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Brain Topography
Published in: Brain Topography 6/2019

01-11-2019 | Smelling Disorder | Review

Magnetic Resonance Imaging of Human Olfactory Dysfunction

Authors: Pengfei Han, Yunpeng Zang, Joshi Akshita, Thomas Hummel

Published in: Brain Topography | Issue 6/2019

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Abstract

Olfactory dysfunctions affect a larger portion of population (up to 15% with partial olfactory loss, and 5% with complete olfactory loss) as compared to other sensory dysfunctions (e.g. auditory or visual) and have a negative impact on the life quality. The impairment of olfactory functions may happen at each stage of the olfactory system, from epithelium to cortex. Non-invasive neuroimaging techniques such as the magnetic resonance imaging (MRI) have advanced the understanding of the advent and progress of olfactory dysfunctions in humans. The current review summarizes recent MRI studies on human olfactory dysfunction to present an updated and comprehensive picture of the structural and functional alterations in the central olfactory system as a consequence of olfactory loss and regain. Furthermore, the review also highlights recent progress on optimizing the olfactory functional MRI as well as new approaches for data processing that are promising for future clinical practice.
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Metadata
Title
Magnetic Resonance Imaging of Human Olfactory Dysfunction
Authors
Pengfei Han
Yunpeng Zang
Joshi Akshita
Thomas Hummel
Publication date
01-11-2019
Publisher
Springer US
Published in
Brain Topography / Issue 6/2019
Print ISSN: 0896-0267
Electronic ISSN: 1573-6792
DOI
https://doi.org/10.1007/s10548-019-00729-5

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