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The International Journal of Cardiovascular Imaging

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02-12-2022 | Echocardiography | Originalpaper

Transthoracic echocardiographic assessment of cardiac valves in patients with Behçet’s disease

Authors: Jiarong Fu, Jinfeng Liu, Xiaoming Li, Lili Tang, Shan Wu, Huimei Yu, Chun Zhang

Published in: The International Journal of Cardiovascular Imaging | Issue 4/2023

Abstract

The main objectives of the current study are to investigate valvular involvement in patients with cardiac Behçet’s disease (BD) and find out the risk factors of valvular involvement in cardiac BD. We retrospectively assessed the clinical and echocardiographic data in the medical records of 121 patients with BD admitted to Beijing Anzhen Hospital from January 2015 to January 2022. We evaluated the valvular structure and function mainly by echocardiography. A total of 77 BD patients (77/121, 63.64%) had cardiac valvular involvement. Valvular lesions occurred more frequently in males (p = 0.022). Aortic regurgitation (AR) (62/77, 80.52%) was the most common finding and severe AR occupied 80.65% (50/62). The most common manifestations of BD patients with severe AR was aortic valve prolapse (25/50, 50%), followed by echo-free spaces within the aortic annulus (11/50, 22%), vegetation-like lesions (10/50, 20%), and aortic root aneurysm (10/50, 20%). The incidence of paravalvular leaks (PVL) in BD patients was 14.29% (7/49). The diameter of the sinus of Valsalva and proximal ascending aorta, and total cholesterol (TCHO) were the independent risk factors of moderate-severe aortic valvular regurgitation (p < 0.01). Left ventricular end-diastolic dimension (LVEDD), left ventricular ejection fraction (LVEF) and brain natriuretic peptide (BNP) were significantly associated with moderate-severe mitral valvular regurgitation (p < 0.01). The most common valvular abnormality in BD is AR. Echocardiography has great value in the comprehensive evaluation and accurate diagnosis of valvular involvement in BD patients.

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Title: Transthoracic echocardiographic assessment of cardiac valves in patients with Behçet’s disease
Authors: Jiarong Fu
Jinfeng Liu
Xiaoming Li
Lili Tang
Shan Wu
Huimei Yu
Chun Zhang
Publication date: 02-12-2022
Publisher: Springer Netherlands
Keywords: Echocardiography
Echocardiography
Published in: The International Journal of Cardiovascular Imaging / Issue 4/2023
Print ISSN: 1569-5794
Electronic ISSN: 1875-8312
DOI: https://doi.org/10.1007/s10554-022-02769-8

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Transthoracic echocardiographic assessment of cardiac valves in patients with Behçet’s disease

Abstract

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