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Published in: Journal of Medical Ultrasonics 1/2021

01-01-2021 | Original Article–Obstetrics & Gynecology

Measurement of fetal automated fractional shortening using two-dimensional tracking in multiple centers

Authors: Sumito Nagasaki, Masahiko Nakata, Mayumi Takano, Junya Sakuma, Ryuhei Nagai, Susumu Miyashita, Yuichiro Takahashi, Shigenori Iwagaki, Yuka Yamamoto, Mineto Morita

Published in: Journal of Medical Ultrasonics | Issue 1/2021

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Abstract

Purpose

To establish a normal reference range for automated fractional shortening (Auto FS) in normal singleton fetuses measured at multiple centers.

Methods

This study was conducted from May 2017 to March 2019. It was undertaken on normal singleton fetuses. First, a four-chamber view of the fetal heart was recorded in the B-mode. Then, the region of interest was set on the edge of the ventricular septum and on the edge of the ventricular muscle at a point one-third away from the atrioventricular valve and toward the cardiac apex. Tracking was automatically performed. Values measured in the right ventricle were defined as R-Auto FS, and in the left ventricle as L-Auto FS. Furthermore, combined-Auto FS was defined as the measurement across both ventricles.

Results

A total of 442 normal fetuses were assessed. R-Auto FS decreased significantly with gestational age, and L-Auto FS showed a similar tendency (Spearman’s correlation analysis: rs =  − 0.415 and rs =  − 0.252, respectively). Combined-Auto FS showed a similar decline as the gestational age increased (rs =  − 0.451).

Conclusion

In this study, we succeeded in defining a reference Auto FS value not only at one institution but also multiple centers. This study suggests that Auto FS can be used clinically and effectively.
Literature
1.
go back to reference Nakata M, Sakuma J, Takano M, Nagasaki S. Assessment of fetal cardiac function with echocardiography. J Obstet Gynaecol Res. 2020;46:31–8.CrossRef Nakata M, Sakuma J, Takano M, Nagasaki S. Assessment of fetal cardiac function with echocardiography. J Obstet Gynaecol Res. 2020;46:31–8.CrossRef
2.
go back to reference DeVore GR, Klas B, Satou G, Sklansky M. Twenty-four segment transverse ventricular fractional shortening: a new technique to evaluate fetal cardiac function. J Ultrasound Med. 2018;37:1129–41.CrossRef DeVore GR, Klas B, Satou G, Sklansky M. Twenty-four segment transverse ventricular fractional shortening: a new technique to evaluate fetal cardiac function. J Ultrasound Med. 2018;37:1129–41.CrossRef
3.
go back to reference Luewan S, Yanase Y, Tongprasert F, Srisupundit K, Tongsong T. Fetal cardiac dimensions at 14–40 weeks’ gestation obtained using cardio-STIC-M. Ultrasound Obstet Gynecol. 2011;37:416–22.CrossRef Luewan S, Yanase Y, Tongprasert F, Srisupundit K, Tongsong T. Fetal cardiac dimensions at 14–40 weeks’ gestation obtained using cardio-STIC-M. Ultrasound Obstet Gynecol. 2011;37:416–22.CrossRef
4.
go back to reference Nagasaki S, Nakata M, Takano M, Usui K, Sakuma J, Hayata E, et al. Feasibility of automated fetal fractional shortening measurement with two-dimensional tracking and construction of a reference range for normal fetuses. J Med Ultrason. 2001;2019(46):467–72. Nagasaki S, Nakata M, Takano M, Usui K, Sakuma J, Hayata E, et al. Feasibility of automated fetal fractional shortening measurement with two-dimensional tracking and construction of a reference range for normal fetuses. J Med Ultrason. 2001;2019(46):467–72.
5.
go back to reference Royston P, Wright EM. How to construct ‘normal ranges’ for fetal variables. Ultrasound Obst Gyn. 1998;11:30–8.CrossRef Royston P, Wright EM. How to construct ‘normal ranges’ for fetal variables. Ultrasound Obst Gyn. 1998;11:30–8.CrossRef
6.
go back to reference DeVore GR. Computing the Z Score and centiles for cross-sectional analysis: a practical approach. J Ultrasound Med. 2017;36:459–73.CrossRef DeVore GR. Computing the Z Score and centiles for cross-sectional analysis: a practical approach. J Ultrasound Med. 2017;36:459–73.CrossRef
7.
go back to reference Takano M, Nakata M, Nagasaki S, Ueyama R, Morita M. Assessment of diastolic function of normal fetal heart using dual-gate Doppler. Ultrasound Obstet Gynecol. 2018;52:238–42.CrossRef Takano M, Nakata M, Nagasaki S, Ueyama R, Morita M. Assessment of diastolic function of normal fetal heart using dual-gate Doppler. Ultrasound Obstet Gynecol. 2018;52:238–42.CrossRef
8.
go back to reference Huhta JC. Guidelines for the evaluation of heart failure in the fetus with or without hydrops. Pediatr Cardiol. 2004;25:274–86.CrossRef Huhta JC. Guidelines for the evaluation of heart failure in the fetus with or without hydrops. Pediatr Cardiol. 2004;25:274–86.CrossRef
9.
go back to reference Vore GR, Siassi B, Platt LD. Fetal echocardiography. IV. M-mode assessment of ventricular size and contractility during the second and third trimesters of pregnancy in the normal fetus. Am J Obstet Gynecol. 1984;150:981–8.CrossRef Vore GR, Siassi B, Platt LD. Fetal echocardiography. IV. M-mode assessment of ventricular size and contractility during the second and third trimesters of pregnancy in the normal fetus. Am J Obstet Gynecol. 1984;150:981–8.CrossRef
10.
go back to reference John Sutton MG, Gewitz MH, Shah B, Cohen A, Reichek N, Gabbe S, et al. Quantitative assessment of growth and function of the cardiac chambers in the normal human fetus: a prospective longitudinal echocardiographic study. Circulation. 1984;69:645–54.CrossRef John Sutton MG, Gewitz MH, Shah B, Cohen A, Reichek N, Gabbe S, et al. Quantitative assessment of growth and function of the cardiac chambers in the normal human fetus: a prospective longitudinal echocardiographic study. Circulation. 1984;69:645–54.CrossRef
11.
go back to reference Johnson P, Maxwell DJ, Tynan MJ, Allan LD. Intracardiac pressures in the human fetus. Heart. 2000;84:59–63.CrossRef Johnson P, Maxwell DJ, Tynan MJ, Allan LD. Intracardiac pressures in the human fetus. Heart. 2000;84:59–63.CrossRef
12.
go back to reference Rasanen J, Wood DC, Weiner S, Ludomirski A, Huhta JC. Role of the pulmonary circulation in the distribution of human fetal cardiac output during the second half of pregnancy. Circulation. 1996;94:1068–73.CrossRef Rasanen J, Wood DC, Weiner S, Ludomirski A, Huhta JC. Role of the pulmonary circulation in the distribution of human fetal cardiac output during the second half of pregnancy. Circulation. 1996;94:1068–73.CrossRef
Metadata
Title
Measurement of fetal automated fractional shortening using two-dimensional tracking in multiple centers
Authors
Sumito Nagasaki
Masahiko Nakata
Mayumi Takano
Junya Sakuma
Ryuhei Nagai
Susumu Miyashita
Yuichiro Takahashi
Shigenori Iwagaki
Yuka Yamamoto
Mineto Morita
Publication date
01-01-2021
Publisher
Springer Singapore
Published in
Journal of Medical Ultrasonics / Issue 1/2021
Print ISSN: 1346-4523
Electronic ISSN: 1613-2254
DOI
https://doi.org/10.1007/s10396-020-01069-9

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