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Cancer Causes & Control
Published in: Cancer Causes & Control 1/2014

01-01-2014 | Original paper

Lifestyle factors and health-related quality of life in colorectal cancer survivors

Authors: Sabrina Schlesinger, Jessica Walter, Jochen Hampe, Witigo von Schönfels, Sebastian Hinz, Thomas Küchler, Gunnar Jacobs, Clemens Schafmayer, Ute Nöthlings

Published in: Cancer Causes & Control | Issue 1/2014

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Abstract

Purpose

This study investigates the association between a postdiagnosis lifestyle score and health-related quality of life (HrQol) in long-term colorectal cancer (CRC) survivors.

Methods

A cross-sectional study of 1,389 long-term CRC survivors in Northern Germany was analyzed. On average 7.2 years after CRC diagnosis, HrQol was assessed with the EORTC QLQ-C30, and lifestyle factors, including weight, height, diet, physical activity, and smoking were obtained using self-administered questionnaires. A lifestyle score (BMI <30 kg/m², healthy diet, recreationally active, and not smoking) was applied. Participants were categorized in adhering to at most one, two, three, or all recommended lifestyle factors, categorizing unfavorable behaviors with 0 and favorable with 1 point. Multivariable logistic regression models were used to investigate the association between the lifestyle score and HrQol as a binary variable.

Results

Approximately 10 % had at most one, 30 % two, 38 % three, and 23 % all favorable factors. Compared to participants with one or zero factors, the odds ratio (OR) for a low global HrQol (gHrQol) decreased with stronger adherence to the score. The OR (95% CI) for a low gHrQol was 0.50 (0.33–0.76) for participants with all favorable lifestyle factors compared to participants with one or zero. Clinical and socio-demographic factors had little impact on these associations, with exception of living arrangement which showed a statistically significant interaction. Associations were stronger for functioning domains, representing mobility rather than mental health.

Conclusions

Favorable lifestyle behaviors might be associated with HrQol in CRC long-term survivors. More research in prospective studies is needed.
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Metadata
Title
Lifestyle factors and health-related quality of life in colorectal cancer survivors
Authors
Sabrina Schlesinger
Jessica Walter
Jochen Hampe
Witigo von Schönfels
Sebastian Hinz
Thomas Küchler
Gunnar Jacobs
Clemens Schafmayer
Ute Nöthlings
Publication date
01-01-2014
Publisher
Springer Netherlands
Published in
Cancer Causes & Control / Issue 1/2014
Print ISSN: 0957-5243
Electronic ISSN: 1573-7225
DOI
https://doi.org/10.1007/s10552-013-0313-y

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