection for brain metastases. Int J Radiat Oncol Biol Phys 88(1):130–136CrossRefPubMed
42.
go back to reference Ojerholm E, Lee JY, Thawani JP, Miller D, O’Rourke DM, Dorsey JF et al (2014) Stereotactic radiosurgery to the resection bed for intracranial metastases and risk of leptomeningeal carcinomatosis. J Neurosurg 121(Suppl):75–83PubMed Ojerholm E, Lee JY, Thawani JP, Miller D, O’Rourke DM, Dorsey JF et al (2014) Stereotactic radiosurgery to the resection bed for intracranial metastases and risk of leptomeningeal carcinomatosis. J Neurosurg 121(Suppl):75–83PubMed
43.
go back to reference Iorio-Morin C, Masson-Cote L, Ezahr Y, Blanchard J, Ebacher A, Mathieu D (2014) Early Gamma Knife stereotactic radiosurgery to the tumor bed of resected brain metastasis for improved local control. J Neurosurg 121(Suppl):69–74PubMed Iorio-Morin C, Masson-Cote L, Ezahr Y, Blanchard J, Ebacher A, Mathieu D (2014) Early Gamma Knife stereotactic radiosurgery to the tumor bed of resected brain metastasis for improved local control. J Neurosurg 121(Suppl):69–74PubMed
44.
go back to reference Mahajan A, Ahmed S, McAleer MF, Weinberg JS, Li J, Brown P et al (2017) Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial. Lancet Oncol 18(8):1040–1048 Mahajan A, Ahmed S, McAleer MF, Weinberg JS, Li J, Brown P et al (2017) Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial. Lancet Oncol 18(8):1040–1048
45.
go back to reference Asher AL, Burri SH, Wiggins WF, Kelly RP, Boltes MO, Mehrlich M et al (2014) A new treatment paradigm: neoadjuvant radiosurgery before surgical resection of brain metastases with analysis of local tumor recurrence. Int J Radiat Oncol Biol Phys 88(4):899–906CrossRefPubMed Asher AL, Burri SH, Wiggins WF, Kelly RP, Boltes MO, Mehrlich M et al (2014) A new treatment paradigm: neoadjuvant radiosurgery before surgical resection of brain metastases with analysis of local tumor recurrence. Int J Radiat Oncol Biol Phys 88(4):899–906CrossRefPubMed
46.
go back to reference Patel KR, Burri SH, Asher AL, Crocker IR, Fraser RW, Zhang C et al (2016) Comparing preoperative with postoperative stereotactic radiosurgery for resectable brain metastases: a multi-institutional analysis. Neurosurgery 79(2):279–285CrossRefPubMed Patel KR, Burri SH, Asher AL, Crocker IR, Fraser RW, Zhang C et al (2016) Comparing preoperative with postoperative stereotactic radiosurgery for resectable brain metastases: a multi-institutional analysis. Neurosurgery 79(2):279–285CrossRefPubMed
47.
go back to reference Schackert G, Schmiedel K, Lindner C, Leimert M, Kirsch M (2013) Surgery of recurrent brain metastases: retrospective analysis of 67 patients. Acta Neurochir (Wien) 155(10):1823–1832CrossRef Schackert G, Schmiedel K, Lindner C, Leimert M, Kirsch M (2013) Surgery of recurrent brain metastases: retrospective analysis of 67 patients. Acta Neurochir (Wien) 155(10):1823–1832CrossRef
48.
go back to reference Bindal RK, Sawaya R, Leavens ME, Lee JJ (1993) Surgical treatment of multiple brain metastases. J Neurosurg 79(2):210–216CrossRefPubMed Bindal RK, Sawaya R, Leavens ME, Lee JJ (1993) Surgical treatment of multiple brain metastases. J Neurosurg 79(2):210–216CrossRefPubMed
49.
go back to reference Chang EL, Wefel JS, Hess KR, Allen PK, Lang FF, Kornguth DG et al (2009) Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol 10(11):1037–1044CrossRefPubMed Chang EL, Wefel JS, Hess KR, Allen PK, Lang FF, Kornguth DG et al (2009) Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol 10(11):1037–1044CrossRefPubMed
50.
go back to reference Park SH, Hwang SK, Kang DH, Lee SH, Park J, Hwang JH et al (2009) Gamma knife radiosurgery for multiple brain metastases from lung cancer. J Clin Neurosci 16(5):626–629CrossRefPubMed Park SH, Hwang SK, Kang DH, Lee SH, Park J, Hwang JH et al (2009) Gamma knife radiosurgery for multiple brain metastases from lung cancer. J Clin Neurosci 16(5):626–629CrossRefPubMed
51.
go back to reference Serizawa T, Iuchi T, Ono J, Saeki N, Osato K, Odaki M et al (2000) Gamma knife treatment for multiple metastatic brain tumors compared with whole-brain radiation therapy. J Neurosurg 93(Suppl 3):32–36PubMed Serizawa T, Iuchi T, Ono J, Saeki N, Osato K, Odaki M et al (2000) Gamma knife treatment for multiple metastatic brain tumors compared with whole-brain radiation therapy. J Neurosurg 93(Suppl 3):32–36PubMed
52.
go back to reference Raldow AC, Chiang VL, Knisely JP, Yu JB (2013) Survival and intracranial control of patients with 5 or more brain metastases treated with gamma knife stereotactic radiosurgery. Am J Clin Oncol 36(5):486–490CrossRefPubMed Raldow AC, Chiang VL, Knisely JP, Yu JB (2013) Survival and intracranial control of patients with 5 or more brain metastases treated with gamma knife stereotactic radiosurgery. Am J Clin Oncol 36(5):486–490CrossRefPubMed
53.
go back to reference Knoll MA, Oermann EK, Yang AI, Paydar I, Steinberger J, Collins B et al (2016) Survival of patients with multiple intracranial metastases treated with stereotactic radiosurgery: does the number of tumors matter? Am J Clin Oncol Knoll MA, Oermann EK, Yang AI, Paydar I, Steinberger J, Collins B et al (2016) Survival of patients with multiple intracranial metastases treated with stereotactic radiosurgery: does the number of tumors matter? Am J Clin Oncol
54.
go back to reference Papadatos-Pastos D, Banerji U (2011) Revisiting the role of molecular targeted therapies in patients with brain metastases. J Neurooncol 105(3):467–474CrossRefPubMed Papadatos-Pastos D, Banerji U (2011) Revisiting the role of molecular targeted therapies in patients with brain metastases. J Neurooncol 105(3):467–474CrossRefPubMed
55.
go back to reference Caffo M, Barresi V, Caruso G, Cutugno M, La Fata G, Venza M et al (2013) Innovative therapeutic strategies in the treatment of brain metastases. Int J Mol Sci 14(1):2135–2174CrossRefPubMedPubMedCentral Caffo M, Barresi V, Caruso G, Cutugno M, La Fata G, Venza M et al (2013) Innovative therapeutic strategies in the treatment of brain metastases. Int J Mol Sci 14(1):2135–2174CrossRefPubMedPubMedCentral
56.
go back to reference Bindal RK, Sawaya R, Leavens ME, Hess KR, Taylor SH (1995) Reoperation for recurrent metastatic brain tumors. J Neurosurg 83(4):600–604CrossRefPubMed Bindal RK, Sawaya R, Leavens ME, Hess KR, Taylor SH (1995) Reoperation for recurrent metastatic brain tumors. J Neurosurg 83(4):600–604CrossRefPubMed
57.
go back to reference Mensel B, Weigel C, Hosten N (2006) Laser-induced thermotherapy. Recent Results Cancer Res 167:69–75 Mensel B, Weigel C, Hosten N (2006) Laser-induced thermotherapy. Recent Results Cancer Res 167:69–75
58.
59.
go back to reference Lagman C, Chung LK, Pelargos PE, Ung N, Bui TT, Lee SJ et al (2017) Laser neurosurgery: a systematic analysis of magnetic resonance-guided laser interstitial thermal therapies. J Clin Neurosci 36:20–26CrossRefPubMed Lagman C, Chung LK, Pelargos PE, Ung N, Bui TT, Lee SJ et al (2017) Laser neurosurgery: a systematic analysis of magnetic resonance-guided laser interstitial thermal therapies. J Clin Neurosci 36:20–26CrossRefPubMed
60.
go back to reference Rahmathulla G, Recinos PF, Kamian K, Mohammadi AM, Ahluwalia MS, Barnett GH (2014) MRI-guided laser interstitial thermal therapy in neuro-oncology: a review of its current clinical applications. Int Soc Cell 87(2):67–82 Rahmathulla G, Recinos PF, Kamian K, Mohammadi AM, Ahluwalia MS, Barnett GH (2014) MRI-guided laser interstitial thermal therapy in neuro-oncology: a review of its current clinical applications. Int Soc Cell 87(2):67–82
61.
go back to reference Medvid R, Ruiz A, Komotar RJ, Jagid JR, Ivan ME, Quencer RM et al (2015) Current applications of MRI-guided laser interstitial thermal therapy in the treatment of brain neoplasms and epilepsy: a radiologic and neurosurgical overview. Am J Neuroradiol 36(11):1998–2006CrossRefPubMed Medvid R, Ruiz A, Komotar RJ, Jagid JR, Ivan ME, Quencer RM et al (2015) Current applications of MRI-guided laser interstitial thermal therapy in the treatment of brain neoplasms and epilepsy: a radiologic and neurosurgical overview. Am J Neuroradiol 36(11):1998–2006CrossRefPubMed
62.
go back to reference De Poorter J (1995) Noninvasive MRI thermometry with the proton resonance frequency method: study of susceptibility effects. Magnet Reson Med 34(3):359–367CrossRef De Poorter J (1995) Noninvasive MRI thermometry with the proton resonance frequency method: study of susceptibility effects. Magnet Reson Med 34(3):359–367CrossRef
63.
go back to reference Jethwa PR, Barrese JC, Gowda A, Shetty A, Danish SF (2012) Magnetic resonance thermometry-guided laser-induced thermal therapy for intracranial neoplasms: initial experience. Neurosurgery 71(1 Suppl Operative):133–144 (44–45)PubMed Jethwa PR, Barrese JC, Gowda A, Shetty A, Danish SF (2012) Magnetic resonance thermometry-guided laser-induced thermal therapy for intracranial neoplasms: initial experience. Neurosurgery 71(1 Suppl Operative):133–144 (44–45)PubMed
64.
go back to reference Hawasli AH, Kim AH, Dunn GP, Tran DD, Leuthardt EC (2014) Stereotactic laser ablation of high-grade gliomas. Neurosurg Focus 37(6):E1CrossRefPubMed Hawasli AH, Kim AH, Dunn GP, Tran DD, Leuthardt EC (2014) Stereotactic laser ablation of high-grade gliomas. Neurosurg Focus 37(6):E1CrossRefPubMed
65.
go back to reference Voigt JD, Barnett G (2016) The value of using a brain laser interstitial thermal therapy (LITT) system in patients presenting with high grade gliomas where maximal safe resection may not be feasible. Cost Effect Resour Alloc 14:6CrossRef Voigt JD, Barnett G (2016) The value of using a brain laser interstitial thermal therapy (LITT) system in patients presenting with high grade gliomas where maximal safe resection may not be feasible. Cost Effect Resour Alloc 14:6CrossRef
66.
go back to reference Thomas JG, Rao G, Kew Y, Prabhu SS (2016) Laser interstitial thermal therapy for newly diagnosed and recurrent glioblastoma. Neurosurg Focus 41(4):E12CrossRefPubMed Thomas JG, Rao G, Kew Y, Prabhu SS (2016) Laser interstitial thermal therapy for newly diagnosed and recurrent glioblastoma. Neurosurg Focus 41(4):E12CrossRefPubMed
67.
go back to reference Wright J, Chugh J, Wright CH, Alonso F, Hdeib A, Gittleman H et al (2016) Laser interstitial thermal therapy followed by minimal-access transsulcal resection for the treatment of large and difficult to access brain tumors. Neurosurg Focus 41(4):E14CrossRefPubMed Wright J, Chugh J, Wright CH, Alonso F, Hdeib A, Gittleman H et al (2016) Laser interstitial thermal therapy followed by minimal-access transsulcal resection for the treatment of large and difficult to access brain tumors. Neurosurg Focus 41(4):E14CrossRefPubMed
68.
go back to reference Carpentier A, McNichols RJ, Stafford RJ, Itzcovitz J, Guichard JP, Reizine D et al (2008) Real-time magnetic resonance-guided laser thermal therapy for focal metastatic brain tumors. Neurosurgery 63(1 Suppl 1):ONS21–ONS28 (discussion ONS8–ONS9)PubMed Carpentier A, McNichols RJ, Stafford RJ, Itzcovitz J, Guichard JP, Reizine D et al (2008) Real-time magnetic resonance-guided laser thermal therapy for focal metastatic brain tumors. Neurosurgery 63(1 Suppl 1):ONS21–ONS28 (discussion ONS8–ONS9)PubMed
69.
go back to reference Carpentier A, McNichols RJ, Stafford RJ, Guichard JP, Reizine D, Delaloge S et al (2011) Laser thermal therapy: real-time MRI-guided and computer-controlled procedures for metastatic brain tumors. Lasers Surg Med 43(10):943–950CrossRefPubMed Carpentier A, McNichols RJ, Stafford RJ, Guichard JP, Reizine D, Delaloge S et al (2011) Laser thermal therapy: real-time MRI-guided and computer-controlled procedures for metastatic brain tumors. Lasers Surg Med 43(10):943–950CrossRefPubMed
70.
go back to reference Hawasli AH, Ray WZ, Murphy RK, Dacey RG Jr, Leuthardt EC (2012) Magnetic resonance imaging-guided focused laser interstitial thermal therapy for subinsular metastatic adenocarcinoma: technical case report. Neurosurgery 70(2 Suppl Operative):332–337 (discussion 8)PubMed Hawasli AH, Ray WZ, Murphy RK, Dacey RG Jr, Leuthardt EC (2012) Magnetic resonance imaging-guided focused laser interstitial thermal therapy for subinsular metastatic adenocarcinoma: technical case report. Neurosurgery 70(2 Suppl Operative):332–337 (discussion 8)PubMed
71.
go back to reference Rao MS, Hargreaves EL, Khan AJ, Haffty BG, Danish SF (2014) Magnetic resonance-guided laser ablation improves local control for postradiosurgery recurrence and/or radiation necrosis. Neurosurgery 74(6):658–667 (discussion 67)CrossRefPubMed Rao MS, Hargreaves EL, Khan AJ, Haffty BG, Danish SF (2014) Magnetic resonance-guided laser ablation improves local control for postradiosurgery recurrence and/or radiation necrosis. Neurosurgery 74(6):658–667 (discussion 67)CrossRefPubMed
72.
go back to reference Torres-Reveron J, Tomasiewicz HC, Shetty A, Amankulor NM, Chiang VL (2013) Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery. J Neurooncol 113(3):495–503CrossRefPubMed Torres-Reveron J, Tomasiewicz HC, Shetty A, Amankulor NM, Chiang VL (2013) Stereotactic laser induced thermotherapy (LITT): a novel treatment for brain lesions regrowing after radiosurgery. J Neurooncol 113(3):495–503CrossRefPubMed
73.
go back to reference Ali MA, Carroll KT, Rennert RC, Hamelin T, Chang L, Lemkuil BP et al (2016) Stereotactic laser ablation as treatment for brain metastases that recur after stereotactic radiosurgery: a multiinstitutional experience. Neurosurg Focus 41(4):E11CrossRefPubMed Ali MA, Carroll KT, Rennert RC, Hamelin T, Chang L, Lemkuil BP et al (2016) Stereotactic laser ablation as treatment for brain metastases that recur after stereotactic radiosurgery: a multiinstitutional experience. Neurosurg Focus 41(4):E11CrossRefPubMed
74.
go back to reference Rennert RC, Santiago-Dieppa DR, Figueroa J, Sanai N, Carter BS (2016) Future directions of operative neuro-oncology. J Neurooncol 130(2):377–382CrossRefPubMed Rennert RC, Santiago-Dieppa DR, Figueroa J, Sanai N, Carter BS (2016) Future directions of operative neuro-oncology. J Neurooncol 130(2):377–382CrossRefPubMed
75.
go back to reference Sadikov E, Bezjak A, Yi QL, Wells W, Dawson L, Millar BA et al (2007) Value of whole brain re-irradiation for brain metastases–single centre experience. Clin Oncol (R Coll Radiol) 19(7):532–538CrossRef Sadikov E, Bezjak A, Yi QL, Wells W, Dawson L, Millar BA et al (2007) Value of whole brain re-irradiation for brain metastases–single centre experience. Clin Oncol (R Coll Radiol) 19(7):532–538CrossRef
76.
go back to reference Son CH, Jimenez R, Niemierko A, Loeffler JS, Oh KS, Shih HA (2012) Outcomes after whole brain reirradiation in patients with brain metastases. Int J Radiat Oncol Biol Phys 82(2):e167–e172CrossRefPubMed Son CH, Jimenez R, Niemierko A, Loeffler JS, Oh KS, Shih HA (2012) Outcomes after whole brain reirradiation in patients with brain metastases. Int J Radiat Oncol Biol Phys 82(2):e167–e172CrossRefPubMed
77.
go back to reference Ozgen Z, Atasoy BM, Kefeli AU, Seker A, Dane F, Abacioglu U (2013) The benefit of whole brain reirradiation in patients with multiple brain metastases. Radiat Oncol 8:186CrossRefPubMedPubMedCentral Ozgen Z, Atasoy BM, Kefeli AU, Seker A, Dane F, Abacioglu U (2013) The benefit of whole brain reirradiation in patients with multiple brain metastases. Radiat Oncol 8:186CrossRefPubMedPubMedCentral
78.
go back to reference Chao ST, Barnett GH, Vogelbaum MA, Angelov L, Weil RJ, Neyman G et al (2008) Salvage stereotactic radiosurgery effectively treats recurrences from whole-brain radiation therapy. Cancer 113(8):2198–2204CrossRefPubMed Chao ST, Barnett GH, Vogelbaum MA, Angelov L, Weil RJ, Neyman G et al (2008) Salvage stereotactic radiosurgery effectively treats recurrences from whole-brain radiation therapy. Cancer 113(8):2198–2204CrossRefPubMed
79.
go back to reference Caballero JA, Sneed PK, Lamborn KR, Ma L, Denduluri S, Nakamura JL et al (2012) Prognostic factors for survival in patients treated with stereotactic radiosurgery for recurrent brain metastases after prior whole brain radiotherapy. Int J Radiat Oncol Biol Phys 83(1):303–309CrossRefPubMed Caballero JA, Sneed PK, Lamborn KR, Ma L, Denduluri S, Nakamura JL et al (2012) Prognostic factors for survival in patients treated with stereotactic radiosurgery for recurrent brain metastases after prior whole brain radiotherapy. Int J Radiat Oncol Biol Phys 83(1):303–309CrossRefPubMed
80.
go back to reference McKay WH, McTyre ER, Okoukoni C, Alphonse-Sullivan NK, Ruiz J, Munley MT et al (2016) Repeat stereotactic radiosurgery as salvage therapy for locally recurrent brain metastases previously treated with radiosurgery. J Neurosurg 2016:1–9CrossRef McKay WH, McTyre ER, Okoukoni C, Alphonse-Sullivan NK, Ruiz J, Munley MT et al (2016) Repeat stereotactic radiosurgery as salvage therapy for locally recurrent brain metastases previously treated with radiosurgery. J Neurosurg 2016:1–9CrossRef
Metadata
Title
Neurosurgical management of brain metastases
Authors
Sherise D. Ferguson
Kathryn M. Wagner
Sujit S. Prabhu
Mary F. McAleer
Ian E. McCutcheon
Raymond Sawaya
Publication date
01-10-2017
Publisher
Springer Netherlands
Published in
Clinical & Experimental Metastasis / Issue 6-7/2017
Print ISSN: 0262-0898
Electronic ISSN: 1573-7276
DOI
https://doi.org/10.1007/s10585-017-9860-z

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