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Cancer Causes & Control

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01-10-2016 | Original paper

Risk of cancer in Asian Americans: a Kaiser Permanente cohort study

Authors: H. Nicole Tran, Yan Li, Natalia Udaltsova, Mary Anne Armstrong, Gary D. Friedman, Arthur L. Klatsky

Published in: Cancer Causes & Control | Issue 10/2016

Abstract

Purpose

To supplement published cohort data about incident cancer in Asian Americans (Asians) including risk of specific Asian ethnic groups.

Methods

A cohort study in 124,193 persons (13,344 Asians) with baseline examination data in 1978–1985 used Cox proportional hazards models with seven covariates to estimate hazard ratios (HRs) and 95 % confidence intervals (CIs).

Results

Through 2012 cancer was diagnosed in 18,687 persons including 1,522 Asians. Compared to Whites, the HR (CIs) for any cancer in Asians was 0.8 (0.7–0.9, p < 0.001). Lower Asian risk was stronger for men (HR = 0.7, p < 0.001) than for women (HR = 0.9, p = 0.003). Lower Asian vs. White risks with p < 0.05 were found for cancers of the upper airway digestive area, hematologic malignancies, melanoma, and cancers of the prostate, bladder, and brain. Melanoma contributed substantially to lower Asian risk, especially in women. HRs for specific Asian groups versus Whites follow: Chinese = 0.9 (p < 0.001), Japanese = 0.9 (p = 0.01), Filipinos = 0.8 (p < 0.001), South Asians = 0.5 (p < 0.001), and Other Asians = 0.7 (p = 0.006). Both South Asian men and women had lower risk than Whites, and South Asians had lower risk than any other racial/ethnic group.

Conclusions

Asians had lower cancer risk than Whites, due to lower risk of several cancer types. Each Asian ethnic group had lower risk than Whites with South Asians at the lowest risk.

U.S. Census Bureau PD (2015) Annual estimates of the resident population by sex, race alone or in combination, and hispanic origin for the United States, states, and counties: April 1, 2010 to July 1, 2014

Kwong SL, Chen MS, Snipes KP et al (2005) Asian subgroups and cancer incidence and mortality rates in California. Cancer 104:2975–2981. doi:10.1002/cncr.21511 CrossRefPubMedPubMedCentral

McCracken M, Olsen M, Chen MS et al (2007) Cancer incidence, mortality, and associated risk factors among Asian Americans of Chinese, Filipino, Vietnamese, Korean, and Japanese ethnicities. CA Cancer J Clin 57:190–205. doi:10.3322/canjclin.57.4.190 CrossRefPubMed

Bates JH, Hofer BM, Parikh-Patel A (2008) Cervical cancer incidence, mortality, and survival among Asian subgroups in California, 1990–2004. Cancer 113:2955–2963. doi:10.1002/cncr.23752 CrossRefPubMed

Chen MS (2005) Cancer health disparities among Asian Americans: what we do and what we need to do. Cancer 104:2895–2902. doi:10.1002/cncr.21501 CrossRefPubMed

Lauderdale DS, Huo D (2008) Cancer death rates for older Asian-Americans: classification by race versus ethnicity. Cancer Causes Control 19:135–146. doi:10.1007/s10552-007-9079-4 CrossRefPubMed

Miller BA, Chu KC, Hankey BF, Ries L (2008) Cancer incidence and mortality patterns among specific Asian and Pacific Islander populations in the U.S. Cancer Causes Control 19:227–256. doi:10.1007/s10552-007-9088-3 CrossRefPubMed

Huang V, Li W, Tsai J, Begier E (2013) Cancer mortality among Asians and Pacific Islanders in New York City, 2001–2010. J Cancer Epidemiol 2013:986408. doi:10.1155/2013/986408 CrossRefPubMedPubMedCentral

Bradford PT Skin cancer in skin of color. Dermatol Nurs 21:170–7, 206; quiz 178

10.

Meredith I, Sarfati D, Ikeda T, Blakely T (2012) Cancer in Pacific people in New Zealand. Cancer Causes Control 23:1173–1184. doi:10.1007/s10552-012-9986-x CrossRefPubMed

11.

Carreon JD, Morton LM, Devesa SS et al (2008) Incidence of lymphoid neoplasms by subtype among six Asian ethnic groups in the United States, 1996-2004. Cancer Causes Control 19:1171–1181. doi:10.1007/s10552-008-9184-z CrossRefPubMedPubMedCentral

12.

Yang S-M, Li J-Y, Gale RP, Huang X-J (2015) The mystery of chronic lymphocytic leukemia (CLL): why is it absent in Asians and what does this tell us about etiology, pathogenesis and biology? Blood Rev 29:205–213. doi:10.1016/j.blre.2014.12.001 CrossRefPubMed

13.

Gomez SL, Noone AM, Lichtensztajn DY et al (2013) Cancer incidence trends among Asian American populations in the United States, 1990–2008. J Natl Cancer Inst 105:1096–1110. doi:10.1093/jnci/djt157 CrossRefPubMedPubMedCentral

14.

Chang ET, Keegan THM, Gomez SL et al (2007) The burden of liver cancer in Asians and Pacific Islanders in the Greater San Francisco Bay Area, 1990 through 2004. Cancer 109:2100–2108. doi:10.1002/cncr.22642 CrossRefPubMedPubMedCentral

15.

Wong R, Corley DA (2008) Racial and ethnic variations in hepatocellular carcinoma incidence within the United States. Am J Med 121:525–531. doi:10.1016/j.amjmed.2008.03.005 CrossRefPubMed

16.

Park S, Bae J, Nam B-H, Yoo K-Y (2008) Aetiology of cancer in Asia. Asian Pac J Cancer Prev 9:371–380PubMed

17.

Wang JH, Sheppard VB, Schwartz MD et al (2008) Disparities in cervical cancer screening between Asian American and Non-Hispanic white women. Cancer Epidemiol Biomarkers Prev 17:1968–1973. doi:10.1158/1055-9965.EPI-08-0078 CrossRefPubMed

18.

Tran HN, Li Y, Siu S et al (2013) Predictors of lung cancer: noteworthy cell type differences. Perm J 17:23–29. doi:10.7812/TPP/12-104 CrossRefPubMedPubMedCentral

19.

Taylor VM, Nguyen TT, Jackson JC, McPhee SJ (2008) Cervical cancer control research in Vietnamese American communities. Cancer Epidemiol Biomarkers Prev 17:2924–2930. doi:10.1158/1055-9965.EPI-08-0386 CrossRefPubMedPubMedCentral

20.

Klatsky AL, Siegelaub AB, Landy C, Friedman GD (1983) Racial patterns of alcoholic beverage use. Alcohol Clin Exp Res 7:372–377CrossRefPubMed

21.

Krieger N (1992) Overcoming the absence of socioeconomic data in medical records: validation and application of a census-based methodology. Am J Public Health 82:703–710CrossRefPubMedPubMedCentral

22.

Collen MF, Davis LF (1969) The multitest laboratory in health care. J Occup Med 11:355–360PubMed

23.

McCracken M, Olsen M, Chen MS, et al. Cancer incidence, mortality, and associated risk factors among Asian Americans of Chinese, Filipino, Vietnamese, Korean, and Japanese ethnicities. CA Cancer J Clin 57:190–205

24.

Goh L-Y, Leow AHR, Goh K-L (2014) Observations on the epidemiology of gastrointestinal and liver cancers in the Asia-Pacific region. J Dig Dis 15:463–468. doi:10.1111/1751-2980.12164 CrossRefPubMed

25.

Nguyen EV (2003) Cancer in Asian American males: epidemiology, causes, prevention, and early detection. Asian Am Pac Isl J Health 10:86–99PubMed

26.

Choi CE, Sonnenberg A, Turner K, Genta RM (2015) High prevalence of gastric preneoplastic lesions in East Asians and hispanics in the USA. Dig Dis Sci 60:2070–2076. doi:10.1007/s10620-015-3591-2 CrossRefPubMed

27.

Cortes MCC, Yamakawa A, Casingal CR et al (2010) Diversity of the cagA gene of Helicobacter pylori strains from patients with gastroduodenal diseases in the Philippines. FEMS Immunol Med Microbiol 60:90–97. doi:10.1111/j.1574-695X.2010.00722.x CrossRefPubMed

28.

Wrensch M, Minn Y, Chew T et al (2002) Epidemiology of primary brain tumors: current concepts and review of the literature. Neuro Oncol 4:278–299PubMedPubMedCentral

29.

Chen P, Aldape K, Wiencke JK et al (2001) Ethnicity delineates different genetic pathways in malignant glioma. Cancer Res 61:3949–3954PubMed

30.

Mochizuki S, Iwadate Y, Namba H et al (1999) Homozygous deletion of the p16/MTS-1/CDKN2 gene in malignant gliomas is infrequent among Japanese patients. Int J Oncol 15:983–989PubMed

31.

Raymundo EM, Rice KR, Chen Y et al (2011) Prostate cancer in Asian Americans: incidence, management and outcomes in an equal access healthcare system. BJU Int 107:1216–1222. doi:10.1111/j.1464-410X.2010.09685.x CrossRefPubMed

32.

Kimura T (2012) East meets West: ethnic differences in prostate cancer epidemiology between East Asians and Caucasians. Chin J Cancer 31:421–429. doi:10.5732/cjc.011.10324 CrossRefPubMedPubMedCentral

33.

Anton-Culver H, Lee-Feldstein A, Taylor TH (1993) The association of bladder cancer risk with ethnicity, gender, and smoking. Ann Epidemiol 3:429–433CrossRefPubMed

34.

Herrinton LJ, Goldoft M, Schwartz SM, Weiss NS (1996) The incidence of non-Hodgkin’s lymphoma and its histologic subtypes in Asian migrants to the United States and their descendants. Cancer Causes Control 7:224–230CrossRefPubMed

35.

Soerjomataram I, Lortet-Tieulent J, Parkin DM, et al. (2012) Global burden of cancer in 2008: a systematic analysis of disability-adjusted life-years in 12 world regions. Lancet (London, England) 380:1840–50. doi:10.1016/S0140-6736(12)60919-2

36.

Hislop GT, Bajdik CD, Regier MD, Barroetavena MC (2007) Ethnic differences in survival for female cancers of the breast, cervix and colorectum in British Columbia, Canada. Asian Pac J Cancer Prev 8:209–214PubMed

37.

Moore MA, Manan AA, Chow KY et al (2010) Cancer epidemiology and control in peninsular and island South-East Asia—past, present and future. Asian Pac J Cancer Prev 11(Suppl 2):81–98PubMed

38.

Rastogi T, Devesa S, Mangtani P et al (2008) Cancer incidence rates among South Asians in four geographic regions: India, Singapore, UK and US. Int J Epidemiol 37:147–160. doi:10.1093/ije/dym219 CrossRefPubMed

39.

Goggins WB, Wong G (2009) Cancer among Asian Indians/Pakistanis living in the United States: low incidence and generally above average survival. Cancer Causes Control 20:635–643. doi:10.1007/s10552-008-9275-x CrossRefPubMed

40.

Jin H, Pinheiro PS, Xu J, Amei A (2016) Cancer incidence among Asian American populations in the United States, 2009-2011. Int J Cancer 138:2136–2145. doi:10.1002/ijc.29958 CrossRefPubMed

41.

Surh Y-J, Chun K-S (2007) Cancer chemopreventive effects of curcumin. Adv Exp Med Biol 595:149–172. doi:10.1007/978-0-387-46401-5_5 CrossRefPubMed

42.

Tayyem RF, Heath DD, Al-Delaimy WK, Rock CL (2006) Curcumin content of turmeric and curry powders. Nutr Cancer 55:126–131. doi:10.1207/s15327914nc5502_2 CrossRefPubMed

43.

Hajra A, Li Y, Siu S et al (2013) Risk of coronary disease in the South Asian American population. J Am Coll Cardiol 62:644–645. doi:10.1016/j.jacc.2013.05.048 CrossRefPubMed

44.

Kandula NR, Wen M, Jacobs EA, Lauderdale DS (2006) Low rates of colorectal, cervical, and breast cancer screening in Asian Americans compared with non-Hispanic whites: cultural influences or access to care? Cancer 107:184–192. doi:10.1002/cncr.21968 CrossRefPubMed

45.

Laiyemo AO, Doubeni C, Pinsky PF et al (2010) Race and colorectal cancer disparities: health-care utilization vs different cancer susceptibilities. J Natl Cancer Inst 102:538–546. doi:10.1093/jnci/djq068 CrossRefPubMedPubMedCentral

Title: Risk of cancer in Asian Americans: a Kaiser Permanente cohort study
Authors: H. Nicole Tran
Yan Li
Natalia Udaltsova
Mary Anne Armstrong
Gary D. Friedman
Arthur L. Klatsky
Publication date: 01-10-2016
Publisher: Springer International Publishing
Published in: Cancer Causes & Control / Issue 10/2016
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI: https://doi.org/10.1007/s10552-016-0798-2

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