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Japanese Journal of Ophthalmology
Published in: Japanese Journal of Ophthalmology 1/2019

01-01-2019 | Clinical Investigation

Current status of late and recurrent intraocular lens dislocation: analysis of real-world data in Japan

Authors: Sumihiro Kawano, Masato Takeuchi, Shiro Tanaka, Takehiro Yamashita, Taiji Sakamoto, Koji Kawakami

Published in: Japanese Journal of Ophthalmology | Issue 1/2019

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Abstract

Purpose

To describe relevant patient demographic characteristics and investigate the influence of known risk factors for late intraocular lens (IOL) dislocation. To explore the associations between these risk factors and the incidence of recurrent IOL dislocation.

Study design

Retrospective cohort study.

Methods

This study was performed using Nationwide Diagnostic Procedure Combination data in Japan from April 1, 2008 through July 31, 2016. Descriptive statistics for late and recurrent IOL dislocation, incidence rates, and risk factors for recurrent IOL dislocation were analyzed using a Cox proportional hazard model.

Results

We identified 678 patients with late IOL dislocation. Most were men (72%, 488/678), and the men were younger than their women counterparts (mean age 65.2 years vs. 74.5 years). The incidence rate of recurrent IOL dislocation was 5.1 per 100 person-years. All 20 cases of recurrent IOL dislocation were observed within the year following surgery. There were no significant associations between potential risk factors and recurrent IOL dislocation (adjusted hazard ratio [HR] 1.53, 95% confidence interval [CI] 0.55–4.26 for diabetes mellitus; adjusted HR 0.77, 95%CI 0.09–6.40 for atopic dermatitis); no recurrences occurred in patients with pseudoexfoliation syndrome, retinitis pigmentosa, or connective tissue disease.

Conclusions

Late IOL dislocation occurs more frequently in men. We found that recurrent IOL dislocation was rare during long-term follow-up and there were no significant associations between the potential risk factors and recurrent IOL dislocation. Further studies are needed to clarify the sex-related differences involved in IOL dislocation.
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Metadata
Title
Current status of late and recurrent intraocular lens dislocation: analysis of real-world data in Japan
Authors
Sumihiro Kawano
Masato Takeuchi
Shiro Tanaka
Takehiro Yamashita
Taiji Sakamoto
Koji Kawakami
Publication date
01-01-2019
Publisher
Springer Japan
Published in
Japanese Journal of Ophthalmology / Issue 1/2019
Print ISSN: 0021-5155
Electronic ISSN: 1613-2246
DOI
https://doi.org/10.1007/s10384-018-0637-y

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